Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Daniël Broekaert"'
Publikováno v:
Vrije Universiteit Brussel
Leptin was originally identified as an adipocyte-derived cytokine with a key role in the regulation of the energy balance. Subsequent research has, however, revealed that leptin's biological action is not restricted to its effects on appetite and foo
Autor:
Sheng-Jiun Wu, Daniël Broekaert, Jan Tavernier, Iris Behrmann, Peter C. Heinrich, Lennart Zabeau, Joël Vandekerckhove, Annick Verhee, José Van der Heyden, Irwin Chaiken
Publikováno v:
European Journal of Immunology. 31:1087-1097
IL-5 is a major determinant in the survival, differentiation and effector-functions of eosinophils. It mediates its effect upon binding and activation of a membrane bound receptor (R), composed of a ligand-specific alpha-chain and a beta-chain, share
Identification of the Y985 and Y1077 motifs as SOCS3 recruitment sites in the murine leptin receptor
Publikováno v:
FEBS Letters. 486:33-37
The leptin system provides a link between adipose mass and the central nervous system. The appetite suppressing effects of leptin are impaired in most obese patients and some mutant mice strains. Herein we describe how suppressor of cytokine signalli
Autor:
Jan Tavernier, Annick Verhee, Sven Eyckerman, Joël Vandekerckhove, Daniël Broekaert, John H. Beattie, Wim Waelput
Publikováno v:
Vrije Universiteit Brussel
Using PC12 cells as an in vitro model system, we have identified a series of transcripts induced through activation of the leptin receptor. On the basis of kinetic studies, two distinct gene sets could be discerned: signal transducer and activator of
Publikováno v:
Research in Veterinary Science. 62:165-169
Ulceration of the gastric pars oesophagea is a serious problem in the pig industry, and in spite of numerous studies the underlying mechanisms of the development of such ulcers remains largely unknown. The present study was designed first to test the
Autor:
Daniël Broekaert, Tony Houthaeve, Kris Gevaert, Hans Demol, Joël Vandekerckhove, Magda Puype, Stefaan De Boeck
Publikováno v:
Electrophoresis. 18:2950-2960
We here describe a procedure for concentrating peptides from solutions by adsorbing them onto reverse-phase beads that were added to these solutions. The beads are then transferred to the target disc of the matrix assisted laser desorption ionization
Autor:
Daniël Broekaert, D Boedts
Publikováno v:
Acta Oto-Laryngologica. 113:345-348
Using monoclonal antibodies specific for CK chains and the indirect immunoperoxidase technique, the expression of 10 CK polypeptides was investigated. The external stratified squamous epithelium of the tympanic membrane generally expressed CKs 5, 10
Autor:
Frans C. S. Ramaekers, Goos N. P. van Muijen, P. Coucke, Irene M. Leigh, Daniël Broekaert, Dirk Boedts, Sabine Leperque, B. Lane
Publikováno v:
Annals of Otology, Rhinology & Laryngology. 101:931-938
Immunohistochemical investigations were carried out to determine the pattern of cytokeratin (CK) expression in middle ear cholesteatoma and related epithelia. Using monoclonal antibodies specific for CK chains and the indirect immunoperoxidase techni
Publikováno v:
Vrije Universiteit Brussel
Leptin was originally identified as an adipocyte-derived cytokine with a key role in the regulation of the energy balance. Subsequent research revealed that leptin's biological action is not restricted to its effects on appetite and food intake, but
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cbf11ade28363cffdf5fdd5ad0982d41
https://hdl.handle.net/20.500.14017/8a8ce4f3-08bf-481c-a86c-8cf3ce04b386
https://hdl.handle.net/20.500.14017/8a8ce4f3-08bf-481c-a86c-8cf3ce04b386
Autor:
Daniël, Broekaert, Sven, Eyckerman, Delphine, Lavens, Annick, Verhee, Wim, Waelput, Joël, Vandekerckhove, Jan, Tavernier
Publikováno v:
European cytokine network. 13(1)
The pancreatitis-associated protein (PAP)/regenerating protein (REG) family represents a complex group of small secretory proteins, which can function as acute phase reactants, lectins, antiapoptotic factors or growth factors for pancreatic beta-cell