Zobrazeno 1 - 10
of 591
pro vyhledávání: '"Daniel, Castellano"'
Autor:
Daniel Castellano-Castillo, Bruno Ramos-Molina, María Dolores Frutos, Isabel Arranz-Salas, Armando Reyes-Engel, María Isabel Queipo-Ortuño, Fernando Cardona
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 174, Iss , Pp 116508- (2024)
Non-alcoholic fatty liver disease (NAFLD) is a growing health problem due to the increased obesity rates, among other factors. In its more severe stage (NASH), inflammation, hepatocellular ballooning and fibrosis are present in the liver, which can f
Externí odkaz:
https://doaj.org/article/9a415c508394440382de897e345cddff
Autor:
Do-Youn Oh, Maria Alsina Maqueda, David I. Quinn, Peter J. O’Dwyer, Ian Chau, Sun Young Kim, Ignacio Duran, Daniel Castellano, Jordan Berlin, Begona Mellado, Stephen K. Williamson, Keun-Wook Lee, Francisca Marti, Paul Mathew, Muhammad Wasif Saif, Ding Wang, Elizabeth Chong, Jacqueline Hilger-Rolfe, James P. Dean, Hendrik-Tobias Arkenau
Publikováno v:
BMC Cancer, Vol 23, Iss 1, Pp 1-14 (2023)
Abstract Background Ibrutinib, a first-in-class inhibitor of Bruton’s tyrosine kinase, is approved for the treatment of various B-cell malignancies and chronic graft-versus-host disease. Based on encouraging preclinical data, safety and efficacy of
Externí odkaz:
https://doaj.org/article/1fe44534f0e94c6a89809b887b29866b
Autor:
Elisabeth G. E. deVries, Josef Rüschoff, Martijn Lolkema, Josep Tabernero, Luca Gianni, Emile Voest, Derk Jan A. deGroot, Daniel Castellano, Gilles Erb, Julia Naab, Margarita Donica, Regula Deurloo, Michiel S. van derHeijden, Giuseppe Viale
Publikováno v:
Cancer Medicine, Vol 12, Iss 11, Pp 12071-12083 (2023)
Abstract The antibody‐drug conjugate trastuzumab emtansine (T‐DM1) is approved for human epidermal growth factor receptor 2 (HER2/ERBB2)–positive breast cancer. We aimed to study tumor HER2 expression and its effects on T‐DM1 responses in pat
Externí odkaz:
https://doaj.org/article/0f7c9c9a50584cb282318c9ac1965648
Publikováno v:
El Ágora USB, Vol 22, Iss 2, Pp 567-581 (2023)
Las principales posturas teóricas que han abordado la situación de la escuela rural en el marco del conflicto armado en Colombia presenten comprensiones homogéneas sobre la escuela rural que refuerzan una idea precaria de esta y justifican su abor
Externí odkaz:
https://doaj.org/article/96718adb4afe420fb871026a642cb8a5
Autor:
Eva Galle, Chee-Wai Wong, Adhideb Ghosh, Thibaut Desgeorges, Kate Melrose, Laura C. Hinte, Daniel Castellano-Castillo, Magdalena Engl, Joao Agostinho de Sousa, Francisco Javier Ruiz-Ojeda, Katrien De Bock, Jonatan R. Ruiz, Ferdinand von Meyenn
Publikováno v:
Genome Biology, Vol 23, Iss 1, Pp 1-28 (2022)
Abstract Background Histone lactylation has been recently described as a novel histone post-translational modification linking cellular metabolism to epigenetic regulation. Results Given the expected relevance of this modification and current limited
Externí odkaz:
https://doaj.org/article/c9ecdc1a92de4e0786206a8879e43b67
Akademický článek
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Autor:
Albert Font, Montserrat Domenech, Jose Luis Ramirez, Miriam Marqués, Raquel Benítez, Vicenç Ruiz de Porras, José L. Gago, Cristina Carrato, Francesc Sant, Hector Lopez, Daniel Castellano, Nuria Malats, M. Luz Calle, Francisco X. Real
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
Background and objectiveNeoadjuvant chemotherapy (NAC) followed by cystectomy is the standard of care in muscle-invasive bladder cancer (MIBC). Pathological response has been associated with longer survival, but no currently available clinicopatholog
Externí odkaz:
https://doaj.org/article/d5f1dbc0eda140979411c776bbf1ff57
Autor:
Michiel S. van der Heijden, Thomas Powles, Daniel Petrylak, Ronald de Wit, Andrea Necchi, Cora N. Sternberg, Nobuaki Matsubara, Hiroyuki Nishiyama, Daniel Castellano, Syed A. Hussain, Aristotelis Bamias, Georgios Gakis, Jae-Lyun Lee, Scott T. Tagawa, Ulka Vaishampayan, Jeanny B. Aragon-Ching, Bernie J. Eigl, Rebecca R. Hozak, Erik R. Rasmussen, Meng Summer Xia, Ryan Rhodes, Sameera Wijayawardana, Katherine M. Bell-McGuinn, Amit Aggarwal, Alexandra Drakaki
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-15 (2022)
Identification of biomarkers to stratify patients who might benefit from treatment is needed to optimize targeted therapies. Here, based on an analysis of the RANGE trial (NCT02426125), the authors report potentially predictive biomarkers for surviva
Externí odkaz:
https://doaj.org/article/48cfab2e04994935a36166abe99febbf
Autor:
Ernest Choy, Yohann Loriot, Fabio Calabrò, Cora N Sternberg, Guillermo De Velasco, Daniel Castellano, Roubini Zakopoulou, Aristotelis Bamias, Nicholas James, Axel Merseburger, F Lopez-Rios, Mario Kramer, Kimon Tzannis
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss 1 (2023)
Background Bellmunt Risk Score, based on Eastern Cooperative Oncology Group (ECOG) performance status (PS), hemoglobin levels and presence of liver metastases, is the most established prognostic algorithm for patients with advanced urothelial cancer
Externí odkaz:
https://doaj.org/article/a82e3f41ebdc4c3989d1f4211495a2b2
Autor:
Aurora Laborda-Illanes, Lidia Sánchez-Alcoholado, Daniel Castellano-Castillo, Soukaina Boutriq, Isaac Plaza-Andrades, Lucía Aranega-Martín, Jesús Peralta-Linero, Emilio Alba, Alicia González-González, María Isabel Queipo-Ortuño
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 157, Iss , Pp 114041- (2023)
Melatonin is a molecule with different antitumor actions in breast cancer and has been described as an inhibitor of vascular endothelial growth factor (VEGF). Despite the recognition of the key role exerted by VEGF in tumor angiogenesis, limitations
Externí odkaz:
https://doaj.org/article/9ec277ca0d724e5bbd14f713ad064c34