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pro vyhledávání: '"Daniel, Burch"'
Autor:
Roberto Gomeni, Steven D. Targum, Mahnaz Asgharnejad, Timothy Petersen, Maurizio Fava, Daniel Burch
Publikováno v:
European Neuropsychopharmacology. 24:1188-1195
Band-pass filtering is a novel statistical methodology that proposes that filtering out data from trial sites generating non-plausible high or low levels of placebo response can yield a more accurate effect size and greater separation of active drug
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6bf02ef8954287ed5fdf2e416245e06
https://doi.org/10.1016/j.euroneuro.2014.06.003
https://doi.org/10.1016/j.euroneuro.2014.06.003
Publikováno v:
Clinical Pharmacology in Drug Development. 3:4-12
This Phase 1, single-center, double-blind, placebo-controlled, three-period study assessed cardiovascular safety of CX157, a specific Reversible Inhibitor of Monoamine Oxidase A (RIMA), following the oral administration of tyramine. In Period 1, the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3bd8b8e415838d040dd947bedb2e08ef
https://doi.org/10.1002/cpdd.61
https://doi.org/10.1002/cpdd.61
Autor:
Earle Bain, Thomas M. Shiovitz, Thomas P. Laughren, Daniel Burch, Phil Skolnick, Adam Hanina, David J. McCann
Publikováno v:
Journal of Clinical Pharmacology
Accounting for subject nonadherence and eliminating inappropriate subjects in clinical trials are critical elements of a successful study. Nonadherence can increase variance, lower study power, and reduce the magnitude of treatment effects. Inappropr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c784006bd8ae6476b11e338b1900f68f
https://pubmed.ncbi.nlm.nih.gov/26634893
https://pubmed.ncbi.nlm.nih.gov/26634893
Publikováno v:
Clinical pharmacology in drug development. 3(1)
This Phase 1, single-center, double-blind, placebo-controlled, three-period study assessed cardiovascular safety of CX157, a specific Reversible Inhibitor of Monoamine Oxidase A (RIMA), following the oral administration of tyramine. In Period 1, the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::04e16d7701840af379aaf1392bd641b2
https://pubmed.ncbi.nlm.nih.gov/27128224
https://pubmed.ncbi.nlm.nih.gov/27128224
Autor:
Millard Jayne, Payton King, Elena Shumay, Barry Scott Brand, Daniel Burch, Wei Zhu, Karen Apelskog-Torres, Scott Carter, Robert M. Fielding, Youwen Xu, Michael J. Schueller, David Alexoff, Gene-Jack Wang, Colleen Shea, James Cecil Free, Amy K Poshusta, Pauline Carter, Joanna S. Fowler, Barbara Hubbard, Frank Telang, Jean Logan, Donald Warner, Mahnaz Asgharnejad, Lisa Muench, Albert J. Azzaro
Publikováno v:
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. 35(3)
Reversible inhibitors of monoamine oxidase-A (RIMA) inhibit the breakdown of three major neurotransmitters, serotonin, norepinephrine and dopamine, offering a multi-neurotransmitter strategy for the treatment of depression. CX157 (3-fluoro-7-(2,2,2-t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::402e102d2b98772defd0d28f7ebd41a7
https://pubmed.ncbi.nlm.nih.gov/19890267
https://pubmed.ncbi.nlm.nih.gov/19890267
Publikováno v:
European Neuropsychopharmacology. (11):1760-1766
Signal detection requires ratings reliability throughout a clinical trial. The confirmation of site-based rater scores by a second, independent and blinded rater is a reasonable metric of ratings reliability. We used audio-digital pens to record site
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa05d2363713ddabe824d3bfcd8a9c2b
Autor:
Fiddler, Daniel Burch
Publikováno v:
Town Square; 2007 Collector's Issue, Vol. 1, p49-49, 1/2p
Conference
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