Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Daniel, Schimel"'
Autor:
Temeri Wilder-Kofie, Daniel L. Barber, Laura E. Via, M Sutphin, Juraj Kabat, Shunsuke Sakai, Keith D. Kauffman, Clifton E. Barry, Danielle M. Weiner, Olena Kamenyeva, Ian N. Moore, Daniel Schimel, Michelle A. Sallin, Rashida Moore
Publikováno v:
Mucosal immunology
Protection against Mycobacterium tuberculosis (Mtb) infection requires CD4 T cells to migrate into the lung and interact with infected macrophages. In mice, less-differentiated CXCR3+ CD4 T cells migrate into the lung and suppress growth of Mtb, wher
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6a7754b0bb230ead13629e2cc444628
https://doi.org/10.1038/mi.2017.60
https://doi.org/10.1038/mi.2017.60
Autor:
Véronique Dartois, Lori E. Dodd, Katherine K. Robbins, Danielle M. Weiner, Daniel Schimel, Clifton E. Barry, Kathleen England, Ray Y. Chen, Matthew D. Zimmerman, Dima A. Hammoud, JoAnne L. Flynn, Laura E. Via, Peter Herscovitch, Emmanuel Dayao, Mike Richardson, Ying Cai
Publikováno v:
Antimicrobial Agents and Chemotherapy. 59:4181-4189
Shortening the lengthy treatment duration for tuberculosis patients is a major goal of current drug development efforts. The common marmoset develops human-like disease pathology and offers an attractive model to better understand the basis for relap
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4208851a5adfe979358cced88f0f8d7
https://doi.org/10.1128/aac.00115-15
https://doi.org/10.1128/aac.00115-15
Autor:
John D. Martin, Meenal Datta, Lei Xu, Clifton E. Barry, Rakesh K. Jain, Walid S. Kamoun, Wei Chen, Kathleen England, Laura E. Via, Daniel Schimel, Chong Liu, Danielle M. Weiner, Giorgio Seano, Xing Gao
Publikováno v:
Proceedings of the National Academy of Sciences. 112:1827-1832
Tuberculosis (TB) causes almost 2 million deaths annually, and an increasing number of patients are resistant to existing therapies. Patients who have TB require lengthy chemotherapy, possibly because of poor penetration of antibiotics into granuloma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::274a99f9cbf394ab1b01403af653efc4
https://doi.org/10.1073/pnas.1424563112
https://doi.org/10.1073/pnas.1424563112
Autor:
Kathleen England, Clifton E. Barry, Emmanuel Dayao, Daniel Schimel, Helena I. Boshoff, Laura E. Via, Danielle M. Weiner, Kriti Arora
Publikováno v:
Antimicrobial Agents and Chemotherapy. 56:3384-3387
The carbapenems imipenem and meropenem in combination with clavulanic acid reduced the bacterial burden in Mycobacterium tuberculosis -infected macrophages by 2 logs over 6 days. Despite poor stability in solution and a short half-life in rodents, tr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91b17e2c68baa65a9bbadddeeedf2009
https://doi.org/10.1128/aac.05690-11
https://doi.org/10.1128/aac.05690-11
Autor:
Richard Kvetnansky, Marcelino Bernardo, Peter L. Choyke, James F. Powers, Edwin W. Lai, Maria J. Merino, Daniel Schimel, Melanie Suzanne Kotys, Karel Pacak, J. Ruzicka, David Thomasson, Lucia Martiniova
Publikováno v:
Journal of Magnetic Resonance Imaging. 29:685-691
Purpose To compare contrast-enhanced micro-computed tomography (microCT) and nonenhanced respiratory-triggered magnetic resonance imaging (MRI) in an animal model of metastatic pheochromocytoma. Animal models are becoming important in the study of ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5acd0d3279cfb9921f1d1863c0f4b4e
https://doi.org/10.1002/jmri.21654
https://doi.org/10.1002/jmri.21654
Autor:
Trinity J. Bivalacqua, Alan N. Schechter, Mark T. Gladwin, Lewis L. Hsu, Audrey E. Cochard, Xunde Wang, Daniel Schimel, Elizabeth A. Manci, Hunter C. Champion, Sally Campbell-Lee, Bhalchandra A. Diwan, Constance Tom Noguchi
Publikováno v:
Blood. 109:3088-3098
Pulmonary hypertension is a highly prevalent complication of sickle cell disease and is a strong risk factor for early mortality. However, the pathophysiological mechanisms by which sickle hemoglobin leads to pulmonary vasculopathy remain unclear. Tr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ac5976025f1c82420455308f9979632
https://doi.org/10.1182/blood-2006-08-039438
https://doi.org/10.1182/blood-2006-08-039438
Autor:
Edwin W. Lai, Peter Guion, Karel Pacak, Shoichiro Ohta, Daniel Schimel, Elaine M. Jagoda, Brenda Klaunberg, Lucia Martiniova
Publikováno v:
Annals of the New York Academy of Sciences. 1073:392-404
This review focuses on anatomical (computed tomography, magnetic resonance imaging) and functional (positron emission tomography) imaging methods for tumor localization and identification of experimentally induced tumors in animal models, especially
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3edb3cb1c245b5c4aca5f01c64daa9d
https://doi.org/10.1196/annals.1353.043
https://doi.org/10.1196/annals.1353.043
Autor:
Brenda A. Klaunberg, James F. Powers, Daniel Schimel, Edwin W. Lai, Karel Pacak, Shoichiro Ohta, Douglas A. Bakan, John C. Morris, Susannah Cleary, Arthur S. Tischler, Mones Abu-Asab
Publikováno v:
International Journal of Cancer. 119:2236-2241
Successful outcomes for patients with cancer often depend on the early detection of tumor and the prompt initiation of active therapy. Despite major advances in the treatment of many cancers, early-stage lesions often go undetected due to the subopti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::31cf1519f7b49f31f77d393da90a8a7d
https://doi.org/10.1002/ijc.22127
https://doi.org/10.1002/ijc.22127
Autor:
Hisataka Kobayashi, Takahiro Watanabe, Mark A. Bryant, Katherine A. Staskus, Philipp Kaldis, Andrew Blauvelt, Daniel Schimel, Elisabeth A. Hanan, Debra L. Borris, Makoto Sugaya, Mihaela Skobe, Matthew F. Starost, Aparche Yang, Nicole Roberts, April M. Atkins
Publikováno v:
Blood. 105:2356-2363
Kaposi sarcoma–associated herpesvirus (KSHV) infects endothelial cells within KS tumors, and these cells express the KSHV latent-cycle gene k-cyclin (kCYC) as well as vascular endothelial growth factor receptor 3 (VEGFR-3), a marker for lymphatic e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00a3aae9578051528beef7511f4f7836
https://doi.org/10.1182/blood-2004-08-3364
https://doi.org/10.1182/blood-2004-08-3364
Autor:
Saher Lahouar, Sebastien Gagneux, Michael Tartakovsky, Praveen Paripati, Emmanuel Dayao, JoAnne L. Flynn, Laura E. Via, Ying Cai, Jaime Tomko, Alex Rosenthal, Philana Ling Lin, Seok Yong Eum, Sarah L. Tankersley, Damien Portevin, Danielle M. Weiner, Clifton E. Barry, Robin J. Kastenmayer, M. Teresa Coleman, Douglas B. Young, Daniel Schimel, Marlene Orandle
Publikováno v:
ResearcherID
Infection and immunity
Infection and immunity
Existing small-animal models of tuberculosis (TB) rarely develop cavitary disease, limiting their value for assessing the biology and dynamics of this highly important feature of human disease. To develop a smaller primate model with pathology simila
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf861aa0950316c4962871dede661ad6
https://europepmc.org/articles/PMC3719573/
https://europepmc.org/articles/PMC3719573/
