Výsledky vyhledávání

Akademický článek

Extracellular vesicles in non-small cell lung cancer stemness and clinical applications

Autor: Prita Pandya, Dania S. Al-Qasrawi, Skyeler Klinge, Verline Justilien

Publikováno v: Frontiers in Immunology, Vol 15 (2024)

Non-small cell lung carcinoma (NSCLC) accounts for 85% of lung cancers, the leading cause of cancer associated deaths in the US and worldwide. Within NSCLC tumors, there is a subpopulation of cancer cells termed cancer stem cells (CSCs) which exhibit

Externí odkaz: https://doaj.org/article/50033c8eb97c4e79b3efcabc6cb08369

Zobrazit plný text záznamu

Akademický článek

Development of canagliflozin nanocrystals sublingual tablets in the presence of sodium caprate permeability enhancer: formulation optimization, characterization, in-vitro, in silico, and in-vivo study

Autor: Sammar Fathy Elhabal, Mohamed A El-Nabarawi, Nashwa Abdelaal, Mohamed Fathi Mohamed Elrefai, Shrouk A. Ghaffar, Mohamed Mansour Khalifa, Passant M. Mohie, Dania S. Waggas, Ahmed Mohsen Elsaid Hamdan, Samar Zuhair Alshawwa, Essa M. Saied, Nahla A. Elzohairy, Tayseer Elnawawy, Rania A. Gad, Nehal Elfar, Hanaa Mohammed, Mohammad Ahmad Khasawneh

Publikováno v: Drug Delivery, Vol 30, Iss 1 (2023)

AbstractCanagliflozin (CFZ) is a sodium-glucose cotransporter-2 inhibitor (SGLT2) that lowers albuminuria in type-2 diabetic patients, cardiovascular, kidney, and liver disease. CFZ is classified as class IV in the Biopharmaceutical Classification Sy

Externí odkaz: https://doaj.org/article/a2cf42c96704498086c5780200e30e93

Zobrazit plný text záznamu

Plný text ve formátu HTML

Akademický článek

The Protective and Therapeutic Anti-Alzheimer Potential of Olea europaea L. cv. Picual: An In Silico and In Vivo Study

Autor: Alaa A. Bagalagel, Seham S. El-hawary, Rania Alaaeldin, Abeer H. Elmaidomy, Faisal H. Altemani, Dania S. Waggas, Naseh A. Algehainy, Nizar H. Saeedi, Faisal Alsenani, Fatma A. Mokhtar, Mahmoud A. Elrehany, Mohammad M. Al-Sanea, Usama Ramadan Abdelmohsen

Publikováno v: Metabolites, Vol 12, Iss 12, p 1178 (2022)

LC-HRESIMS metabolomic profiling of Olea europaea L. cv. Picual (OEP) (Saudi Arabian olive cultivar, F. Oleacea) revealed 18 compounds. Using pharmacology networking to specify the targets of the identified compounds with a relationship to Alzheimer�

Externí odkaz: https://doaj.org/article/0e406cdfaa2442d1ade0537ddefae8b5

Zobrazit plný text záznamu

Akademický článek

Parkinson's Disease in Saudi Patients: A Genetic Study.

Autor: Bashayer R Al-Mubarak, Saeed A Bohlega, Thamer S Alkhairallah, Amna I Magrashi, Maha I AlTurki, Dania S Khalil, Basma S AlAbdulaziz, Hussam Abou Al-Shaar, Abeer E Mustafa, Eman A Alyemni, Bashayer A Alsaffar, Asma I Tahir, Nada A Al Tassan

Publikováno v: PLoS ONE, Vol 10, Iss 8, p e0135950 (2015)

Parkinson's disease (PD) is one of the major causes of parkinsonism syndrome. Its characteristic motor symptoms are attributable to dopaminergic neurons loss in the midbrain. Genetic advances have highlighted underlying molecular mechanisms and provi

Externí odkaz: https://doaj.org/article/f62aea7f0947470ea1bff78fbff8926b

Zobrazit plný text záznamu