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A Single-Strand Helical Motif Induced by Self-Assembly of [Ag(TFP)]+ Moieties with Nitrate Anions −31P NMR Spectroscopic and X-ray Crystal Structure Characterization of the Complexes Involved in Equilibrium Reactions of Silver Salts and TFP Ligand

Autor: Rossana Galassi, Dania Tesei, Alfredo Burini, Fiorella Bachechi, Bianca Rosa Pietroni

Publikováno v: European Journal of Inorganic Chemistry. 2002:2086-2093

The ability of the ligand tris(2-furyl)phosphane (TFP) to coordinate AgI ions has been investigated. The molar ratio and the nature of the counterions used (NO3−; BF4−) affected the reaction. Moreover, equilibrium reactions were observed and the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba95448d581a01e547bac97bb3f0e400
https://doi.org/10.1002/1099-0682(200208)2002:8<2086::aid-ejic2086>3.0.co

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4,5-Dihydro-1H-pyrazolo[4,3-h]quinazolines as potent and selective Polo-like kinase 1 (PLK1) inhibitors

Autor: Michele Caruso, Francesco Fiorentini, Francesco Sola, Maria Laura Giorgini, Laura Gianellini, Italo Beria, Fulvia Roletto, Maria Gabriella Brasca, Maristella Colombo, Barbara Valsasina, Ron Ferguson, Gabriele Fachin, Dania Tesei, Helena Posteri, Jurgen Moll, Walter Ceccarelli, Daniele Pezzetta, Sabrina Cribioli

Publikováno v: Bioorganicmedicinal chemistry letters. 20(22)

A series of 4,5-dihydro-1H-pyrazolo[4,3-h]quinazoline derivatives was optimized as Polo-like kinase 1 inhibitors. Extensive SAR afforded a highly potent and selective PLK1 compound. The compound showed good antiproliferative activity when tested in a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93859b798e1a9fac70cabff937780dcf
https://pubmed.ncbi.nlm.nih.gov/20932759

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