Zobrazeno 1 - 10
of 729
pro vyhledávání: '"Daniel, H Geschwind"'
Autor:
Adam Pavlinek, Dwaipayan Adhya, Alex Tsompanidis, Varun Warrier, Anthony C. Vernon, Madeline Lancaster, Jonathan Mill, Deepak P. Srivastava, Simon Baron-Cohen, Carrie Allison, Rosie Holt, Paula Smith, Tracey Parsons, Joanna Davis, Matthew Hassall, Daniel H. Geschwind, Alexander EP. Heazell, Alice Franklin, Rosie Bamford, Jonathan Davies, Matthew E. Hurles, Hilary C. Martin, Mahmoud Mousa, David H. Rowitch, Kathy K. Niakan, Graham J. Burton, Fateneh Ghafari, Lucia Dutan-Polit, Madeline A. Lancaster, Ilaria Chiaradia, Tal Biron-Shental, Lidia V. Gabis
Publikováno v:
Biological Psychiatry Global Open Science, Vol 4, Iss 5, Pp 100343- (2024)
Sex differences are widespread during neurodevelopment and play a role in neuropsychiatric conditions such as autism, which is more prevalent in males than females. In humans, males have been shown to have larger brain volumes than females with devel
Externí odkaz:
https://doaj.org/article/696dcf6345f647389e6fcc214263b982
Autor:
Ryan Passino, Matthew C. Finneran, Hannah Hafner, Qian Feng, Lucas D. Huffman, Xiao-Feng Zhao, Craig N. Johnson, Riki Kawaguchi, Juan A. Oses-Prieto, Alma L. Burlingame, Daniel H. Geschwind, Larry I. Benowitz, Roman J. Giger
Publikováno v:
Cell Reports, Vol 43, Iss 3, Pp 113931- (2024)
Summary: In adult mammals, injured retinal ganglion cells (RGCs) fail to spontaneously regrow severed axons, resulting in permanent visual deficits. Robust axon growth, however, is observed after intra-ocular injection of particulate β-glucan isolat
Externí odkaz:
https://doaj.org/article/292ce40fd6534ad8ac191a8ef34cab42
Autor:
Konrad Wagstyl, Sophie Adler, Jakob Seidlitz, Simon Vandekar, Travis T Mallard, Richard Dear, Alex R DeCasien, Theodore D Satterthwaite, Siyuan Liu, Petra E Vértes, Russell T Shinohara, Aaron Alexander-Bloch, Daniel H Geschwind, Armin Raznahan
Publikováno v:
eLife, Vol 12 (2024)
The cerebral cortex underlies many of our unique strengths and vulnerabilities, but efforts to understand human cortical organization are challenged by reliance on incompatible measurement methods at different spatial scales. Macroscale features such
Externí odkaz:
https://doaj.org/article/53c392b8d0c449c5b682ca99e6adbe03
Autor:
Ruth Johnson, Yi Ding, Vidhya Venkateswaran, Arjun Bhattacharya, Kristin Boulier, Alec Chiu, Sergey Knyazev, Tommer Schwarz, Malika Freund, Lingyu Zhan, Kathryn S. Burch, Christa Caggiano, Brian Hill, Nadav Rakocz, Brunilda Balliu, Christopher T. Denny, Jae Hoon Sul, Noah Zaitlen, Valerie A. Arboleda, Eran Halperin, Sriram Sankararaman, Manish J. Butte, UCLA Precision Health Data Discovery Repository Working Group, UCLA Precision Health ATLAS Working Group, Clara Lajonchere, Daniel H. Geschwind, Bogdan Pasaniuc
Publikováno v:
Genome Medicine, Vol 14, Iss 1, Pp 1-4 (2022)
Externí odkaz:
https://doaj.org/article/ad5c392dbf0848289645230e7e7aa62c
Autor:
Sree Deepthi Muthukrishnan, Riki Kawaguchi, Pooja Nair, Rachna Prasad, Yue Qin, Maverick Johnson, Qing Wang, Nathan VanderVeer-Harris, Amy Pham, Alvaro G. Alvarado, Michael C. Condro, Fuying Gao, Raymond Gau, Maria G. Castro, Pedro R. Lowenstein, Arjun Deb, Jason D. Hinman, Frank Pajonk, Terry C. Burns, Steven A. Goldman, Daniel H. Geschwind, Harley I. Kornblum
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-19 (2022)
Therapeutic stress induces phenotypic plasticity in glioma stem cells although the mechanisms underlying this remain poorly understood. Here, the authors show that P300 mediates the radiation-induced vascular-like conversion of glioma stem cells to p
Externí odkaz:
https://doaj.org/article/2f813af486a84bc6939ddacebcf2e7f8
Autor:
Ngan Pan Bennett Au, Gajendra Kumar, Pallavi Asthana, Fuying Gao, Riki Kawaguchi, Raymond Chuen Chung Chang, Kwok Fai So, Yang Hu, Daniel H. Geschwind, Giovanni Coppola, Chi Him Eddie Ma
Publikováno v:
npj Regenerative Medicine, Vol 7, Iss 1, Pp 1-16 (2022)
Abstract Adult mammalian injured axons regenerate over short-distance in the peripheral nervous system (PNS) while the axons in the central nervous system (CNS) are unable to regrow after injury. Here, we demonstrated that Lycium barbarum polysacchar
Externí odkaz:
https://doaj.org/article/59d7549c2a1b4038917bf05b09f9ef36
Autor:
Jing-Ping Lin, Hannah M. Kelly, Yeajin Song, Riki Kawaguchi, Daniel H. Geschwind, Steven Jacobson, Daniel S. Reich
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-21 (2022)
Studies of cell heterogeneity in white matter in primates have been limited to date. Here the authors describe a marmoset brain cell atlas that bridges rodent and human data, revealing strong gray-white matter glial segregation.
Externí odkaz:
https://doaj.org/article/5acbadad11ce435dbd202e080adc66cb
Autor:
Ruth Johnson, Yi Ding, Vidhya Venkateswaran, Arjun Bhattacharya, Kristin Boulier, Alec Chiu, Sergey Knyazev, Tommer Schwarz, Malika Freund, Lingyu Zhan, Kathryn S. Burch, Christa Caggiano, Brian Hill, Nadav Rakocz, Brunilda Balliu, Christopher T. Denny, Jae Hoon Sul, Noah Zaitlen, Valerie A. Arboleda, Eran Halperin, Sriram Sankararaman, Manish J. Butte, UCLA Precision Health Data Discovery Repository Working Group, UCLA Precision Health ATLAS Working Group, Clara Lajonchere, Daniel H. Geschwind, Bogdan Pasaniuc
Publikováno v:
Genome Medicine, Vol 14, Iss 1, Pp 1-23 (2022)
Abstract Background Large medical centers in urban areas, like Los Angeles, care for a diverse patient population and offer the potential to study the interplay between genetic ancestry and social determinants of health. Here, we explore the implicat
Externí odkaz:
https://doaj.org/article/fd788f179452445180d03f6817e0c20b
Autor:
Yuyan Cheng, Yuqin Yin, Alice Zhang, Alexander M. Bernstein, Riki Kawaguchi, Kun Gao, Kyra Potter, Hui-Ya Gilbert, Yan Ao, Jing Ou, Catherine J. Fricano-Kugler, Jeffrey L. Goldberg, Zhigang He, Clifford J. Woolf, Michael V. Sofroniew, Larry I. Benowitz, Daniel H. Geschwind
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-22 (2022)
Here the authors couple an integrative genomic analysis with substantial in vitro and in vivo experimental validation, identifying REST as a novel suppressor of a pro-regenerative gene program and CNS axon regeneration in mice.
Externí odkaz:
https://doaj.org/article/df6521e5d58e42ea8efb14302c66060b
Autor:
Stefano Berto, Alex H. Treacher, Emre Caglayan, Danni Luo, Jillian R. Haney, Michael J. Gandal, Daniel H. Geschwind, Albert A. Montillo, Genevieve Konopka
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-11 (2022)
Gene expression patterns have been associated with functional activity patterns in the brain. Here the authors determine how gene expression patterns in the human brain supports brain phenotypes obtained from resting state fMRI imaging, identifying b
Externí odkaz:
https://doaj.org/article/c0365749565041e9b1397c72558560d0