Zobrazeno 1 - 10
of 171
pro vyhledávání: '"Daniel, Todt"'
Autor:
Michael Hermann Wißing, Toni Luise Meister, Maximilian Klaus Nocke, André Gömer, Mejrema Masovic, Leonard Knegendorf, Yannick Brüggemann, Verian Bader, Anindya Siddharta, Claus-Thomas Bock, Alexander Ploss, Scott P. Kenney, Konstanze F. Winklhofer, Patrick Behrendt, Heiner Wedemeyer, Eike Steinmann, Daniel Todt
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract Hepatitis E virus (HEV) is a long-neglected RNA virus and the major causative agent of acute viral hepatitis in humans. Recent data suggest that HEV has a very heterogeneous hypervariable region (HVR), which can tolerate major genomic rearra
Externí odkaz:
https://doaj.org/article/36a2243de9ad4d3885e1b54753f3ea25
Publikováno v:
Emerging Infectious Diseases, Vol 30, Iss 5, Pp 934-940 (2024)
To determine the kinetics of hepatitis E virus (HEV) in asymptomatic persons and to evaluate viral load doubling time and half-life, we retrospectively tested samples retained from 32 HEV RNA-positive asymptomatic blood donors in Germany. Close-meshe
Externí odkaz:
https://doaj.org/article/544334126e5741c8b635fa82e479d053
Autor:
Toni Luise Meister, Nicola Frericks, Robin D V Kleinert, Estefanía Rodríguez, Joerg Steinmann, Daniel Todt, Richard J P Brown, Eike Steinmann
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 18, Iss 6, p e0012264 (2024)
Despite continued outbreaks of yellow fever virus (YFV) in endemic regions, data on its environmental stability or guidelines for its effective inactivation is limited. Here, we evaluated the susceptibility of the YFV 17D vaccine strain to inactivati
Externí odkaz:
https://doaj.org/article/de10d59daa5749329f78054bec667369
Autor:
André Gömer, Katja Dinkelborg, Mara Klöhn, Michelle Jagst, Michael Hermann Wißing, Nicola Frericks, Pia Nörenberg, Patrick Behrendt, Markus Cornberg, Heiner Wedemeyer, Eike Steinmann, Benjamin Maasoumy, Daniel Todt
Publikováno v:
JHEP Reports, Vol 6, Iss 3, Pp 100989- (2024)
Background & Aims: In the absence of a hepatitis E virus (HEV)-specific antiviral treatment, sofosbuvir has recently been shown to have antiviral activity against HEV in vivo. However, a variant, A1343V, that is strongly associated with viral relapse
Externí odkaz:
https://doaj.org/article/ca23583ef8d0487da1ab21c7ddd9e36c
Autor:
Ola Bagato, Anne Balkema-Buschmann, Daniel Todt, Saskia Weber, André Gömer, Bingqian Qu, Csaba Miskey, Zoltan Ivics, Thomas C. Mettenleiter, Stefan Finke, Richard J. P. Brown, Angele Breithaupt, Dmitry S. Ushakov
Publikováno v:
Microbiology Spectrum, Vol 12, Iss 1 (2024)
ABSTRACT Lung immune response to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is critical for the ability to deal with infection. Using light sheet fluorescence microscopy of hamster lung slices in combination with virological, immuno
Externí odkaz:
https://doaj.org/article/752b1d6443b247df8da3809cbeaac0e7
Autor:
Toni L. Meister, Ronny Tao, Yannick Brüggemann, Daniel Todt, Joerg Steinmann, Joerg Timm, Ingo Drexler, Eike Steinmann
Publikováno v:
Emerging Infectious Diseases, Vol 29, Iss 1, Pp 189-192 (2023)
Increasing nonzoonotic human monkeypox virus (MPXV) infections urge reevaluation of inactivation strategies. We demonstrate efficient inactivation of MPXV by 2 World Health Organization‒recommended alcohol-based hand rub solutions. When compared wi
Externí odkaz:
https://doaj.org/article/4c39aaf2a3d64dd2adf54adce5bbc592
Autor:
Yudi Zhang, Volker Kinast, Julie Sheldon, Nicola Frericks, Daniel Todt, Matthias Zimmer, Neva Caliskan, Richard J. P. Brown, Eike Steinmann, Thomas Pietschmann
Publikováno v:
Microbiology Spectrum, Vol 11, Iss 4 (2023)
ABSTRACT Mice are refractory to infection with human-tropic hepatitis C virus (HCV), although distantly related rodent hepaciviruses (RHV) circulate in wild rodents. To investigate whether liver intrinsic host factors can exhibit broad restriction ag
Externí odkaz:
https://doaj.org/article/49181b3ec16a43678eaa9634d45b4129
Autor:
André Gömer, Christina Puff, Birthe Reinecke, Stephanie Bracht, Maria Conze, Wolfgang Baumgärtner, Jörg Steinmann, Karsten Feige, Jessika M. V. Cavalleri, Eike Steinmann, Daniel Todt
Publikováno v:
One Health Outlook, Vol 4, Iss 1, Pp 1-11 (2022)
Abstract Background The Equine Hepacivirus (EqHV) is an equine-specific and liver-tropic virus belonging to the diverse genus of Hepaciviruses. It was recently found in a large donkey (Equus asinus) cohort with a similar seroprevalence (30%), but low
Externí odkaz:
https://doaj.org/article/cbd4630e7ceb46339e8329f4650e3b96
Autor:
Natalie Heinen, Corinna Sophie Marheinecke, Clara Bessen, Arturo Blazquez-Navarro, Toralf Roch, Ulrik Stervbo, Moritz Anft, Carlos Plaza-Sirvent, Sandra Busse, Mara Klöhn, Jil Schrader, Elena Vidal Blanco, Doris Urlaub, Carsten Watzl, Markus Hoffmann, Stefan Pöhlmann, Matthias Tenbusch, Eike Steinmann, Daniel Todt, Carsten Hagenbeck, Gert Zimmer, Wolfgang Ekkehard Schmidt, Daniel Robert Quast, Nina Babel, Ingo Schmitz, Stephanie Pfänder
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
With the emergence of novel Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) Variants of Concern (VOCs), vaccination studies that elucidate the efficiency and effectiveness of a vaccination campaign are critical to assess the durability a
Externí odkaz:
https://doaj.org/article/77dc03f4f7d54c428069378f6feeec11
Autor:
André Gömer, Julien Delarocque, Christina Puff, Maximilian K. Nocke, Birthe Reinecke, Wolfgang Baumgärtner, Jessika M. V. Cavalleri, Karsten Feige, Eike Steinmann, Daniel Todt
Publikováno v:
Microbiology Spectrum, Vol 10, Iss 5 (2022)
ABSTRACT More than 70 million people worldwide are still infected with the hepatitis C virus 30 years after its discovery, underscoring the need for a vaccine. To develop an effective prophylactic vaccine, detailed knowledge of the correlates of prot
Externí odkaz:
https://doaj.org/article/4e872a412289469db2f3642ff7582b9a