Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Dania, Hussein"'
Autor:
Manar Alghamdi, Sarah Almustafa, Hadi Alsaihaty, Mohammed Gomaa, AlAnood Alhowsawi, Dania Hussein, Abdullah Almatrafi
Publikováno v:
F1000Research, Vol 12 (2024)
Background: The protein interaction between the viral surface S-glycoprotein and the host angiotensin converting enzyme-2 receptor (ACE2) is key to the virulent nature of SARS-CoV-2. The potential role that effective drug repurposing strategies may h
Externí odkaz:
https://doaj.org/article/1cc6a0f367644df3ba45f740727de8b0
Autor:
Mohamed Gomaa, Wael Gad, Dania Hussein, Faheem Hyder Pottoo, Nada Tawfeeq, Mansour Alturki, Dhay Alfahad, Razan Alanazi, Ismail Salama, Mostafa Aziz, Aboelnasr Zahra, Abeer Hanafy
Publikováno v:
Pharmaceuticals, Vol 17, Iss 2, p 189 (2024)
Drug repurposing is a promising approach that has the potential to revolutionize the drug discovery and development process. By leveraging existing drugs, we can bring new treatments to patients more quickly and affordably. Anti-inflammatory drugs ha
Externí odkaz:
https://doaj.org/article/6d96fd8d3aaa4ea58b0520cc11483997
Autor:
Alaa Alahmadi, Aisha Alansari, Nawal Alsheikh, Salam Alshammasi, Mona Alshamery, Rand Al-abdulmohsin, Laila Al Rabia, Fatimah Al Nass, Manar Alghamdi, Sarah Almustafa, Zainab Aljamea, Sawsan Kurdi, Md. Ashraful Islam, Dania Hussein
Publikováno v:
Informatics in Medicine Unlocked, Vol 42, Iss , Pp 101341- (2023)
The coronavirus disease 2019 (COVID-19) has overwhelmed healthcare systems and continues to pose a significant threat worldwide. Predicting disease severity would enhance treatment provision and resource allocation. Although multiple studies were con
Externí odkaz:
https://doaj.org/article/87acfe3236e1447899811cd848e6dff0
Physicochemical and biopharmaceutical characterization of new sulfonamide derivatives of gallic acid
Autor:
Dania Hussein Alhyari, Helen Sheldrake, Sriharsha Kantamneni, Mohammad Isreb, Shohreh Jafarinejad Soumehsaraei, William Martin, Nidal Qinna, Krzysztof Paluch
Publikováno v:
British Journal of Pharmacy, Vol 7, Iss 2 (2022)
Gallic acid (GA) is known for its antioxidant activity which is restricted due to its low oral permeability. In this project the carboxylic group of (GA) was substituted with sulfonamide group and hydroxyl groups were methylated which resulted insign
Externí odkaz:
https://doaj.org/article/b1457e6f88984cc0815597d14127fe8b
Autor:
Dania Hussein, Abdullah Rahail Almatrafi, Mohammed Sayed Mansour, Alanood Howsawi, Sarah Almustafa, Hadi Alsaihaty, Manar Alghamdi
Publikováno v:
SSRN Electronic Journal.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::84dc46f0321a50a18bba3d5abf4deaaf
https://doi.org/10.2139/ssrn.4110412
https://doi.org/10.2139/ssrn.4110412
Autor:
Lamia, Heikal, Anna, Starr, Dania, Hussein, Jesus, Prieto-Lloret, Phil, Aaronson, Lea Ann, Dailey, Manasi, Nandi
Publikováno v:
JACC. Basic to Translational Science
Visual Abstract
Highlights • Tetrahydrobiopterin is an essential cofactor for NO production. • Limitation of endogenous tetrahydrobiopterin reduces NO bioavailability, enhances oxidative stress, and impairs vascular function. • Orally supp
Highlights • Tetrahydrobiopterin is an essential cofactor for NO production. • Limitation of endogenous tetrahydrobiopterin reduces NO bioavailability, enhances oxidative stress, and impairs vascular function. • Orally supp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::166376ef4af2c73ef541c9bd95b774dd
https://pubmed.ncbi.nlm.nih.gov/29963647
https://pubmed.ncbi.nlm.nih.gov/29963647
Autor:
Alqurain, Aymen A.1 (AUTHOR) aymen.alqurain@nbu.edu.sa, Alomar, Mohammed F.2 (AUTHOR) 2190005716@iau.edu.sa, Fakhreddin, Shatha3 (AUTHOR) 2021201450@machs.edu.sa, Julayh, Zahrah3 (AUTHOR), Korikeesh, Zahra3 (AUTHOR), Al-Shaibi, Samaher3 (AUTHOR), Alshnbari, Afnan3 (AUTHOR), Al Helaili, Alaa4 (AUTHOR), Ameer, Luma3 (AUTHOR), Surour, Manal3 (AUTHOR), Ghosn, Sherihan3 (AUTHOR), Hussein, Dania5 (AUTHOR) dahussein@iau.edu.sa, AlAlwan, Bader6 (AUTHOR), Alomar, Fadhel A.5 (AUTHOR) aymen.alqurain@nbu.edu.sa, Bidasee, Keshore R.7,8 (AUTHOR) aymen.alqurain@nbu.edu.sa
Publikováno v:
Journal of Clinical Medicine. Oct2024, Vol. 13 Issue 20, p6187. 16p.
Publikováno v:
Starr, A, Hussein, D & Nandi, M 2013, ' The regulation of vascular tetrahydrobiopterin bioavailability ', VASCULAR PHARMACOLOGY, vol. 58, no. 3, pp. 219-230 . https://doi.org/10.1016/j.vph.2012.08.002
6R l-erythro-5,6,7,8-tetrahydrobiopterin (BH4) is an essential cofactor for several enzymes including phenylalanine hydroxylase and the nitric oxide synthases (NOS). Oral supplementation of BH4 has been successfully employed to treat subsets of patie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db2efefff481cf05cd434ac7b1cc41df
https://pubmed.ncbi.nlm.nih.gov/23634439
https://pubmed.ncbi.nlm.nih.gov/23634439
Publikováno v:
Nitric Oxide. 27:S29-S30
Tetrahydrobiopterin (BH4) is an essential cofactor for aromatic amino acid-hydroxylases and all isoforms of nitric oxide-synthase. In the cardiovascular system nitric oxide (NO) elicits potent vasodilatory and antithrombotic effects and maintains end
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2b39eb0821290dace9e9704ee77a980e
https://doi.org/10.1016/j.niox.2012.04.105
https://doi.org/10.1016/j.niox.2012.04.105
Publikováno v:
Vascular Pharmacology. 56:353
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::574f2460ceef3b157e81fd580429a3c3
https://doi.org/10.1016/j.vph.2011.08.131
https://doi.org/10.1016/j.vph.2011.08.131