Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Dani R. Smith"'
Autor:
Shanu eGeorge, Shilpa D Kadam, Natasha D Irving, Geoffrey J Markowitz, Saba eRaja, Anthony eKwan, YuShan eTu, Huigen eChen, Charles eRohde, Dani R Smith, Anne Marie Comi
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 7 (2013)
Stroke in the neonatal brain frequently results in neurologic impairments including cognitive disability. We investigated the effect of long-term sodium valproate (valproate) and Trichostatin A (TSA) treatment upon post-stroke neurogenesis in the den
Externí odkaz:
https://doaj.org/article/8df1139f9ac7444f924de97ff6c76455
Publikováno v:
Schizophrenia Research. 171:187-194
The hippocampus of patients with schizophrenia displays aberrant excess neuronal activity which affects cognitive function. Animal models of the illness have recapitulated the overactivity in the hippocampus, with a corresponding regionally localized
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03735be8437d56df4289e308227062b0
https://doi.org/10.1016/j.schres.2016.01.023
https://doi.org/10.1016/j.schres.2016.01.023
Autor:
Gloria E. Hoffman, Yew Ei Tan, Michael V. Johnston, Dani R. Smith, Karen S. Smith-Connor, Mary E. Blue, Amanda Fowler, Charlotte Eyring, Sujatha Kannan, Elizabeth S. Smith, Maria Braileanu
Publikováno v:
Neurobiol Learn Mem
Rett Syndrome (RTT) is a genetic disorder that is caused by mutations in the x-linked gene coding for methyl-CpG-biding-protein 2 (MECP2) and that mainly affects females. Male and female transgenic mouse models of RTT have been studied extensively, a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::887b0d3e1b0c751b0ace4018af1cc1df
https://europepmc.org/articles/PMC8040058/
https://europepmc.org/articles/PMC8040058/
Autor:
Ishrat Ahmed, Maged M. Harraz, Risheng Xu, Daniel J. Blech, Dani R. Smith, Michela Gallagher, Feng Rao, Prasun Guha, M. Scott Vandiver, Solomon H. Snyder, Nilkantha Sen, Bindu D. Paul, A. Basit Khan, Richa Tyagi
Publikováno v:
Proceedings of the National Academy of Sciences. 110:16181-16186
Profound induction of immediate early genes (IEGs) by neural activation is a critical determinant for plasticity in the brain, but intervening molecular signals are not well characterized. We demonstrate that inositol polyphosphate multikinase (IPMK)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c6346c4d6337db0521f8c6308990eca
https://doi.org/10.1073/pnas.1315551110
https://doi.org/10.1073/pnas.1315551110
Publikováno v:
Neuroscience research. 107
Recent clinical studies have suggested a role for immune/inflammatory responses in the pathophysiology of psychosis. However, a mechanistic understanding of this process and its application for drug discovery is underdeveloped. Here we assessed our r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55f8f2b09efdcdcd3639480b4424b02e
https://pubmed.ncbi.nlm.nih.gov/26869217
https://pubmed.ncbi.nlm.nih.gov/26869217
Publikováno v:
Epilepsy Research. 94:138-148
Summary Neonatal stroke presents with seizures that are usually treated with phenobarbital. We hypothesized that anticonvulsants would attenuate ischemic injury, but that the dose-dependent effects of standard anticonvulsants would impact important a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5080ee02fd59b25906659224d052bae6
https://doi.org/10.1016/j.eplepsyres.2011.01.002
https://doi.org/10.1016/j.eplepsyres.2011.01.002
Autor:
Dani R. Smith, Jung-Soo Han, Michela Gallagher, Jae Chun Song, Jeiwon Cho, Seol Heui Han, Yoo Kyeong Hwang
Publikováno v:
Brain Research. 1345:156-163
The effects of genetic background on fear trace conditioning were evaluated in relation to phosphorylated levels of cAMP response element-binding protein (CREB) in the hippocampus using two different inbred strains of mice, C57BL/6 and DBA/2. The mal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f901664e1cf26ad4d43ba20f056aebdf
https://doi.org/10.1016/j.brainres.2010.05.048
https://doi.org/10.1016/j.brainres.2010.05.048
Publikováno v:
Learning & Memory. 14:597-605
Fear conditioning, including variants such as delay and trace conditioning that depend on different neural systems, is widely used to behaviorally characterize genetically altered mice. We present data from three strains of mice, C57/BL6 (C57), 129/S
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a485418bb2ae000f320a8ad96b3da22
https://doi.org/10.1101/lm.614807
https://doi.org/10.1101/lm.614807
Autor:
Eileen C. Hoyt, Jennifer L. Bizon, Kassie Helm, Michela Gallagher, Rebecca P. Haberman, Dani R. Smith, P. Kay Lund
Publikováno v:
Experimental Gerontology. 39:1613-1622
Aging related cognitive decline is an increasing health problem but affects only a subset of elderly humans. This research uses outbred young (Y) and aged rats. Behavioral characterization distinguishes aged rats with impaired spatial learning (AI) a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc041a4d9cac57344807a4e28bbc57d9
https://doi.org/10.1016/j.exger.2004.06.018
https://doi.org/10.1016/j.exger.2004.06.018
Autor:
Ashley M. Blouin, Jong Ah J. Lee, Alexander W. Johnson, Jay M. Baraban, Dani R. Smith, Irving M. Reti, Bo Tao
Publikováno v:
Behavioural brain research. 257
Narp knockout (KO) mice demonstrate cognitive inflexibility and addictive behavior, which are associated with abnormal reactivity to a novel stimulus. To assess reactivity to novelty, we tested Narp KO and wild-type (WT) mice on a neophobia procedure
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e1bf7ffd7a3a3b055999da920c7c548e
https://pubmed.ncbi.nlm.nih.gov/24120400
https://pubmed.ncbi.nlm.nih.gov/24120400