Exclusive Postsynaptic Action of Hypocretin-Orexin on Sublayer 6b Cortical Neurons

Autor: Mauro Serafin, Laurence Bayer, Danièle Machard, Barbara E. Jones, Michel Muhlethaler, Emmanuel Eggermann, Benoît Saint-Mleux

Publikováno v: Journal of Neuroscience, Vol. 24, No 30 (2004) pp. 6760-6764

The hypocretin-orexin (hcrt-orx) neurons are thought to maintain wakefulness because their loss results in narcolepsy. This role may be fulfilled by the excitatory action that the hcrt-orx peptide exerts on multiple brainstem and forebrain systems th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3fba3d8358c3d1788614d6569c787a70
https://doi.org/10.1523/jneurosci.1783-04.2004

Orexins/hypocretins excite basal forebrain cholinergic neurones

Autor: Danièle Machard, Benoît Saint-Mleux, Laurence Bayer, Mauro Serafin, Emmanuel Eggermann, Michel Muhlethaler, Barbara E. Jones

Publikováno v: Neuroscience, Vol. 108, No 2 (2001) pp. 177-181

The orexins (orexin A and B, also known as hypocretin 1 and 2) are two recently identified neuropeptides (de Lecea et al., 1998; Sakurai et al., 1998) which are importantly implicated in the control of wakefulness (for reviews see Hungs and Mignot, 2

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c4a418544ac4b93b5ffca1ee33a92d6
https://doi.org/10.1016/s0306-4522(01)00512-7

Excitatory action of hypocretin/orexin on neurons of the central medial amygdala

Autor: A. Bisetti, Mauro Serafin, Laurence Bayer, Danièle Machard, V. Cvetkovic, Michel Muhlethaler, Barbara E. Jones

Publikováno v: Neuroscience
Neuroscience, Elsevier-International Brain Research Organization, 2006, 142 (4), pp.999-1004. <10.1016/j.neuroscience.2006.07.018>
Neuroscience, Elsevier-International Brain Research Organization, 2006, 142 (4), pp.999-1004. ⟨10.1016/j.neuroscience.2006.07.018⟩
Neuroscience, Vol. 142, No 4 (2006) pp. 999-1004

The neurons of the lateral hypothalamus that contain hypocretin/orexin (hcrt/orx) are thought to promote arousal through the excitatory action they exert on the multiple areas to which they project within the CNS. We show here that the hcrt/orx pepti

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ebad17bf4867f8fd4214da54f6be0fc6
https://hal.archives-ouvertes.fr/hal-00306413

Opposite effects of noradrenaline and acetylcholine upon hypocretin/orexin versus melanin concentrating hormone neurons in rat hypothalamic slices

Autor: Danièle Machard, Jeremy Grivel, Michel Muhlethaler, Laurence Bayer, Emmanuel Eggermann, Mauro Serafin, Barbara E. Jones

Publikováno v: Neuroscience, Vol. 130, No 4 (2005) pp. 807-811

Hypocretin/orexin (Hcrt/Orx) and melanin concentrating hormone (MCH) are peptides contained in overlapping cell groups of the lateral hypothalamus and commonly involved in regulating sleep-wake states and energy balance, though likely in different wa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56bc5d7c93bd41a21c26fd1fe177a663
https://pubmed.ncbi.nlm.nih.gov/15652980

The wake-promoting hypocretin-orexin neurons are in an intrinsic state of membrane depolarization

Autor: Benoît Saint-Mleux, Michel Muhlethaler, Laurence Bayer, Barbara E. Jones, Danièle Machard, Laurent Bernheim, Mauro Serafin, Emmanuel Eggermann

Publikováno v: Journal of Neuroscience, Vol. 23, No 5 (2003) pp. 1557-1562

Wakefulness depends on the activity of hypocretin–orexin neurons because their lesion results in narcolepsy. How these neurons maintain their activity to promote wakefulness is not known. Here, by recording for the first time from hypocretin–orex

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c5bb1748714de6600dcb6cb267b162c
https://archive-ouverte.unige.ch/unige:10241