Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Daniel, McWeeney"'
Autor:
Stephen K. Doberstein, Phi Quach, Kathleen Gogas, Takahiro Miyazaki, Daniel McWeeney, Irene Y. Choi, Jennifer A. Riggs, David Gauvin, Juli Evans, Cherie F. Ali, Juergen W. Pfeiffer, Jonathan Zalevsky, Werner Rubas, Timothy A. Riley, Neel K. Anand, Hema Gursahani, Marlene Hennessy, Grace Kim
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 363(1)
The increasing availability of prescription opioid analgesics for the treatment of pain has been paralleled by an epidemic of opioid misuse, diversion, and overdose. The development of abuse-deterrent formulations (ADFs) of conventional opioids such
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b60ec3d5b31fa337024f90b96e69d05a
https://pubmed.ncbi.nlm.nih.gov/28778859
https://pubmed.ncbi.nlm.nih.gov/28778859
Autor:
Jaehyeon Park, Harlan F Reese, Yun-Chou Tan, Hasim Zecic, Martin Stahl, Keshab Sarma, Renee Litman, Alejandra Trejo, William Bingenheimer, Michael Soth, David Michael Goldstein, Mary Welch, Eric Brian Sjogren, Man-Ling Sung, Sandra Frauchiger, Nolan James Dewdney, Bong San Pablo, Eva Papp, Daniel McWeeney, Ronald J. Hill, Paul Weller, Manjiri Ghate, JoAnn La Fargue, Brian Wong, Stacie A. Dalrymple, James Patrick Dunn, David Mark Rotstein, Richard T. Roberts, Bradford Graves, Rebecca T Suttman, Mcintosh Joel, Farrell Robert P, Andreas Kuglstatter, Chen Jian Jeffrey, Fujun Li, Humberto Bartolome Arzeno, Brad Loe, Tobias Gabriel
Publikováno v:
Journal of Medicinal Chemistry. 54:2255-2265
The development of a new series of p38α inhibitors resulted in the identification of two clinical candidates, one of which was advanced into a phase 2 clinical study for rheumatoid arthritis. The original lead, an lck inhibitor that also potently in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5bdfa3e0a0a96eaca0eea2feab67e249
https://doi.org/10.1021/jm101423y
https://doi.org/10.1021/jm101423y
Autor:
David M, Goldstein, Michael, Soth, Tobias, Gabriel, Nolan, Dewdney, Andreas, Kuglstatter, Humberto, Arzeno, Jeffrey, Chen, William, Bingenheimer, Stacie A, Dalrymple, James, Dunn, Robert, Farrell, Sandra, Frauchiger, JoAnn, La Fargue, Manjiri, Ghate, Bradford, Graves, Ronald J, Hill, Fujun, Li, Renee, Litman, Brad, Loe, Joel, McIntosh, Daniel, McWeeney, Eva, Papp, Jaehyeon, Park, Harlan F, Reese, Richard T, Roberts, David, Rotstein, Bong, San Pablo, Keshab, Sarma, Martin, Stahl, Man-Ling, Sung, Rebecca T, Suttman, Eric B, Sjogren, Yunchou, Tan, Alejandra, Trejo, Mary, Welch, Paul, Weller, Brian R, Wong, Hasim, Zecic
Publikováno v:
Journal of medicinal chemistry. 54(7)
The development of a new series of p38α inhibitors resulted in the identification of two clinical candidates, one of which was advanced into a phase 2 clinical study for rheumatoid arthritis. The original lead, an lck inhibitor that also potently in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::cda31600d6054cc75ed83ea768d5f392
https://pubmed.ncbi.nlm.nih.gov/21375264
https://pubmed.ncbi.nlm.nih.gov/21375264
Autor:
Welch Teresa Rosanne, David Michael Goldstein, Stacie A. Dalrymple, Joann La Fargue, Jay Bertrand, Chakk Ramesha, Michelle F. Browner, Will Tao, Sheila Zipfel, Eva Papp, Alejandra Trejo, Kelly Young, Jose Freire-Moar, James Dunn, Susan Larrabee, Rick Roberts, Mary Welch, Daniel Mcweeney, Armando Villasenor, Jean Marc Lapierre, David Rotstein, On-Yee So, Sharada S. Labadie, Phyllis E. Whiteley, Ken Clifford, Bong San Pablo, Tom Alfredson, Seth Harris, Paul Weller, Eric B. Sjogren, Fujun Li, Francisco X. Mountain View Talamas
Publikováno v:
Journal of medicinal chemistry. 49(5)
A novel class of highly selective inhibitors of p38 MAP kinase was discovered from high throughput screening. The synthesis and optimization of a series of 5-amino-N-phenyl-1H-pyrazol-4-yl-3-phenylmethanones is described. An X-ray crystal structure o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74021732dae7f5fb513dc237543e3952
https://pubmed.ncbi.nlm.nih.gov/16509574
https://pubmed.ncbi.nlm.nih.gov/16509574
Autor:
Abdur Razzaque, Raxit J. Jariwalla, Clinton L. Jones, John T. Brady, Nazma Jahan, Leonard J. Rosenthal, Daniel McWeeney
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 85(15)
To define the morphological transforming region II (mtrII) of human cytomegalovirus (HCMV), a series of subclones of the Xba I/BamHI fragment EM was constructed in vitro and tested for focus-forming activity and tumorigenicity. A 980-base-pair subclo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fdd22256a86491a3734e15b14882d616
https://pubmed.ncbi.nlm.nih.gov/2840673
https://pubmed.ncbi.nlm.nih.gov/2840673