Zobrazeno 1 - 10
of 278
pro vyhledávání: '"Danièle Bonnet-Delpon"'
La chimie du fluor est devenue un secteur important de la chimie médicinale. Depuis la découverte du fluorouracile, des fluorocorticoïdes et des fluoroquinolones, ce jeune domaine a connu de rapides et d'importants progrès durant ces quinze derni
Autor:
Raoni S. B. Gonçalves, Michael Dos Santos, Guillaume Bernadat, Danièle Bonnet-Delpon, Benoit Crousse
Publikováno v:
Beilstein Journal of Organic Chemistry, Vol 9, Iss 1, Pp 2387-2394 (2013)
Functionalized 3-trifluoromethyl-2-isoxazolines and 3-trifluoromethylisoxazoles were easily prepared from trifluoromethyl aldoxime 2 under mild conditions by using DIB as oxidant. Theoretical studies of the reactivity of trifluoroacetonitrile oxide 4
Externí odkaz:
https://doaj.org/article/2706faa52ac9452a9df158f1d3b55765
Autor:
Benoit Crousse, Guillaume Bernadat, Danièle Bonnet-Delpon, Michael Dos Santos, Raoni S B Gonçalves
Publikováno v:
Beilstein Journal of Organic Chemistry, Vol 9, Iss 1, Pp 2387-2394 (2013)
Beilstein Journal of Organic Chemistry
Beilstein Journal of Organic Chemistry
Functionalized 3-trifluoromethyl-2-isoxazolines and 3-trifluoromethylisoxazoles were easily prepared from trifluoromethyl aldoxime 2 under mild conditions by using DIB as oxidant. Theoretical studies of the reactivity of trifluoroacetonitrile oxide 4
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a911a17699708d4aae3559be6596c490
https://doaj.org/article/2706faa52ac9452a9df158f1d3b55765
https://doaj.org/article/2706faa52ac9452a9df158f1d3b55765
Publikováno v:
Journal of Fluorine Chemistry. 134:136-145
The synthesis of two series of fluorinated analogues of monoamines reuptake inhibitors based on tertiary alcohols 2-substituted morpholines scaffold has been achieved through the incorporation of fluorinated substituent into 2-substituted morpholino
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::67fcefbb82608bb7ca8de76ac84700a4
https://doi.org/10.1016/j.jfluchem.2011.02.018
https://doi.org/10.1016/j.jfluchem.2011.02.018
Publikováno v:
Journal of Fluorine Chemistry. 132:811-814
The system hexafluoroisopropanol/ethyl diazoacetate/Cu(OTf) 2 is efficient for the cyclopropanation reaction. The process is experimentally simple, and efficient with various olefins in particular terminal, disubstituted double bonds.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1130ef8fe18e9e5a6eacebf0cba95ee3
https://doi.org/10.1016/j.jfluchem.2011.05.018
https://doi.org/10.1016/j.jfluchem.2011.05.018
Publikováno v:
Org. Biomol. Chem.. 9:347-350
The synthesis of 8-aminoquinolines and 1,10-phenanthrolines with substituents in α of the nitrogen has been performed through an inverse-demanding aza-Diels-Alder (Povarov reaction) in the fluoroalcohols TFE or HFIP. This path involves simple starti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a0565a9acb6df6450132012c1e4b7f2
https://doi.org/10.1039/c0ob00496k
https://doi.org/10.1039/c0ob00496k
Autor:
Danièle Bonnet-Delpon, Thierry Milcent, Tam Nguyen Thi Ngoc, Christine Philippe, Benoit Crousse
Publikováno v:
European Journal of Organic Chemistry. 2009:5215-5223
A very easy access to new trifluoromethyl-hydroxyethylamine (Tf-HEA) derivatives by epoxide ring opening with amino-containing compounds, including aliphatic amines, aniline, aqueous ammonia, hydroxylamine, hydrazine, amino acids and a dipeptide, is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f8471c20459d6cdf83c8e7e55a3c644f
https://doi.org/10.1002/ejoc.200900578
https://doi.org/10.1002/ejoc.200900578
Autor:
Xavier Maréchal, Sandrine Ongeri, Nicolas Basse, Thierry Milcent, Danièle Bonnet-Delpon, Michèle Reboud-Ravaux, Lucia Formicola, Michelle Bouvier-Durand
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 19:83-86
We have designed novel small inhibitors of rabbit 20S proteasome using a trifluoromethyl-β-hydrazino acid scaffold. Structural variations influenced their inhibition of the three types of active sites. Proteasome inhibition at the micromolar level w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::597def17cfbfaccd18c9e4737f57e43a
https://doi.org/10.1016/j.bmcl.2008.11.012
https://doi.org/10.1016/j.bmcl.2008.11.012
Publikováno v:
Tetrahedron. 64:10497-10500
Hexafluoroisopropanol (HFIP) is explored as an effective medium for the synthesis of 2,3-unsaturated glycosides through allylic rearrangement of 3,4,6-tri-O-acetyl glucal. This metal-free, exclusively solvent-promoted Ferrier glycosylation, affords p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::08b3a0109646b9515da900ff2c9313d9
https://doi.org/10.1016/j.tet.2008.09.005
https://doi.org/10.1016/j.tet.2008.09.005