Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Danica, Mihalova"'
A new insight into effects of a clinically proved combination of methotrexate and hydroxychloroquine
Autor:
Lukas Slovak, Katarína Bauerová, Silvester Ponist, Radomír Nosáľ, Ľudmila Pašková, Viera Kuncirova, Viera Jančinová, Danica Mihalova
Publikováno v:
Monatshefte für Chemie - Chemical Monthly. 149:961-967
Combination of methotrexate (MTX) with hydroxychloroquine (HCQ) is one of the most effective therapies used for treatment of rheumatoid arthritis. The aim of the study was to more complexly examine the effect of combination HCQ and MTX on disease pro
Publikováno v:
European Pharmaceutical Journal, Vol 63, Iss 1, Pp 16-19 (2016)
The neuroprotective or neurotoxic effects of the products of the kynurenine pathway of tryptophan metabolism highly depend on the action of kynurenine-3-monooxygenase (KMO). The present results show increased concentrations of the KMO in the plasma o
Autor:
Silvester Ponist, O. Trunova, Tumová I, L. Rackova, T. Fedorova, Frantisek Drafi, Danica Mihalova, Viera Kuncirova, Lubos Danisovic, O. Ondrejickova, Katarína Bauerová
Publikováno v:
Oxidative Medicine and Cellular Longevity
Oxidative Medicine and Cellular Longevity, Vol 2016 (2016)
Oxidative Medicine and Cellular Longevity, Vol 2016 (2016)
Carnosine’s (CARN) anti-inflammatory potential in autoimmune diseases has been but scarcely investigated as yet. The aim of this study was to evaluate the therapeutic potential of CARN in rat adjuvant arthritis, in the model of carrageenan induced
Autor:
Radomír Nosáľ, Marianna Lucová, Katarína Drábiková, Tomáš Perečko, Danica Mihalova, Katarína Bauerová, Viera Jančinová, Silvia Pažoureková
Publikováno v:
International Immunopharmacology. 28:175-181
Hydroxychloroquine is used in the therapy of rheumatoid arthritis or lupus erythematosus. Although these diseases are often accompanied by activation of neutrophils, there are still few data relating to the impact of hydroxychloroquine on these cells
Autor:
Pauliková I, Danica Mihalova, Iveta Hrádková, Viera Kuncirova, Ľudmila Pašková, Radomír Nosáľ, Tomáš Čavojský, Juraj Harmatha, Lýdia Bezáková, František Bilka, Katarína Šišková, Silvester Ponist, Katarína Bauerová
Publikováno v:
Journal of Immunology Research
Journal of Immunology Research, Vol 2016 (2016)
Journal of Immunology Research, Vol 2016 (2016)
Rheumatoid arthritis (RA) is a chronic inflammatory disease, leading to progressive destruction of joints and extra-articular tissues, including organs such as liver and spleen. The purpose of this study was to compare the effects of a potential immu
Autor:
Frantisek Drafi, Silvester Ponist, Danica Mihalova, Radomír Nosál, T. Fedorova, Juraj Harmatha, Katarína Bauerová, Viera Kuncirova
Publikováno v:
Interdisciplinary Toxicology
Oxygen metabolism has an important role in the pathogenesis of rheumatoid arthritis. A certain correlation was observed between oxidative stress, arthritis and the immune system. Reactive oxygen species produced in the course of cellular oxidative ph
Autor:
Pavel Babal, Pavol Janega, Silvester Ponist, Danica Mihalova, Andrea Janegova, Katarína Bauerová, Lucia Feketeova, Petra Moravcová, Petra Jančová
Publikováno v:
Rheumatology International. 32:3517-3523
The aim of this study was to evaluate the morphological changes in the spleen, the thymus and the knee joints of rats with experimental adjuvant arthritis induced by Mycobacterium butyricum in the incomplete Freund's adjuvant and the effect of treatm
Autor:
Nicola Volpi, Danica Mihalova, Silvester Ponist, Viera Kuncirova, Katarína Bauerová, Ema Paulovičová
Publikováno v:
Osteoarthritis and Cartilage. 19(11):1373-1379
Summary Objective Rodent models of osteoarthritis and rheumatoid arthritis are useful tools to study these disease processes. Adjuvant arthritis (AAR) is a model of polyarthritis widely used for preclinical testing of antiarthritis substances. We rep
Autor:
Viera Jančinová, Katarína Drábiková, Katarína Bauerová, Radomír Nosáľ, Tomáš Perečko, Danica Mihalova
Publikováno v:
Interdisciplinary Toxicology. 4:11-14
Pharmacological regulation of neutrophil activity and apoptosis Novel strategies of antiinflammatory therapy are based upon pharmacological agents capable to enhance the resolution - i.e. the termination of the beneficial inflammation before it may t
Autor:
Grigorij Kogan, Silvester Ponist, Katarína Bauerová, Danica Mihalova, Radomír Nosáľ, Katarína Drábiková, Tomáš Perečko, Viera Jančinová
Publikováno v:
Pharmacological Research. 59:399-403
The effect of glucomannan (GM), a natural polysaccharide isolated from the yeast Candida utilis, on reactive oxygen species (ROS) generation in human neutrophils in vitro and in rats with Mycobacterium butyricum induced adjuvant arthritis (AA) was te