Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Daniëlle van Manen"'
Autor:
Lucy Rutten, Maarten Swart, Annemart Koornneef, Pascale Bouchier, Sven Blokland, Ava Sadi, Jarek Juraszek, Aneesh Vijayan, Sonja Schmit-Tillemans, Johan Verspuij, Ying Choi, Chenandly E. Daal, Aditya Perkasa, Shessy Torres Morales, Sebenzile K. Myeni, Marjolein Kikkert, Jeroen Tolboom, Daniëlle van Manen, Harmjan Kuipers, Hanneke Schuitemaker, Roland Zahn, Johannes P. M. Langedijk
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-10 (2024)
Abstract The spike protein (S) of SARS-CoV-2 induces neutralizing antibodies and is the key component of current COVID-19 vaccines. The most efficacious COVID-19 vaccines are genetically-encoded spikes with a double proline substitution in the hinge
Externí odkaz:
https://doaj.org/article/2c5d3e1e3a7e47e1962a95fc294bb57c
Autor:
Jean-Louis Spadoni, Pierre Rucart, Sigrid Le Clerc, Daniëlle van Manen, Cédric Coulonges, Damien Ulveling, Vincent Laville, Taoufik Labib, Lieng Taing, Olivier Delaneau, Matthieu Montes, Hanneke Schuitemaker, Josselin Noirel, Jean-François Zagury
Publikováno v:
PLoS ONE, Vol 10, Iss 9, p e0136989 (2015)
Many genome-wide association studies have been performed on progression towards the acquired immune deficiency syndrome (AIDS) and they mainly identified associations within the HLA loci. In this study, we demonstrate that the integration of biologic
Externí odkaz:
https://doaj.org/article/e47dcb57fdbe44a393f45f5c810623a0
Autor:
Martijn Schenning, Claudia M. van Tiel, Daniëlle van Manen, Jord C. Stam, Barend M. Gadella, Karel W.A. Wirtz, Gerry T. Snoek
Publikováno v:
Journal of Lipid Research, Vol 45, Iss 8, Pp 1555-1564 (2004)
Mouse fibroblast cells overexpressing phosphatidylinositol transfer protein α [PI-TPα; sense PI-TPα (SPIα) cells] show a significantly increased rate of proliferation and an extreme resistance toward ultraviolet- or tumor necrosis factor-α-induc
Externí odkaz:
https://doaj.org/article/7b6a912c48804825be7ccd62a72321a4
Autor:
Zelda Euler, Marit J van Gils, Brigitte D Boeser-Nunnink, Hanneke Schuitemaker, Daniëlle van Manen
Publikováno v:
PLoS ONE, Vol 8, Iss 1, p e54684 (2013)
Broadly neutralizing antibodies may protect against HIV-1 acquisition. In natural infection, only 10-30% of patients have cross-reactive neutralizing humoral immunity which may relate to viral and or host factors. To explore the role of host genetic
Externí odkaz:
https://doaj.org/article/753aa99c8e554599a240346872978861
Autor:
Paul J McLaren, Cédric Coulonges, Stephan Ripke, Leonard van den Berg, Susan Buchbinder, Mary Carrington, Andrea Cossarizza, Judith Dalmau, Steven G Deeks, Olivier Delaneau, Andrea De Luca, James J Goedert, David Haas, Joshua T Herbeck, Sekar Kathiresan, Gregory D Kirk, Olivier Lambotte, Ma Luo, Simon Mallal, Daniëlle van Manen, Javier Martinez-Picado, Laurence Meyer, José M Miro, James I Mullins, Niels Obel, Stephen J O'Brien, Florencia Pereyra, Francis A Plummer, Guido Poli, Ying Qi, Pierre Rucart, Manj S Sandhu, Patrick R Shea, Hanneke Schuitemaker, Ioannis Theodorou, Fredrik Vannberg, Jan Veldink, Bruce D Walker, Amy Weintrob, Cheryl A Winkler, Steven Wolinsky, Amalio Telenti, David B Goldstein, Paul I W de Bakker, Jean-François Zagury, Jacques Fellay
Publikováno v:
PLoS Pathogens, Vol 9, Iss 7, p e1003515 (2013)
Multiple genome-wide association studies (GWAS) have been performed in HIV-1 infected individuals, identifying common genetic influences on viral control and disease course. Similarly, common genetic correlates of acquisition of HIV-1 after exposure
Externí odkaz:
https://doaj.org/article/8b487ebc53ca4a4eae671f4a5970e634
Autor:
Sebastiaan M Bol, Thijs Booiman, Daniëlle van Manen, Evelien M Bunnik, Ard I van Sighem, Margit Sieberer, Brigitte Boeser-Nunnink, Frank de Wolf, Hanneke Schuitemaker, Peter Portegies, Neeltje A Kootstra, Angélique B van 't Wout
Publikováno v:
PLoS ONE, Vol 7, Iss 2, p e30990 (2012)
BACKGROUND: Infection with HIV-1 may result in severe cognitive and motor impairment, referred to as HIV-1-associated dementia (HAD). While its prevalence has dropped significantly in the era of combination antiretroviral therapy, milder neurocogniti
Externí odkaz:
https://doaj.org/article/39162ba0da244103989f1c69d89be247
Autor:
Sebastiaan M Bol, Perry D Moerland, Sophie Limou, Yvonne van Remmerden, Cédric Coulonges, Daniëlle van Manen, Joshua T Herbeck, Jacques Fellay, Margit Sieberer, Jantine G Sietzema, Ruben van 't Slot, Jeremy Martinson, Jean-François Zagury, Hanneke Schuitemaker, Angélique B van 't Wout
Publikováno v:
PLoS ONE, Vol 6, Iss 2, p e17190 (2011)
HIV-1 infected macrophages play an important role in rendering resting T cells permissive for infection, in spreading HIV-1 to T cells, and in the pathogenesis of AIDS dementia. During highly active anti-retroviral treatment (HAART), macrophages keep
Externí odkaz:
https://doaj.org/article/ec933f9d95a943fd86decd23dded18ac
Autor:
Daniëlle van Manen, Olivier Delaneau, Neeltje A Kootstra, Brigitte D Boeser-Nunnink, Sophie Limou, Sebastiaan M Bol, Judith A Burger, Aeilko H Zwinderman, Perry D Moerland, Ruben van 't Slot, Jean-François Zagury, Angélique B van 't Wout, Hanneke Schuitemaker
Publikováno v:
PLoS ONE, Vol 6, Iss 7, p e22208 (2011)
BACKGROUND: AIDS develops typically after 7-11 years of untreated HIV-1 infection, with extremes of very rapid disease progression (15 years). To reveal additional host genetic factors that may impact on the clinical course of HIV-1 infection, we des
Externí odkaz:
https://doaj.org/article/9eb3b24a55104c6095df7a7a21e54918
Autor:
Daniëlle van Manen, Maarten A N Rits, Corrine Beugeling, Karel van Dort, Hanneke Schuitemaker, Neeltje A Kootstra
Publikováno v:
PLoS Pathogens, Vol 4, Iss 2, p e18 (2008)
The antiviral factor tripartite interaction motif 5alpha (Trim5alpha) restricts a broad range of retroviruses in a species-specific manner. Although human Trim5alpha is unable to block HIV-1 infection in human cells, a modest inhibition of HIV-1 repl
Externí odkaz:
https://doaj.org/article/7b1a1eb83b8b45e39f23fa13e36a2a56
Autor:
Annemart Koornneef, Kanika Vanshylla, Gijs Hardenberg, Lucy Rutten, Nika M. Strokappe, Jeroen Tolboom, Jessica Vreugdenhil, Karin Feddes-de Boer, Aditya Perkasa, Sven Blokland, Judith A. Burger, Wei-Chiao Huang, Jonathan F. Lovell, Danielle van Manen, Rogier W. Sanders, Roland C. Zahn, Hanneke Schuitemaker, Johannes P. M. Langedijk, Frank Wegmann
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract One of the strategies towards an effective HIV-1 vaccine is to elicit broadly neutralizing antibody responses that target the high HIV-1 Env diversity. Here, we present an HIV-1 vaccine candidate that consists of cobalt porphyrin-phospholipi
Externí odkaz:
https://doaj.org/article/b47f9ae471c641c184638edf81cb1133