Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Daniel, Normolle"'
Autor:
John J. Skoko, Juxiang Cao, David Gaboriau, Myriam Attar, Alparslan Asan, Lisa Hong, Candice E. Paulsen, Hongqiang Ma, Yang Liu, Hanzhi Wu, Trey Harkness, Cristina M. Furdui, Yefim Manevich, Ciaran G. Morrison, Erika T. Brown, Daniel Normolle, Maria Spies, Michael Ashley Spies, Kate Carroll, Carola A. Neumann
Publikováno v:
Redox Biology, Vol 56, Iss , Pp 102443- (2022)
RAD51 is a critical recombinase that functions in concert with auxiliary mediator proteins to direct the homologous recombination (HR) DNA repair pathway. We show that Cys319 RAD51 possesses nucleophilic characteristics and is important for irradiati
Externí odkaz:
https://doaj.org/article/2fc66d80d6fa4b56ae9f41a240a26b8a
Autor:
Lan G. Coffman, Taylor J. Orellana, Tianshi Liu, Leonard G. Frisbie, Daniel Normolle, Kent Griffith, Shitanshu Uppal, Karen McLean, Jessica Berger, Michelle Boisen, Madeleine Courtney-Brooks, Robert P. Edwards, Jamie Lesnock, Haider Mahdi, Alexander Olawaiye, Paniti Sukumvanich, Sarah E. Taylor, Ronald Buckanovich
Publikováno v:
JCI Insight, Vol 7, Iss 18 (2022)
BACKGROUND New therapeutic combinations to improve outcomes of patients with ovarian cancer are clearly needed. Preclinical studies with ribociclib (LEE-011), a CDK4/6 cell cycle checkpoint inhibitor, demonstrate a synergistic effect with platinum ch
Externí odkaz:
https://doaj.org/article/0e91eac13b934298960720568bddbce7
Autor:
Greg M Delgoffe, Kristin DePeaux, Angen Liu, Dan P Zandberg, Ashley V Menk, Maria Velez, Daniel Normolle
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss 5 (2021)
The majority of patients with recurrent/metastatic squamous cell carcinoma of the head and neck (HNSCC) (R/M) do not benefit from anti-PD-1 therapy. Hypoxia induced immunosuppression may be a barrier to immunotherapy. Therefore, we examined the metab
Externí odkaz:
https://doaj.org/article/d0916971c66149a6a4ea79c16d0bb5d0
Autor:
Daniel Normolle, Theodore S. Lawrence, Jonathan Maybaum, Leslie A. Parsels, Meredith A. Morgan, Lili Zhao
CCR Translation for This Article from Bayesian Hierarchical Changepoint Methods in Modeling the Tumor Growth Profiles in Xenograft Experiments
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a74c79c0ec2b81720f75e64092f12742
https://doi.org/10.1158/1078-0432.22444494.v1
https://doi.org/10.1158/1078-0432.22444494.v1
Autor:
Daniel Normolle, Theodore S. Lawrence, Jonathan Maybaum, Leslie A. Parsels, Meredith A. Morgan, Lili Zhao
Purpose: The standard approach of using tumor doubling time to assess growth delay may not accurately represent tumor response, especially if the growth rates are not constant. Therefore, we developed a method to compare the antitumor activities of d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17be93dc30c5401a790ee3fcb9f481ec
https://doi.org/10.1158/1078-0432.c.6520200.v1
https://doi.org/10.1158/1078-0432.c.6520200.v1
Autor:
Pawel Kalinski, David L. Bartlett, Todd A. Reinhart, The Minh Luong, Daniel Normolle, Amer H. Zureikat, Herbert J. Zeh, Beth Fallert Junecko, Erik Berk, Ravikumar Muthuswamy
PDF file - 191K, Processing of tumors and marginal tissues
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0465eba245ee43b14a1043e44452af62
https://doi.org/10.1158/0008-5472.22393811.v1
https://doi.org/10.1158/0008-5472.22393811.v1
Autor:
Pawel Kalinski, David L. Bartlett, Todd A. Reinhart, The Minh Luong, Daniel Normolle, Amer H. Zureikat, Herbert J. Zeh, Beth Fallert Junecko, Erik Berk, Ravikumar Muthuswamy
PDF file - 215K, Presence of Treg and Teff markers in tumors correlate with intra-tumoral expression of Teff- and Treg-attracting chemokines
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::879a01d0c9bc4498a1f7c92f88a05c3a
https://doi.org/10.1158/0008-5472.22393808
https://doi.org/10.1158/0008-5472.22393808
Autor:
Pawel Kalinski, David L. Bartlett, Todd A. Reinhart, The Minh Luong, Daniel Normolle, Amer H. Zureikat, Herbert J. Zeh, Beth Fallert Junecko, Erik Berk, Ravikumar Muthuswamy
Tumor infiltration with effector CD8+ T cells (Teff) predicts longer recurrence-free survival in many types of human cancer, illustrating the broad significance of Teff for effective immunosurveillance. Colorectal tumors with reduced accumulation of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::680f439e21176596400a3c2f0b84a1fd
https://doi.org/10.1158/0008-5472.c.6503282.v1
https://doi.org/10.1158/0008-5472.c.6503282.v1
Autor:
Pawel Kalinski, David L. Bartlett, Todd A. Reinhart, The Minh Luong, Daniel Normolle, Amer H. Zureikat, Herbert J. Zeh, Beth Fallert Junecko, Erik Berk, Ravikumar Muthuswamy
PDF file - 109K, CCL22 is predominantly expressed by HLA-DR+ APC, whereas CXCL10 and CCL5 are expressed by both HLA-DR positive and negative cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4fa4c8ccc1c6cf98fa1a78f4cc4ac53a
https://doi.org/10.1158/0008-5472.22391528.v1
https://doi.org/10.1158/0008-5472.22391528.v1
Autor:
Pawel Kalinski, David L. Bartlett, Todd A. Reinhart, The Minh Luong, Daniel Normolle, Amer H. Zureikat, Herbert J. Zeh, Beth Fallert Junecko, Erik Berk, Ravikumar Muthuswamy
PDF file - 17K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46808531800e56d2aed993de55d46231
https://doi.org/10.1158/0008-5472.22391519.v1
https://doi.org/10.1158/0008-5472.22391519.v1