Zobrazeno 1 - 10
of 119
pro vyhledávání: '"Daniel, Mucida"'
Downregulation of chemokine receptor 9 facilitates CD4+CD8αα+ intraepithelial lymphocyte development
Autor:
Keiko Ono, Tomohisa Sujino, Kentaro Miyamoto, Yosuke Harada, Satoshi Kojo, Yusuke Yoshimatsu, Shun Tanemoto, Yuzo Koda, Jiawen Zheng, Kazutoshi Sayama, Tsuyoshi Koide, Toshiaki Teratani, Yohei Mikami, Kaoru Takabayashi, Nobuhiro Nakamoto, Naoki Hosoe, Mariya London, Haruhiko Ogata, Daniel Mucida, Ichiro Taniuchi, Takanori Kanai
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-15 (2023)
Abstract Intestinal intraepithelial lymphocytes (IELs) reside in the gut epithelial layer, where they help in maintaining intestinal homeostasis. Peripheral CD4+ T cells can develop into CD4+CD8αα+ IELs upon arrival at the gut epithelium via the la
Externí odkaz:
https://doaj.org/article/f3798e0a3c1041ce9d72da327e0971b3
Autor:
Sandra Nakandakari-Higa, Roham Parsa, Bernardo S. Reis, Renan V. H. de Carvalho, Luka Mesin, Hans-Heinrich Hoffmann, Juliana Bortolatto, Hiromi Muramatsu, Paulo. J. C. Lin, Angelina M. Bilate, Charles M. Rice, Norbert Pardi, Daniel Mucida, Gabriel D. Victora, Maria Cecilia C. Canesso
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Efficient mouse models to study SARS-CoV-2 infection are critical for the development and assessment of vaccines and therapeutic approaches to mitigate the current pandemic and prevent reemergence of COVID-19. While the first generation of mouse mode
Externí odkaz:
https://doaj.org/article/03a40c2ab38f4b908a732a3ff73ed920
Publikováno v:
STAR Protocols, Vol 3, Iss 1, Pp 101157- (2022)
Summary: The myenteric plexus is located between the longitudinal and circular layers of muscularis externa in the gastrointestinal tract. It contains a large network of enteric neurons that form the enteric nervous system (ENS) and control intestina
Externí odkaz:
https://doaj.org/article/708d5e0f2018465fb6993e46d5d39967
Autor:
Dong-Yoon, Kim, Daniel, Mucida
Publikováno v:
Immunity. 55:2228-2230
Diverse intestinal components (e.g., gut-associated neurons, immune cells, gut microbes, and epithelium) are intimately intertwined with each other to maintain homeostasis in the gut. In a recent issue of Cell, Zhang et al. (2022) and Yang et al. (20
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04d67d0f80038617d18c4ea70b52841e
https://doi.org/10.1016/j.immuni.2022.11.006
https://doi.org/10.1016/j.immuni.2022.11.006
Autor:
Ainsley Lockhart, Aubrey Reed, Tiago Rezende de Castro, Calvin Herman, Maria Cecilia Campos Canesso, Daniel Mucida
Publikováno v:
bioRxiv
The intestinal immune system must tolerate food antigens to avoid allergy, a process requiring CD4+T cells. Combining antigenically defined diets with gnotobiotic models, we show that food and microbiota distinctly influence the profile and T cell re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81d965fa5cd2073c4fae3a7e6fc60d91
https://europepmc.org/articles/PMC10120666/
https://europepmc.org/articles/PMC10120666/
Autor:
Sandra Nakandakari-Higa, Maria C. C. Canesso, Sarah Walker, Aleksey Chudnovskiy, Johanne T. Jacobsen, Jana Bilanovic, S. Martina Parigi, Karol Fiedorczuk, Elaine Fuchs, Angelina M. Bilate, Giulia Pasqual, Daniel Mucida, Yuri Pritykin, Gabriel D. Victora
Publikováno v:
bioRxiv
Cellular interactions are essential for tissue organization and functionality. In particular, immune cells rely on direct and usually transient interactions with other immune and non-immune populations to specify and regulate their function. To study
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb5a34e0688be1fb7ea6d4286752e337
https://europepmc.org/articles/PMC10055214/
https://europepmc.org/articles/PMC10055214/
Publikováno v:
Immunity
Pathogenic enteric viruses are a major cause of morbidity and mortality, particularly among children in developing countries. The host response to enteric viruses occurs primarily within the mucosa, where the intestinal immune system must balance pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::205f792a2e27764e787d25c75242461e
https://doi.org/10.1016/j.immuni.2022.04.007
https://doi.org/10.1016/j.immuni.2022.04.007
Autor:
Maria C.C. Canesso, Tiago B.R. Castro, Sandra Nakandakari-Higa, Ainsley Lockhart, Daria Esterházy, Bernardo S. Reis, Gabriel D. Victora, Daniel Mucida
The intestinal immune system must concomitantly tolerate food and commensals and protect against pathogens. Dendritic cells (DCs) orchestrate these immune responses by presenting luminal antigens and inducing functional differentiation of CD4+T cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5ce861e8eba05614c57627ca6b29acb5
https://doi.org/10.1101/2022.10.26.513772
https://doi.org/10.1101/2022.10.26.513772
Autor:
Siqi Liu, Yun Ha Hur, Xin Cai, Qian Cong, Yihao Yang, Chiwei Xu, Angelina M. Bilate, Kevin Andrew Uy Gonzales, Christopher J. Cowley, Brian Hurwitz, Ji-Dung Luo, Tiffany Tseng, Shiri Gur-Cohen, Megan Sribour, Tatiana Omelchenko, John Levorse, Hilda Amalia Pasolli, Craig B. Thompson, Daniel Mucida, Elaine Fuchs
Pathogen infection and tissue injury are universal insults that disrupt homeostasis. Innate immunity senses microbial infections and induces interferons (IFNs) to activate resistance mechanisms. Applying unbiased phylogenetic analysis, we show that i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::36a5f667d1cded4e0358152b1894673b
https://doi.org/10.1101/2022.10.18.509515
https://doi.org/10.1101/2022.10.18.509515
Autor:
Leah A. Gates, Bernardo Sgarbi Reis, Peder J. Lund, Matthew R. Paul, Marylene Leboeuf, Zara Nadeem, Tom S. Carroll, Benjamin A. Garcia, Daniel Mucida, C. David Allis
SUMMARYPosttranslational modifications (PTMs) on histone proteins are a key source of regulation on chromatin through impacting genome organization and important cellular processes, including gene expression. These PTMs often arise from small metabol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f771098e749840d4690b8e3ee171a8b1
https://doi.org/10.1101/2022.09.29.510184
https://doi.org/10.1101/2022.09.29.510184