Zobrazeno 1 - 10
of 471
pro vyhledávání: '"Daniel, Scherman"'
Autor:
Jeremy L. Pinyon, Georg vonJonquieres, Edward N. Crawford, Amr Al Abed, John M. Power, Matthias Klugmann, Cherylea J. Browne, David M. Housley, Andrew K. Wise, James B. Fallon, Robert K. Shepherd, John Y. Lin, Catherine McMahon, David McAlpine, Catherine S. Birman, Waikong Lai, Ya Lang Enke, Paul M. Carter, James F. Patrick, Robert D. Gay, Corinne Marie, Daniel Scherman, Nigel H. Lovell, Gary D. Housley
Publikováno v:
Advanced Science, Vol 11, Iss 30, Pp n/a-n/a (2024)
Abstract Viral vectors and lipofection‐based gene therapies have dispersion‐dependent transduction/transfection profiles that thwart precise targeting. The study describes the development of focused close‐field gene electrotransfer (GET) techno
Externí odkaz:
https://doaj.org/article/1f120ece41dd42df991a8e5de27489c2
Autor:
Hai Doan Do, Corinne Marie, Stéphanie Bessoles, Hélène Dhotel, Johanne Seguin, Benoit Larrat, Bich-Thuy Doan, Daniel Scherman, Virginie Escriou, Salima Hacein-Bey-Abina, Nathalie Mignet
Publikováno v:
Exploration of Targeted Anti-tumor Therapy, Vol 3, Iss 3, Pp 398-413 (2022)
Aim: Gene-based immunotherapy against cancer is limited by low gene transfer efficiency. In the literature, interleukin-12 (IL-12) encoding plasmid associated with sonoporation has been shown to enhance antitumoral activity. Moreover, non-viral carr
Externí odkaz:
https://doaj.org/article/755a37e131c8442190d977af4f4c1990
Autor:
Daniel Scherman
This unique advanced textbook provides a clear and comprehensive description of the field of gene delivery, gene therapy and genetic pharmacology, with descriptions of the main gene transfer vectors and a set of selected therapeutic applications, alo
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 21, Iss , Pp 28-36 (2020)
Non-viral gene delivery into the liver generally mediates a transient transgene expression. A comparative analysis was performed using two gene vectors, pFAR4 and pKAR4, which differ by the absence or presence of an antibiotic resistance marker, resp
Externí odkaz:
https://doaj.org/article/88d87a4e366b4458a33d07524b32cc22
Autor:
Maria Hernandez, Sergio Recalde, Laura Garcia-Garcia, Jaione Bezunartea, Csaba Miskey, Sandra Johnen, Sabine Diarra, Attila Sebe, Juan Roberto Rodriguez-Madoz, Severine Pouillot, Corinne Marie, Zsuzsanna Izsvák, Daniel Scherman, Martina Kropp, Felipe Prosper, Gabriele Thumann, Zoltán Ivics, Alfredo Garcia-Layana, Patricia Fernandez-Robredo
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 15, Iss , Pp 403-417 (2019)
Age-related macular degeneration (AMD) is a progressive retinal disorder characterized by imbalanced pro- and antiangiogenic signals. The aim of this study was to evaluate the effect of ex vivo cell-based gene therapy with stable expression of human
Externí odkaz:
https://doaj.org/article/5d42b7be628d4feab08c70665676e92a
Autor:
Martina Kropp, Nina Harmening, Thais Bascuas, Sandra Johnen, Eline De Clerck, Verónica Fernández, Mattia Ronchetti, Ruggero Cadossi, Cristina Zanini, Daniel Scherman, Zoltán Ivics, Corinne Marie, Zsuzsanna Izsvák, Gabriele Thumann
Publikováno v:
Biomedicines, Vol 10, Iss 11, p 2777 (2022)
The introduction of new therapeutics requires validation of Good Manufacturing Practice (GMP)-grade manufacturing including suitable quality controls. This is challenging for Advanced Therapy Medicinal Products (ATMP) with personalized batches. We ha
Externí odkaz:
https://doaj.org/article/c655be284c8d4e29b949da37ad4ad48e
Autor:
Jianhua Liu, Lenka Kotrchová, Thomas Lécuyer, Yohann Corvis, Johanne Seguin, Nathalie Mignet, Tomáš Etrych, Daniel Scherman, Eva Randárová, Cyrille Richard
Publikováno v:
Frontiers in Chemistry, Vol 8 (2020)
Persistent luminescence nanoparticles (PLNPs) are innovative nanomaterials highly useful for bioimaging applications. Indeed, due to their particular optical properties, i.e., the ability to store the excitation energy before slowly releasing it for
Externí odkaz:
https://doaj.org/article/0c0d75632f584185b83320e9ca8c384c
Autor:
Marie Pastor, Sandra Johnen, Nina Harmening, Mickäel Quiviger, Julie Pailloux, Martina Kropp, Peter Walter, Zoltán Ivics, Zsuzsanna Izsvák, Gabriele Thumann, Daniel Scherman, Corinne Marie
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 11, Iss C, Pp 57-67 (2018)
The anti-angiogenic and neurogenic pigment epithelium-derived factor (PEDF) demonstrated a potency to control choroidal neovascularization in age-related macular degeneration (AMD) patients. The goal of the present study was the development of an eff
Externí odkaz:
https://doaj.org/article/c0102cc49ae944f381497e5360d1481b
Autor:
Laura Garcia-Garcia, Sergio Recalde, Maria Hernandez, Jaione Bezunartea, Juan Roberto Rodriguez-Madoz, Sandra Johnen, Sabine Diarra, Corinne Marie, Zsuzsanna Izsvák, Zoltán Ivics, Daniel Scherman, Martina Kropp, Gabriele Thumann, Felipe Prosper, Patricia Fernandez-Robredo, Alfredo Garcia-Layana
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 9, Iss C, Pp 1-11 (2017)
Pigment epithelium derived factor (PEDF) is a potent antiangiogenic, neurotrophic, and neuroprotective molecule that is the endogenous inhibitor of vascular endothelial growth factor (VEGF) in the retina. An ex vivo gene therapy approach based on tra
Externí odkaz:
https://doaj.org/article/51aa99e26a564226b809d73b46562a94
Autor:
Gabriele Thumann, Nina Harmening, Cécile Prat-Souteyrand, Corinne Marie, Marie Pastor, Attila Sebe, Csaba Miskey, Laurence D. Hurst, Sabine Diarra, Martina Kropp, Peter Walter, Daniel Scherman, Zoltán Ivics, Zsuzsanna Izsvák, Sandra Johnen
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 6, Iss , Pp 302-314 (2017)
Neovascular age-related macular degeneration (nvAMD) is characterized by choroidal blood vessels growing into the subretinal space, leading to retinal pigment epithelial (RPE) cell degeneration and vision loss. Vessel growth results from an imbalance
Externí odkaz:
https://doaj.org/article/3ef7533fe13543258264496282a1f989