Zobrazeno 1 - 10
of 169
pro vyhledávání: '"Daniel, Christ"'
Autor:
Romain Rouet, Jake Y. Henry, Matt D. Johansen, Meghna Sobti, Harikrishnan Balachandran, David B. Langley, Gregory J. Walker, Helen Lenthall, Jennifer Jackson, Stephanie Ubiparipovic, Ohan Mazigi, Peter Schofield, Deborah L. Burnett, Simon H. J. Brown, Marianne Martinello, Bernard Hudson, Nicole Gilroy, Jeffrey J. Post, Anthony Kelleher, Hans-Martin Jäck, Christopher C. Goodnow, Stuart G. Turville, William D. Rawlinson, Rowena A. Bull, Alastair G. Stewart, Philip M. Hansbro, Daniel Christ
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-13 (2023)
Here, Rouet et al. present a strategy for the identification of broadly neutralising antibodies against SARS-CoV-2 receptor binding domain from peripheral blood mononuclear cells of convalescent patients, which enabled the identification of a new cla
Externí odkaz:
https://doaj.org/article/d7c35bcc59bc4a9fb845343c96f9aa30
Autor:
Chansavath Phetsouphanh, Weng Hua Khoo, Katherine Jackson, Vera Klemm, Annett Howe, Anupriya Aggarwal, Anouschka Akerman, Vanessa Milogiannakis, Alberto Ospina Stella, Romain Rouet, Peter Schofield, Megan L. Faulks, Hannah Law, Thidarat Danwilai, Mitchell Starr, C. Mee Ling Munier, Daniel Christ, Mandeep Singh, Peter I. Croucher, Fabienne Brilot-Turville, Stuart Turville, Tri Giang Phan, Gregory J. Dore, David Darley, Philip Cunningham, Gail V. Matthews, Anthony D. Kelleher, John J. Zaunders
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
BackgroundLong-term immunity to SARS-CoV-2 infection, including neutralizing antibodies and T cell-mediated immunity, is required in a very large majority of the population in order to reduce ongoing disease burden.MethodsWe have investigated the ass
Externí odkaz:
https://doaj.org/article/54f0e1950fa84edf8548d013da07f7a4
Autor:
Anupriya Aggarwal, Anouschka Akerman, Vanessa Milogiannakis, Mariana Ruiz Silva, Gregory Walker, Alberto Ospina Stella, Andrea Kindinger, Thomas Angelovich, Emily Waring, Supavadee Amatayakul-Chantler, Nathan Roth, Sandro Manni, Thomas Hauser, Thomas Barnes, Anna Condylios, Malinna Yeang, Maureen Wong, Tyra Jean, Charles S.P. Foster, Daniel Christ, Alexandra Carey Hoppe, Mee Ling Munier, David Darley, Melissa Churchill, Damien J. Stark, Gail Matthews, William D. Rawlinson, Anthony D. Kelleher, Stuart G. Turville
Publikováno v:
EBioMedicine, Vol 84, Iss , Pp 104270- (2022)
Summary: Background: Genetically distinct viral variants of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) have been recorded since January 2020. The introduction of global vaccine programs has contributed to lower COVID-19 hospitalisat
Externí odkaz:
https://doaj.org/article/be39014e806640b7a9df0f3942d859a8
Autor:
Julien Solinc, Jessica Raimbault‐Machado, France Dierick, Lamiaa El Bernoussi, Ly Tu, Raphaël Thuillet, Nathalie Mougenot, Bénédicte Hoareau‐Coudert, Virginie Monceau, Catherine Pavoine, Fabrice Atassi, David Sassoon, Giovanna Marazzi, Richard P. Harvey, Peter Schofield, Daniel Christ, Marc Humbert, Christophe Guignabert, Florent Soubrier, Sophie Nadaud
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 11, Iss 7 (2022)
Background Platelet‐derived growth factor is a major regulator of the vascular remodeling associated with pulmonary arterial hypertension. We previously showed that protein widely 1 (PW1+) vascular progenitor cells participate in early vessel neomu
Externí odkaz:
https://doaj.org/article/81cbbe521b80430db80a86d9c5326839
Autor:
Harikrishnan Balachandran, Chansavath Phetsouphanh, David Agapiou, Anurag Adhikari, Chaturaka Rodrigo, Mohamed Hammoud, Lok Bahadur Shrestha, Elizabeth Keoshkerian, Money Gupta, Stuart Turville, Daniel Christ, Cecile King, Sarah C. Sasson, Adam Bartlett, Branka Grubor-Bauk, William Rawlinson, Anupriya Aggarwal, Alberto Ospina Stella, Vera Klemm, Michael M. Mina, Jeffrey J. Post, Bernard Hudson, Nicky Gilroy, Pam Konecny, Golo Ahlenstiel, Dominic E. Dwyer, Tania C. Sorrell, Anthony Kelleher, Nicodemus Tedla, Andrew R. Lloyd, Marianne Martinello, Rowena A. Bull
Publikováno v:
Cell Reports, Vol 38, Iss 6, Pp 110345- (2022)
Summary: Understanding the long-term maintenance of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) immunity is critical for predicting protection against reinfection. In an age- and gender-matched cohort of 24 participants, the associat
Externí odkaz:
https://doaj.org/article/d1686078a040413a867cbc08aa5e8b00
Autor:
Man-Tat Lau, Shila Ghazanfar, Ashleigh Parkin, Angela Chou, Jourdin R. Rouaen, Jamie B. Littleboy, Danielle Nessem, Thang M. Khuong, Damien Nevoltris, Peter Schofield, David Langley, Daniel Christ, Jean Yang, Marina Pajic, G. Gregory Neely
Publikováno v:
Genome Biology, Vol 21, Iss 1, Pp 1-12 (2020)
Abstract Background Drug resistance is a major obstacle in cancer therapy. To elucidate the genetic factors that regulate sensitivity to anti-cancer drugs, we performed CRISPR-Cas9 knockout screens for resistance to a spectrum of drugs. Results In ad
Externí odkaz:
https://doaj.org/article/c47471a679ca416996391ad2844c7411
Autor:
Fernando Y Maeda, Jurriaan JH van Haaren, David B Langley, Daniel Christ, Norma W Andrews, Wenxia Song
Publikováno v:
eLife, Vol 10 (2021)
B-cell receptor (BCR)-mediated antigen internalization and presentation are essential for humoral memory immune responses. Antigen encountered by B-cells is often tightly associated with the surface of pathogens and/or antigen-presenting cells. Inter
Externí odkaz:
https://doaj.org/article/1c77923d23a442de8b9aa7e64904b956
Autor:
Fiona Tea, Alberto Ospina Stella, Anupriya Aggarwal, David Ross Darley, Deepti Pilli, Daniele Vitale, Vera Merheb, Fiona X Z Lee, Philip Cunningham, Gregory J Walker, Christina Fichter, David A Brown, William D Rawlinson, Sonia R Isaacs, Vennila Mathivanan, Markus Hoffmann, Stefan Pöhlman, Ohan Mazigi, Daniel Christ, Dominic E Dwyer, Rebecca J Rockett, Vitali Sintchenko, Veronica C Hoad, David O Irving, Gregory J Dore, Iain B Gosbell, Anthony D Kelleher, Gail V Matthews, Fabienne Brilot, Stuart G Turville
Publikováno v:
PLoS Medicine, Vol 18, Iss 7, p e1003656 (2021)
The Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) antibody neutralization response and its evasion by emerging viral variants and variant of concern (VOC) are unknown, but critical to understand reinfection risk and breakthrough infect
Externí odkaz:
https://doaj.org/article/9d1dac9be74d4ec29e5d0a3a9bd84bf7
Autor:
Claire Vennin, Pauline Mélénec, Romain Rouet, Max Nobis, Aurélie S. Cazet, Kendelle J. Murphy, David Herrmann, Daniel A. Reed, Morghan C. Lucas, Sean C. Warren, Zehra Elgundi, Mark Pinese, Gabriella Kalna, Daniel Roden, Monisha Samuel, Anaiis Zaratzian, Shane T. Grey, Andrew Da Silva, Wilfred Leung, Australian Pancreatic Genome Initiative (APGI), Suresh Mathivanan, Yingxiao Wang, Anthony W. Braithwaite, Daniel Christ, Ales Benda, Ashleigh Parkin, Phoebe A. Phillips, John M. Whitelock, Anthony J. Gill, Owen J. Sansom, David R. Croucher, Benjamin L. Parker, Marina Pajic, Jennifer P. Morton, Thomas R. Cox, Paul Timpson
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-22 (2019)
Subtypes of cancer associated fibroblasts can both promote and suppress tumorigenesis. Here, the authors investigate how p53 status in pancreatic cancer cells affects their interaction with cancer associated fibroblasts, and report perlecan as a medi
Externí odkaz:
https://doaj.org/article/9cbe7f002204495db0cd437d4360e24c
Autor:
Sacha Zinn, Rodrigo Vazquez-Lombardi, Carsten Zimmermann, Puja Sapra, Lutz Jermutus, Daniel Christ
Publikováno v:
Nature Cancer. 4:165-180