Emerging Clostridioides difficile ribotypes have divergent metabolic phenotypes.

Autor: Midani FS; Alkek Center for Metagenomics and Microbiome Research, Baylor College of Medicine, Houston, Texas, USA.; Department of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, Texas, USA., Danhof HA; Alkek Center for Metagenomics and Microbiome Research, Baylor College of Medicine, Houston, Texas, USA.; Department of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, Texas, USA., Mathew N; Alkek Center for Metagenomics and Microbiome Research, Baylor College of Medicine, Houston, Texas, USA.; Department of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, Texas, USA., Ardis CK; Alkek Center for Metagenomics and Microbiome Research, Baylor College of Medicine, Houston, Texas, USA.; Department of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, Texas, USA., Garey KW; Department of Pharmacy Practice and Translational Research, University of Houston, Houston, Texas, USA., Spinler JK; Department of Pathology and Immunology, Baylor College of Medicine, Houston, Texas, USA., Britton RA; Alkek Center for Metagenomics and Microbiome Research, Baylor College of Medicine, Houston, Texas, USA.; Department of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, Texas, USA.

Publikováno v: BioRxiv : the preprint server for biology [bioRxiv] 2024 Aug 15. Date of Electronic Publication: 2024 Aug 15.

Human intestinal organoids from Cronkhite-Canada syndrome patients reveal link between serotonin and proliferation.

Autor: Poplaski V; Program in Translational Biology and Molecular Medicine.; Department of Molecular Virology and Microbiology, and., Bomidi C; Department of Molecular Virology and Microbiology, and., Kambal A; Department of Molecular Virology and Microbiology, and., Nguyen-Phuc H; Department of Molecular Virology and Microbiology, and., Di Rienzi SC; Department of Molecular Virology and Microbiology, and.; Alkek Center for Metagenomics and Microbiome Research, Baylor College of Medicine, Houston, Texas, USA., Danhof HA; Department of Molecular Virology and Microbiology, and.; Alkek Center for Metagenomics and Microbiome Research, Baylor College of Medicine, Houston, Texas, USA., Zeng XL; Department of Molecular Virology and Microbiology, and., Feagins LA; Department of Internal Medicine, Center for Inflammatory Bowl Diseases, The University of Texas at Austin Dell Medical School, Austin, Texas, USA., Deng N; Department of Clinical Cancer Prevention, The University of Texas MD Anderson Cancer Center, Houston Texas, USA., Vilar E; Department of Clinical Cancer Prevention, The University of Texas MD Anderson Cancer Center, Houston Texas, USA., McAllister F; Department of Clinical Cancer Prevention, The University of Texas MD Anderson Cancer Center, Houston Texas, USA., Coarfa C; Dan L Duncan Comprehensive Cancer Center and.; Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, Texas, USA., Min S; Department of Inflammation and Immunity, Lerner Research Institute, Cleveland Clinic, Cleveland, Ohio, USA., Kim HJ; Department of Inflammation and Immunity, Lerner Research Institute, Cleveland Clinic, Cleveland, Ohio, USA., Shukla R; Department of Medicine, Section of Gasteroenterology and Hepatology, Baylor College of Medicine, Houston, Texas, USA., Britton R; Department of Molecular Virology and Microbiology, and.; Alkek Center for Metagenomics and Microbiome Research, Baylor College of Medicine, Houston, Texas, USA., Estes MK; Department of Molecular Virology and Microbiology, and.; Department of Medicine, Section of Gasteroenterology and Hepatology, Baylor College of Medicine, Houston, Texas, USA.; Department of Medicine, Section of Infectious Diseases, Baylor College of Medicine, Houston Texas, USA., Blutt SE; Department of Molecular Virology and Microbiology, and.

Publikováno v: The Journal of clinical investigation [J Clin Invest] 2023 Nov 01; Vol. 133 (21). Date of Electronic Publication: 2023 Nov 01.

Systems biology approach to functionally assess the Clostridioides difficile pangenome reveals genetic diversity with discriminatory power.

Autor: Norsigian CJ; Department of Bioengineering, University of California San Diego, La Jolla, CA 92039., Danhof HA; Department of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, TX 77030.; Alkek Center for Metagenomics and Microbiome Research, Baylor College of Medicine, Houston, TX 77030., Brand CK; Department of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, TX 77030.; Alkek Center for Metagenomics and Microbiome Research, Baylor College of Medicine, Houston, TX 77030., Midani FS; Department of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, TX 77030.; Alkek Center for Metagenomics and Microbiome Research, Baylor College of Medicine, Houston, TX 77030., Broddrick JT; Space Biosciences Research Branch, Space Biosciences Division, NASA Ames Research Center, Moffett Field, CA 94035., Savidge TC; Department of Pathology and Immunology, Baylor College of Medicine, Houston, TX 77030., Britton RA; Department of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, TX 77030.; Alkek Center for Metagenomics and Microbiome Research, Baylor College of Medicine, Houston, TX 77030., Palsson BO; Department of Bioengineering, University of California San Diego, La Jolla, CA 92039., Spinler JK; Space Biosciences Research Branch, Space Biosciences Division, NASA Ames Research Center, Moffett Field, CA 94035., Monk JM; Department of Bioengineering, University of California San Diego, La Jolla, CA 92039.

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2022 May 03; Vol. 119 (18), pp. e2119396119. Date of Electronic Publication: 2022 Apr 27.

The metabolic profile of Bifidobacterium dentium reflects its status as a human gut commensal.

Autor: Engevik MA; Department of Pathology and Immunology, Baylor College of Medicine, Houston, TX, USA. engevik@musc.edu.; Department of Pathology, Texas Children's Hospital, Houston, TX, USA. engevik@musc.edu.; Department of Regernative Medicine & Cell Biology, Medical University of South Carolina, SC, Charleston, USA. engevik@musc.edu., Danhof HA; Department of Virology and Microbiology, Baylor College of Medicine, Houston, TX, USA., Hall A; Department of Pathology and Immunology, Baylor College of Medicine, Houston, TX, USA.; Department of Pathology, Texas Children's Hospital, Houston, TX, USA., Engevik KA; Department of Virology and Microbiology, Baylor College of Medicine, Houston, TX, USA., Horvath TD; Department of Pathology and Immunology, Baylor College of Medicine, Houston, TX, USA.; Department of Pathology, Texas Children's Hospital, Houston, TX, USA., Haidacher SJ; Department of Pathology and Immunology, Baylor College of Medicine, Houston, TX, USA.; Department of Pathology, Texas Children's Hospital, Houston, TX, USA., Hoch KM; Department of Pathology and Immunology, Baylor College of Medicine, Houston, TX, USA.; Department of Pathology, Texas Children's Hospital, Houston, TX, USA., Endres BT; Department of Pharmacy Practice and Translational Research, University of Houston College of Pharmacy, Houston, TX, USA., Bajaj M; Department of Chemistry and Physics, and Department of Biotechnology, Alcorn State University, Lorman, MS, 39096, USA., Garey KW; Department of Pharmacy Practice and Translational Research, University of Houston College of Pharmacy, Houston, TX, USA., Britton RA; Department of Virology and Microbiology, Baylor College of Medicine, Houston, TX, USA., Spinler JK; Department of Pathology and Immunology, Baylor College of Medicine, Houston, TX, USA.; Department of Pathology, Texas Children's Hospital, Houston, TX, USA., Haag AM; Department of Pathology and Immunology, Baylor College of Medicine, Houston, TX, USA.; Department of Pathology, Texas Children's Hospital, Houston, TX, USA., Versalovic J; Department of Pathology and Immunology, Baylor College of Medicine, Houston, TX, USA.; Department of Pathology, Texas Children's Hospital, Houston, TX, USA.

Publikováno v: BMC microbiology [BMC Microbiol] 2021 May 24; Vol. 21 (1), pp. 154. Date of Electronic Publication: 2021 May 24.

Fusobacteriumnucleatum Adheres to Clostridioides difficile via the RadD Adhesin to Enhance Biofilm Formation in Intestinal Mucus.

Autor: Engevik MA; Department of Pathology and Immunology, Baylor College of Medicine, Houston, Texas; Texas Children's Microbiome Center, Department of Pathology, Texas Children's Hospital, Houston, Texas. Electronic address: melinda.engevik@bcm.edu., Danhof HA; Department of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, Texas., Auchtung J; Department of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, Texas; Department of Food Science and Technology, University of Nebraska-Lincoln, Lincoln, Nebraska., Endres BT; Department of Pharmacy Practice and Translational Research, University of Houston College of Pharmacy, Houston, Texas., Ruan W; Department of Pathology and Immunology, Baylor College of Medicine, Houston, Texas; Texas Children's Microbiome Center, Department of Pathology, Texas Children's Hospital, Houston, Texas., Bassères E; Department of Pharmacy Practice and Translational Research, University of Houston College of Pharmacy, Houston, Texas., Engevik AC; Department of Surgical Sciences, Vanderbilt University Medical Center, Nashville, Tennessee., Wu Q; Department of Pathology and Immunology, Baylor College of Medicine, Houston, Texas; Texas Children's Microbiome Center, Department of Pathology, Texas Children's Hospital, Houston, Texas., Nicholson M; Department of Pediatrics, Vanderbilt University Medical Center, Nashville, Tennessee., Luna RA; Department of Pathology and Immunology, Baylor College of Medicine, Houston, Texas; Texas Children's Microbiome Center, Department of Pathology, Texas Children's Hospital, Houston, Texas., Garey KW; Department of Pharmacy Practice and Translational Research, University of Houston College of Pharmacy, Houston, Texas., Crawford SE; Department of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, Texas., Estes MK; Department of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, Texas; Department of Surgical Sciences, Vanderbilt University Medical Center, Nashville, Tennessee., Lux R; Department of Periodontics, University of California Los Angeles School of Dentistry, Los Angeles, California., Yacyshyn MB; Department of Medicine Division of Digestive Diseases University of Cincinnati College of Medicine, Cincinnati, Ohio., Yacyshyn B; Department of Medicine Division of Digestive Diseases University of Cincinnati College of Medicine, Cincinnati, Ohio., Savidge T; Department of Pathology and Immunology, Baylor College of Medicine, Houston, Texas; Texas Children's Microbiome Center, Department of Pathology, Texas Children's Hospital, Houston, Texas., Britton RA; Department of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, Texas., Versalovic J; Department of Pathology and Immunology, Baylor College of Medicine, Houston, Texas; Texas Children's Microbiome Center, Department of Pathology, Texas Children's Hospital, Houston, Texas.

Publikováno v: Gastroenterology [Gastroenterology] 2021 Mar; Vol. 160 (4), pp. 1301-1314.e8. Date of Electronic Publication: 2020 Nov 21.