Zobrazeno 1 - 10
of 253
pro vyhledávání: '"Daniel, Hartmann"'
Autor:
Christian Stoess, Yeon-Kyung Choi, Janset Onyuru, Helmut Friess, Hal M. Hoffman, Daniel Hartmann, Ariel E. Feldstein
Publikováno v:
Biomedicines, Vol 12, Iss 3, p 559 (2024)
Cell death is crucial for maintaining tissue balance and responding to diseases. However, under pathological conditions, the surge in dying cells results in an overwhelming presence of cell debris and the release of danger signals. In the liver, this
Externí odkaz:
https://doaj.org/article/9a038d8743d54482831945e945d0ad48
Autor:
Knud Esser, Xiaoming Cheng, Jochen M. Wettengel, Julie Lucifora, Lea Hansen-Palmus, Katharina Austen, Armando A. Roca Suarez, Sarah Heintz, Barbara Testoni, Firat Nebioglu, Minh Tu Pham, Shangqing Yang, Alma Zernecke, Dirk Wohlleber, Marc Ringelhan, Mathias Broxtermann, Daniel Hartmann, Norbert Hüser, Julia Mergner, Andreas Pichlmair, Wolfgang E. Thasler, Mathias Heikenwalder, Georg Gasteiger, Andreas Blutke, Axel Walch, Percy A. Knolle, Ralf Bartenschlager, Ulrike Protzer
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 16, Iss 2, Pp 201-221 (2023)
Background & Aims: A single hepatitis B virus (HBV) particle is sufficient to establish chronic infection of the liver after intravenous injection, suggesting that the virus targets hepatocytes via a highly efficient transport pathway. We therefore i
Externí odkaz:
https://doaj.org/article/9fd675743fc64b5f93ebf586a31ab2ba
Hepatocellular Brg1 promotes CCl4-induced liver inflammation, ECM accumulation and fibrosis in mice.
Autor:
Baocai Wang, Benedikt Kaufmann, Carolin Mogler, Suyang Zhong, Yuhan Yin, Zhangjun Cheng, Roland M Schmid, Helmut Friess, Norbert Hüser, Guido von Figura, Daniel Hartmann
Publikováno v:
PLoS ONE, Vol 18, Iss 11, p e0294257 (2023)
IntroductionHepatic fibrosis is a progressive pathological process involving the exhaustion of hepatocellular regenerative capacity and ultimately leading to the development of cirrhosis and even hepatocellular carcinoma. Brg1, the core subunit of th
Externí odkaz:
https://doaj.org/article/888e4bdaf26d4e89930db833f3af5847
Autor:
Małgorzata Sudacka, Martin Adler, Steven J. Durning, Samuel Edelbring, Ada Frankowska, Daniel Hartmann, Inga Hege, Sören Huwendiek, Monika Sobočan, Nils Thiessen, Felicitas L. Wagner, Andrzej A. Kononowicz
Publikováno v:
BMC Medical Education, Vol 21, Iss 1, Pp 1-10 (2021)
Abstract Background Effective clinical reasoning is a core competency of health professionals that is necessary to assure patients’ safety. Unfortunately, adoption of longitudinal clinical reasoning curricula is still infrequent. This study explore
Externí odkaz:
https://doaj.org/article/3b05ddc02832415d8b81f1bf3431ba62
Autor:
Marcus Brugger, Melanie Laschinger, Sandra Lampl, Annika Schneider, Katrin Manske, Dena Esfandyari, Norbert Hüser, Daniel Hartmann, Katja Steiger, Stefan Engelhardt, Dirk Wohlleber, Percy A. Knolle
Publikováno v:
JHEP Reports, Vol 4, Iss 5, Pp 100465- (2022)
Background & Aims: Increased sensitivity towards tumor necrosis factor (TNF)-induced cell death in virus-infected hepatocytes has revealed a so far unrecognized hepatocyte-intrinsic antiviral immune surveillance mechanism, for which no in vitro or ex
Externí odkaz:
https://doaj.org/article/d30298ff222c47149b68e90c4a9b5176
Autor:
Christian Stöß, Marcella Steffani, Kay Kohlhaw, Claudia Rudroff, Ludger Staib, Daniel Hartmann, Helmut Friess, Michael W. Müller
Publikováno v:
BMC Surgery, Vol 20, Iss 1, Pp 1-9 (2020)
Abstract Background During the first wave of the COVID-19 pandemic, German health care centres were restructured for the treatment of COVID-19 patients. This was accompanied by the suspension of the surgical programme. The aim of the survey was to de
Externí odkaz:
https://doaj.org/article/3ff8b95a99264797879ef1417a73e6d2
Autor:
Karim Hamesch, Nurdan Guldiken, Mahmoud Aly, Norbert Hüser, Daniel Hartmann, Pierre Rufat, Marianne Ziol, Katharina Remih, Georg Lurje, Bernhard Scheiner, Christian Trautwein, Mattias Mandorfer, Thomas Reiberger, Sebastian Mueller, Tony Bruns, Pierre Nahon, Pavel Strnad
Publikováno v:
BMC Medicine, Vol 18, Iss 1, Pp 1-12 (2020)
Abstract Background Keratins (Ks) represent tissue-specific proteins. K18 is produced in hepatocytes while K19, the most widely used ductular reaction (DR) marker, is found in cholangiocytes and hepatic progenitor cells. K18-based serum fragments are
Externí odkaz:
https://doaj.org/article/fbbf0c3b59154001abc9f9ec40dff6ce
Autor:
Miao Lu, Daniel Hartmann, Rickmer Braren, Aayush Gupta, Baocai Wang, Yang Wang, Carolin Mogler, Zhangjun Cheng, Thomas Wirth, Helmut Friess, Jörg Kleeff, Norbert Hüser, Yoshiaki Sunami
Publikováno v:
BMC Cancer, Vol 19, Iss 1, Pp 1-13 (2019)
Abstract Background Hepatocellular carcinoma (HCC) is the most prevalent primary liver cancer, accounting for 80–90% of cases. Mutations are commonly found in the signaling regulating the PI3K/Akt pathway, leading to oncogenic cell proliferation an
Externí odkaz:
https://doaj.org/article/8db8d73d6eec464192da89ca28cd6563
Autor:
Yuhan Yin, Anna Sichler, Josef Ecker, Melanie Laschinger, Gerhard Liebisch, Marcus Höring, Marijana Basic, André Bleich, Xue-Jun Zhang, Ludwig Kübelsbeck, Johannes Plagge, Emely Scherer, Dirk Wohlleber, Jianye Wang, Yang Wang, Marcella Steffani, Pavel Stupakov, Yasmin Gärtner, Fabian Lohöfer, Carolin Mogler, Helmut Friess, Daniel Hartmann, Bernhard Holzmann, Norbert Hüser, Klaus-Peter Janssen
Publikováno v:
Journal of Hepatology. 78:820-835
Autor:
Ulrich Nitsche, Constance Weber, Benedikt Kaufmann, Guido von Figura, Volker Assfalg, Gregor Miller, Helmut Friess, Norbert Hüser, Daniel Hartmann
Publikováno v:
Data in Brief, Vol 31, Iss , Pp 105973- (2020)
Between 2007 and 2016, 140 consecutive patients who underwent resection of colorectal cancer with simultaneous liver metastases at a single university hospital were retrospectively analysed. In order to gather information regarding potential survival
Externí odkaz:
https://doaj.org/article/172348f2ee6449eaa0f781d2a1760728