Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Daniel, Mariappa"'
Autor:
Michaela Fenckova, Villo Muha, Daniel Mariappa, Marica Catinozzi, Ignacy Czajewski, Laura E R Blok, Andrew T Ferenbach, Erik Storkebaum, Annette Schenck, Daan M F van Aalten
Publikováno v:
PLoS Genetics, Vol 18, Iss 5, p e1010159 (2022)
O-GlcNAcylation is a reversible co-/post-translational modification involved in a multitude of cellular processes. The addition and removal of the O-GlcNAc modification is controlled by two conserved enzymes, O-GlcNAc transferase (OGT) and O-GlcNAc h
Externí odkaz:
https://doaj.org/article/267272faa05a4b8e9499b0a7286ccd9b
Autor:
Michaela Fenckova, Villo Muha, Daniel Mariappa, Marica Catinozzi, Ignacy Czajewski, Laura E.R. Blok, Andrew T. Ferenbach, Erik Storkebaum, Annette Schenck, Daan M.F. van Aalten
O-GlcNAcylation is a reversible co-/post-translational modification involved in a multitude of cellular processes. The addition and removal of O-GlcNAc modification is controlled by two conserved enzymes, O-GlcNAc transferase (OGT) and O-GlcNAc hydro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::13ae0679cec3b454ef9425b0c9506093
https://doi.org/10.1101/2022.01.10.475726
https://doi.org/10.1101/2022.01.10.475726
Autor:
Daniel Mariappa, Xiaowei Zheng, Marianne Schimpl, Olawale Raimi, Andrew T. Ferenbach, H.-Arno J. Müller, Daan M. F. van Aalten
Publikováno v:
Open Biology, Vol 5, Iss 12 (2015)
Post-translational modification of intracellular proteins with O-linked N-acetylglucosamine (O-GlcNAc) catalysed by O-GlcNAc transferase (OGT) has been linked to regulation of diverse cellular functions. OGT possesses a C-terminal glycosyltransferase
Externí odkaz:
https://doaj.org/article/b94e298faec4481fb80bf832bb42dfae
Autor:
Daniel Mariappa, Andrew T. Ferenbach, Daan M. F. van Aalten, Tonia Aristotelous, Matthias Trost, Nithya Selvan, Ritchie Williamson, David G. Campbell, Robert Gourlay, Iva Hopkins-Navratilova
Publikováno v:
Nat Chem Biol
Protein O-GlcNAcylation is a reversible post-translational modification of serines and threonines on nucleocytoplasmic proteins. It is cycled by the enzymes O-GlcNAc transferase (OGT) and O-GlcNAc hydrolase (O-GlcNAcase or OGA). Genetic approaches in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5a8ac9501ca7a6a6f7f659903e6ce82
https://doi.org/10.1038/nchembio.2404
https://doi.org/10.1038/nchembio.2404
Publikováno v:
The Journal of Biological Chemistry
Post-translational modification of serine/threonine residues in nucleocytoplasmic proteins with GlcNAc (O-GlcNAcylation) is an essential regulatory mechanism in many cellular processes. In Drosophila, null mutants of the Polycomb gene O-GlcNAc transf
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e839414bd1c6efab71594c8c206d7055
https://pubmed.ncbi.nlm.nih.gov/29588363
https://pubmed.ncbi.nlm.nih.gov/29588363
Autor:
Daniel Mariappa, Jana Alonso, Nithya Selvan, Claire A. Shepherd, Iva Navratilova, Andrew T. Ferenbach, Daan M. F. van Aalten, Vladimir S. Borodkin
Publikováno v:
Biochemical Journal. 470:255-262
O-GlcNAcylation is a reversible type of serine/threonine glycosylation on nucleocytoplasmic proteins in metazoa. Various genetic approaches in several animal models have revealed that O-GlcNAcylation is essential for embryogenesis. However, the dynam
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c26a6897210365851d1a48bb20a6e533
https://doi.org/10.1042/bj20150610
https://doi.org/10.1042/bj20150610
Autor:
Michael J. Wolkowicz, Arun Sreekumar, Santosh K. Dasari, Polani B. Seshagiri, Frans A. van der Hoorn, R.H. Aladakatti, Daniel Mariappa
Publikováno v:
Molecular Reproduction and Development. 77:182-193
In mammals, acquisition of fertilization competence of spermatozoa is dependent on the phenomenon of sperm capacitation. One of the critical molecular events of sperm capacitation is protein tyrosine phosphorylation. In a previous study, we demonstra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b9e236f8314fba6c579ed96182d5494b
https://doi.org/10.1002/mrd.21131
https://doi.org/10.1002/mrd.21131
Autor:
Daniel Mariappa, Faina Myachina, H.-Arno J. Müller, Pablo T. Radermacher, Fritz Bosshardt, Christian F. Lehner, Rahul Pandey
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 111(15)
Effects of temperature on biological processes are complex. Diffusion is less affected than the diverse enzymatic reactions that have distinct individual temperature profiles. Hence thermal fluctuations pose a formidable challenge to ectothermic orga
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94fd8cc4a6296feb9bc8b026d050a2fa
https://pubmed.ncbi.nlm.nih.gov/24706800
https://pubmed.ncbi.nlm.nih.gov/24706800
Publikováno v:
The EMBO journal. 32(5)
5‐hydroxy methyl cytosine (5hmC) is a modification identified in vertebrates several decades ago. More recently, a possible role of 5hmC as an epigenetic modifier and/or transcriptional regulator has started to emerge, with altered levels in early
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06e30a771ea1a3008cf73dd474573451
https://pubmed.ncbi.nlm.nih.gov/23403924
https://pubmed.ncbi.nlm.nih.gov/23403924
Autor:
Daniel Mariappa, H.-Arno J. Müller, Karina Mariño, Michael A. J. Ferguson, Ryan Webster, Kathrin Sauert, Daniel C. Turnock, Daan M. F. van Aalten
Glycosylation is essential for growth factor signaling through N-glycosylation of ligands and receptors and the biosynthesis of proteoglycans as co-receptors. Here, we show that protein O-GlcNAcylation is crucial for fibroblast growth factor (FGF) si
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0ade3652e6692ac978b8240ac9c8942
https://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&origin=inward&scp=84255190077
https://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&origin=inward&scp=84255190077