Zobrazeno 1 - 10
of 110
pro vyhledávání: '"Danian Chen"'
Publikováno v:
Chinese Medical Journal, Vol 137, Iss 9, Pp 1054-1068 (2024)
Abstract. Background:. Alterations in macular thickness and vascular density before clinically visible diabetic retinopathy (DR) remain inconclusive. This study aimed to determine whether retinal manifestations in abnormal glucose metabolism (AGM) pa
Externí odkaz:
https://doaj.org/article/0f50b18ac4b64bc295f4862968b80174
Autor:
Yu Lin, Wenyu Du, Xiangyu Fu, Ling Huang, Yiwen Hong, Haishan Tan, Lirong Xiao, Xiang Ren, Yujiao Wang, Danian Chen
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
Introduction: Chemicals, such as MNU (N-methyl-N-nitrosourea) and NaIO3 (sodium iodate), are widely used to induce retinal degeneration in rodents. Streptozotocin (STZ) is an analog of N-acetyl glucosamine in which an MNU moiety is linked to a hexose
Externí odkaz:
https://doaj.org/article/f9c6884e64cf48288dd933115734183a
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 14 (2024)
AimsThis study is designed to generalize and depict the research hotspots of endophthalmitis through bibliometric methods and software and analyze the evolutive tendency of the work on this severe disease over the past 30 years.MethodsThis study empl
Externí odkaz:
https://doaj.org/article/673f5b62ec85446582ca629c261c0a50
Autor:
Jing Su, Kaiqin She, Li Song, Xiu Jin, Ruiting Li, Qinyu Zhao, Jianlu Xiao, Danian Chen, Hui Cheng, Fang Lu, Yuquan Wei, Yang Yang
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 31, Iss , Pp 596-609 (2023)
Retinitis pigmentosa (RP) is a group of retinal diseases that cause the progressive death of retinal photoreceptor cells and eventually blindness. Mutations in the β-domain of the phosphodiesterase 6 (Pde6b) gene are the most identified causes of au
Externí odkaz:
https://doaj.org/article/5ec30796bfbe45b8936cdf509809cbdf
Publikováno v:
Heliyon, Vol 9, Iss 10, Pp e21109- (2023)
Background: Diabetic retinopathy (DR) is a common complication in diabetic patients. DR is also a neurodegenerative disease. Patients with hyperglycemia, hyperlipidemia, and hypertension are vulnerable to retinopathy development. While the roles of b
Externí odkaz:
https://doaj.org/article/1542491ec6be4bc6852c9bb9a7baa05c
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 13 (2023)
IntroductionRecently the role of gut microbial dysbiosis in many ocular disorders, including but not limited to uveitis, age-related macular degeneration (AMD), diabetic retinopathy (DR), dry eye, keratitis and orbitopathy is a hot research topic in
Externí odkaz:
https://doaj.org/article/adc8aa6f90fe4de6b58ec9e49adf5bd4
Autor:
Yimeng Fan, Wenyue Chen, Ran Wei, Wei Qiang, Joel D. Pearson, Tao Yu, Rod Bremner, Danian Chen
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-11 (2022)
The Pax6-α-Cre mouse line used in retinal studies actually contains four transgene insertion within gene clusters of olfactory and vomeronasal receptors, leading to expression in not just retinal, but also olfactory and vomeronasal sensory neurons.
Externí odkaz:
https://doaj.org/article/f321428e28b24f4799fff4221b78fcda
Publikováno v:
Frontiers in Neuroanatomy, Vol 16 (2022)
Glaucoma is a leading cause of blindness with progressive degeneration of retinal ganglion cells. Aging and increased intraocular pressure (IOP) are major risk factors. Lowering IOP does not always stop the disease progression. Alternative ways of pr
Externí odkaz:
https://doaj.org/article/9dc6c1e55ce844ff9ee678cc5a333fa7
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Atherosclerosis (AS) is a pathological process involving lipid oxidation, immune system activation, and endothelial dysfunction. The activated immune system could lead to inflammation and oxidative stress. Risk factors like aging and hyperhomocystein
Externí odkaz:
https://doaj.org/article/afe36e71075345fdb513f7ac973f2493
Publikováno v:
Frontiers in Genetics, Vol 13 (2022)
Baraitser–Winter cerebrofrontofacial syndrome (BWCFF, OMIM: 243310) is a rare autosomal-dominant developmental disorder associated with variants in the genes ACTB or ACTG1. It is characterized by brain malformations, a distinctive facial appearance
Externí odkaz:
https://doaj.org/article/c6a39a4462f64719affe034049136e7d