Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Dania Al-Sharify"'
Autor:
Pratibha Singh, Jiangming Sun, Michele Cavalera, Dania Al-Sharify, Frank Matthes, Mohammad Barghouth, Christoffer Tengryd, Pontus Dunér, Ana Persson, Lena Sundius, Mihaela Nitulescu, Eva Bengtsson, Sara Rattik, Daniel Engelbertsen, Marju Orho-Melander, Jan Nilsson, Claudia Monaco, Isabel Goncalves, Andreas Edsfeldt
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-18 (2024)
Abstract Type 2 diabetes is associated with cardiovascular disease, possibly due to impaired vascular fibrous repair. Yet, the mechanisms are elusive. Here, we investigate alterations in the fibrous repair processes in type 2 diabetes atherosclerotic
Externí odkaz:
https://doaj.org/article/41f3f64314b845278c7dabbc504aabd2
Autor:
Dania Al-Sharify, Signe Holm Nielsen, Frank Matthes, Christoffer Tengryd, Jiangming Sun, Federica Genovese, Morten A. Karsdal, Jan Nilsson, Isabel Goncalves, Andreas Edsfeldt
Publikováno v:
Al-Sharify, D, Nielsen, S H, Matthes, F, Tengryd, C, Sun, J, Genovese, F, Karsdal, M A, Nilsson, J, Goncalves, I & Edsfeldt, A 2022, ' Increased proteolytic cleavage of osteoglycin is associated with a stable plaque phenotype and lower risk of cardiovascular events ', Atherosclerosis, vol. 355, pp. 8-14 . https://doi.org/10.1016/j.atherosclerosis.2022.06.1025
Background and aimsExtracellular matrix (ECM) remodeling is one of the key components in the formation of vulnerable atherosclerotic plaques and cardiovascular events. We recently showed that the full-length ECM-proteoglycan osteoglycin was associate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d51d72f1214d4130fd17bbc85fd80647
https://pubmed.ncbi.nlm.nih.gov/35850021
https://pubmed.ncbi.nlm.nih.gov/35850021
Autor:
Andreas Edsfeldt, Maarten Swart, Pratibha Singh, Lea Dib, Jiangming Sun, Jennifer E Cole, Inhye Park, Dania Al-Sharify, Ana Persson, Mihaela Nitulescu, Patricia Das Neves Borges, Christina Kassiteridi, Michael E Goddard, Regent Lee, Petr Volkov, Marju Orho-Melander, Lars Maegdefessel, Jan Nilsson, Irina Udalova, Isabel Goncalves, Claudia Monaco
Publikováno v:
European heart journal. 43(19)
Aims: Inflammation is a key factor in atherosclerosis. The transcription factor interferon regulatory factor-5 (IRF5) drives macrophages towards a pro-inflammatory state. We investigated the role of IRF5 in human atherosclerosis and plaque stability.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca9bd50fc6622a4a9c4b0e3914511ce4
https://pubmed.ncbi.nlm.nih.gov/35567557
https://pubmed.ncbi.nlm.nih.gov/35567557