Zobrazeno 1 - 10
of 106
pro vyhledávání: '"Daniel, Gitler"'
Autor:
Alexandra Stavsky, Leonardo A Parra-Rivas, Shani Tal, Jen Riba, Kayalvizhi Madhivanan, Subhojit Roy, Daniel Gitler
Publikováno v:
eLife, Vol 12 (2024)
The cytosolic proteins synucleins and synapsins are thought to play cooperative roles in regulating synaptic vesicle (SV) recycling, but mechanistic insight is lacking. Here, we identify the synapsin E-domain as an essential functional binding-partne
Externí odkaz:
https://doaj.org/article/54c49400ea3b46eb8987578b70d988d8
Autor:
Alexandra Stavsky, Ohad Stoler, Marko Kostic, Tomer Katoshevsky, Essam A. Assali, Ivana Savic, Yael Amitai, Holger Prokisch, Steffen Leiz, Cornelia Daumer-Haas, Ilya Fleidervish, Fabiana Perrochi, Daniel Gitler, Israel Sekler
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-14 (2021)
Stavsky et al. examined the effects of deleting the mitochondrial sodium/lithium/calcium exchanger, NCLX, on mitochondrial and synaptic calcium homeostasis, synaptic activity, and plasticity in mice. Having identified a human mutation that impairs NC
Externí odkaz:
https://doaj.org/article/f0e2c7e570da4222b9804930f469cda4
Autor:
Ohad Stoler, Alexandra Stavsky, Yana Khrapunsky, Israel Melamed, Grace Stutzmann, Daniel Gitler, Israel Sekler, Ilya Fleidervish
Publikováno v:
eLife, Vol 11 (2022)
Mitochondrial activity is crucial for the plasticity of central synapses, but how the firing pattern of pre- and postsynaptic neurons affects the mitochondria remains elusive. We recorded changes in the fluorescence of cytosolic and mitochondrial Ca2
Externí odkaz:
https://doaj.org/article/fa37d91590f94efc99cae25f5be82c10
Autor:
Mohamad-Reza Aghanoori, Vicky Margulets, Darrell R. Smith, Lorrie A. Kirshenbaum, Daniel Gitler, Paul Fernyhough
Publikováno v:
Molecular Metabolism, Vol 49, Iss , Pp 101191- (2021)
Objective: The distal dying-back of the longest nerve fibres is a hallmark of diabetic neuropathy, and impaired provision of energy in the form of adenosine triphosphate (ATP) may contribute to this neurodegenerative process. We hypothesised that ene
Externí odkaz:
https://doaj.org/article/79dd1362964d46b197d74b86ae530902
Autor:
Alexandra Stavsky, Ohad Stoler, Marko Kostic, Tomer Katoshevsky, Essam A. Assali, Ivana Savic, Yael Amitai, Holger Prokisch, Steffen Leiz, Cornelia Daumer-Haas, Ilya Fleidervish, Fabiana Perocchi, Daniel Gitler, Israel Sekler
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-1 (2021)
Externí odkaz:
https://doaj.org/article/71dbc48b81ff44bf90112ee9c7bd576d
Autor:
Robert Mertens, Sarah Melchert, Daniel Gitler, Morten Brix Schou, Sverre Georg Saether, Arne Vaaler, Johannes Piepgras, Elena Kochova, Fabio Benfenati, Gudrun Ahnert-Hilger, Klemens Ruprecht, Markus Höltje
Publikováno v:
PLoS ONE, Vol 13, Iss 12, p e0208636 (2018)
OBJECTIVE:To identify the specific domains of the presynaptic protein synapsin targeted by recently described autoantibodies to synapsin. METHODS:Sera of 20 and CSF of two patients with different psychiatric and neurological disorders previously test
Externí odkaz:
https://doaj.org/article/833d4de0ee774980bed0575f86294ac5
Autor:
Tomer Katoshevsky, Fabiana Perocchi, Daniel Gitler, Essam A. Assali, Steffen Leiz, Ohad Stoler, Marko Kostic, Yael Amitai, Ilya A. Fleidervish, Ivana Savic, Israel Sekler, Alexandra Stavsky, Holger Prokisch, Cornelia Daumer-Haas
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-14 (2021)
Comm. Biol. 4:666 (2021)
Communications Biology
Comm. Biol. 4:666 (2021)
Communications Biology
Calcium dynamics control synaptic transmission. Calcium triggers synaptic vesicle fusion, determines release probability, modulates vesicle recycling, participates in long-term plasticity and regulates cellular metabolism. Mitochondria, the main sour
Autor:
Alexandra Stavsky, Ohad Stoler, Yana Khrapunsky, Israel Melamed, Grace Stutzmann, Daniel Gitler, Israel Sekler, Ilya Fleidervish
Publikováno v:
eLife. 11
Mitochondrial activity is crucial for the plasticity of central synapses, but how the firing pattern of pre- and postsynaptic neurons affects the mitochondria remains elusive. We recorded changes in the fluorescence of cytosolic and mitochondrial Ca2
Autor:
Ohad, Stoler, Alexandra, Stavsky, Yana, Khrapunsky, Israel, Melamed, Grace, Stutzmann, Daniel, Gitler, Israel, Sekler, Ilya, Fleidervish
Publikováno v:
eLife. 11
Mitochondrial activity is crucial for the plasticity of central synapses, but how the firing pattern of pre- and postsynaptic neurons affects the mitochondria remains elusive. We recorded changes in the fluorescence of cytosolic and mitochondrial Ca
Autor:
Fabiana Perocchi, Ivana Savic, Steffen Leiz, Tomer Katoshevsky, Cornelia Daumer-Haas, Daniel Gitler, Yael Amitai, Essam A. Assali, Israel Sekler, Ohad Stoler, Marko Kostic, Holger Prokisch, Alexandra Stavsky, Ilya A. Fleidervish
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-1 (2021)
Communications Biology
Communications Biology
Calcium dynamics control synaptic transmission. Calcium triggers synaptic vesicle fusion, determines release probability, modulates vesicle recycling, participates in long-term plasticity and regulates cellular metabolism. Mitochondria, the main sour