Tucatinib plus trastuzumab for chemotherapy-refractory, HER2-positive, RAS wild-type unresectable or metastatic colorectal cancer (MOUNTAINEER): a multicentre, open-label, phase 2 study

Autor: John H Strickler, Andrea Cercek, Salvatore Siena, Thierry André, Kimmie Ng, Eric Van Cutsem, Christina Wu, Andrew S Paulson, Joleen M Hubbard, Andrew L Coveler, Christos Fountzilas, Adel Kardosh, Pashtoon M Kasi, Heinz-Josef Lenz, Kristen K Ciombor, Elena Elez, David L Bajor, Chiara Cremolini, Federico Sanchez, Michael Stecher, Wentao Feng, Tanios S Bekaii-Saab, Marc Peeters, Marc Van den Evnde, Christophe Borg, Matthieu Sarabi, Francois Ghiringhelli, Benoist Chibaudel, Maria G. Zampino, Susana R. Keranen, Ramon Salazar, Pilar Alfonso, John H. Strickler, Andrew S. Paulson, Joleen M. Hubbard, Andrew L. Coveler, Pashtoon M. Kasi, Kristen K. Ciombor, David L. Bajor, Tanios S. Bekaii-Saab, Olumide Gbolahan, Patrick Boland, Daniel Berg, Timothy Goggins, Anwar Saeed, Howard Burris, Johanna Bendell, Darryl Outlaw, Isaac Tafur, Ardaman Shergill, Daniel Catenacci, Jun Gong, Ignacio Garrido-Laguna, Gene Finley, Benjamin Weinberg, Anthony Shields, Philip Philip, Anita Turk, Anthony Nguyen, Fadi Braiteh, Vijay Patel, William Harwin, Ian Anderson, Ajay Kundra, Christopher Chen, James Ford, Madappa Kundranda, Danny Nguyen, Suresh Ratnam, Donald Richards, Sujatha Nallapareddy, Sridhar Beeram, Scott McKenney, Spencer Shao

Publikováno v: The Lancet Oncology. 24:496-508

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::7adfd2ad44d4d2c2a9c7ef887cf177ac
https://doi.org/10.1016/s1470-2045(23)00150-x

ACR Appropriateness Criteria® Staging and Follow-Up of Esophageal Cancer

Autor: Constantine A. Raptis, Alan Goldstein, Travis S. Henry, Kristin K. Porter, Daniel Catenacci, Aine Marie Kelly, Christopher T. Kuzniewski, Andrew R. Lai, Elizabeth Lee, Jason M. Long, Maria D. Martin, Michael F. Morris, Kim L. Sandler, Arlene Sirajuddin, Devaki Shilpa Surasi, Graham W. Wallace, Ihab R. Kamel, Edwin F. Donnelly

Publikováno v: Journal of the American College of Radiology. 19:S462-S472

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3455f09247edf57383554037bcad66b8
https://doi.org/10.1016/j.jacr.2022.09.008

Abstract CT015: Safety and efficacy of TTX-030, an anti-CD39 antibody, in combination with chemoimmunotherapy for the first line treatment of locally advanced or metastatic gastric/GEJ cancer

Autor: Zev Wainberg, Yoon-Koo Kang, Keun-Wook Lee, Seung Tae Kim, Joseph Chao, Daniel Catenacci, Sung Yong Oh, Heloisa P. Soares, J. Eva Selfridge, Yongjun Cha, Roland T. Skeel, Hyung-Don Kim, Anh Tran, Achim Moesta, Tracy Dela Cruz, Anil Singhal, Thomas M. Jahn, Farshid Dayyani

Publikováno v: Cancer Research. 82:CT015-CT015

Background: The ecto-ATPase CD39 is the rate-limiting enzyme in the adenosine pathway that plays an important immune regulatory role. Preclinically, inhibition of CD39 by TTX-030, a first-in-class fully human anti-CD39 antibody, reversed immunosuppre

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b5b26898f67f9e8d47a26563d047b764
https://doi.org/10.1158/1538-7445.am2022-ct015

Biliary cancer: Utility of next-generation sequencing for clinical management

Autor: Milind, Javle, Tanios, Bekaii-Saab, Apurva, Jain, Ying, Wang, Robin Katie, Kelley, Kai, Wang, Hyunseon C, Kang, Daniel, Catenacci, Siraj, Ali, Sunil, Krishnan, Daniel, Ahn, Andrea Grace, Bocobo, Mingxin, Zuo, Ahmed, Kaseb, Vincent, Miller, Philip J, Stephens, Funda, Meric-Bernstam, Rachna, Shroff, Jeffrey, Ross

Publikováno v: Cancer. 122(24)

Biliary tract cancers (BTCs) typically present at an advanced stage, and systemic chemotherapy is often of limited benefit.Hybrid capture-based comprehensive genomic profiling (CGP) was performed for 412 intrahepatic cholangiocarcinomas (IHCCAs), 57

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::f8d2a1f21c3a423a8505cd6fcb99d6eb
https://pubmed.ncbi.nlm.nih.gov/27622582

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