Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Danhao Xia"'
Publikováno v:
Frontiers in Aging Neuroscience, Vol 15 (2023)
BackgroundTau phosphorylation is a pathological hallmark of Alzheimer’s disease (AD). Previously, we reported that the γ-adducin 1–357 fragment is present in the brains of AD patients. However, it remains unknown how γ-adducin regulates tau pho
Externí odkaz:
https://doaj.org/article/d3f8254559dc4cc69f0c8c8a3772f75e
Autor:
Xuebing Ding, Zhi Xiang, Chi Qin, Yongkang Chen, Haiyan Tian, Lin Meng, Danhao Xia, Han Liu, Jia Song, Jun Fu, Mingming Ma, Xuejing Wang
Publikováno v:
Acta Neuropathologica Communications, Vol 9, Iss 1, Pp 1-17 (2021)
Abstract Transactive response DNA-binding protein 43 kDa (TDP-43) has been identified as the major component of ubiquitinated inclusions found in patients with sporadic amyotrophic lateral sclerosis (ALS). Increasing evidence suggests prion-like tran
Externí odkaz:
https://doaj.org/article/1fe2ee633016431db2d3e3222f11808a
Publikováno v:
Frontiers in Neuroscience, Vol 15 (2022)
Silica nanoparticles (SiO2 NPs) are increasingly investigated for their potential in drug delivery systems. However, the neurotoxicity of SiO2 NPs remains to be fully clarified. Previously SiO2 NPs have been reported to be detected in the central ner
Externí odkaz:
https://doaj.org/article/6a2b750dda5448d6a024de91b6dd726f
Autor:
Mingming Ma, Jing Yao, Yongkang Chen, Han Liu, Danhao Xia, Haiyan Tian, Xinxin Wang, Erxi Wu, Xuejing Wang, Xuebing Ding
Publikováno v:
Frontiers in Neuroscience, Vol 14 (2020)
Ross syndrome (RS) is a rare peripheral autonomic system disorder characterized by tonic pupil, hyporeflexia, and segmental anhidrosis. Neuropathological studies show that RS results from the selective cholinergic nerve degeneration. However, the cau
Externí odkaz:
https://doaj.org/article/f2d7c05b98954cbdb6feb8e6cfa38cf0
Autor:
Xin Yuan, Yingxu Yang, Chaoyang Liu, Ye Tian, Danhao Xia, Zehua Liu, Lina Pan, Min Xiong, Jing Xiong, Lanxia Meng, Zhaohui Zhang, Keqiang Ye, Haiqiang Jiang, Zhentao Zhang
Publikováno v:
Movement disorders : official journal of the Movement Disorder SocietyReferences. 37(9)
The deposition of α-synuclein (α-Syn) in the brain is the pathological hallmark of Parkinson's disease (PD). Epidemiological data indicate that exposure to fine particulate matter (≤2.5 μm in aerodynamic diameter [PM2.5]) is associated with an i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b1686a3d3b097adfc147b90533e87e6
https://pubmed.ncbi.nlm.nih.gov/36054165
https://pubmed.ncbi.nlm.nih.gov/36054165
Autor:
Wenkang Wang, Xinhui Zheng, Junfang Teng, Han Liu, Huili Cui, Danhao Xia, Chi Qin, Haiyan Tian
Publikováno v:
Journal of Molecular Neuroscience. 71:2500-2513
The pathological hallmarks of Parkinson's disease (PD), a neurodegenerative disorder, are the selective loss of dopamine neurons in the substantia nigra pars compacta (SNpc) and the presence of α-synuclein (α-syn) aggregates in the form of Lewy bod
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2581d47a4e07f81b8318b84e2371c580
https://doi.org/10.1007/s12031-021-01836-4
https://doi.org/10.1007/s12031-021-01836-4
Autor:
Xinxin Wang, Danhao Xia, Zhong-Xian Zhang, Han Liu, Chi Qin, Xuejing Wang, Haiyan Tian, Erxi Wu, Qin-Chen Cao, Beisha Tang, Junfang Teng, Jia-Yi Li, Jiu-Qi Wang, Wei Wang, Xuebing Ding, Mingming Ma, Yu Fu, Yongkang Chen, Zhi Xiang
Publikováno v:
Nature Medicine. 27:411-418
Animal studies implicate meningeal lymphatic dysfunction in the pathogenesis of neurodegenerative diseases such as Alzheimer's disease and Parkinson's disease (PD). However, there is no direct evidence in humans to support this role1-5. In this study
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ebeb41b56b03753511f673465462bc7f
https://doi.org/10.1038/s41591-020-01198-1
https://doi.org/10.1038/s41591-020-01198-1
Autor:
Danhao Xia, Lin Meng, Jia Song, Zhi Xiang, Jun Fu, Han Liu, Xuebing Ding, Chi Qin, Mingming Ma, Xuejing Wang, Haiyan Tian, Yongkang Chen
Publikováno v:
Acta Neuropathologica Communications
Acta Neuropathologica Communications, Vol 9, Iss 1, Pp 1-17 (2021)
Acta Neuropathologica Communications, Vol 9, Iss 1, Pp 1-17 (2021)
Transactive response DNA-binding protein 43 kDa (TDP-43) has been identified as the major component of ubiquitinated inclusions found in patients with sporadic amyotrophic lateral sclerosis (ALS). Increasing evidence suggests prion-like transmission
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7af5bd42d7e73586cf43c5a2cf4001da
https://doi.org/10.1186/s40478-020-01112-3
https://doi.org/10.1186/s40478-020-01112-3
Autor:
Xuebing Ding, Xiang, Zhi, Qin, Chi, Yongkang Chen, Haiyan Tian, Meng, Lin, Danhao Xia, Liu, Han, Song, Jia, Fu, Jun, Mingming Ma, Xuejing Wang
Additional file 1.Supplementary Information. Fig. S1: Distribution and expression level of hTDP-43 in different brain regions of Thy1-e (IRES-TARDBP) 1 mice and expression level of total TDP-43 in the cortex and spinal cord of different mice. Fig. S2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6557089a65cf576cc2148930329d3b9b
Autor:
Zhenyu Yue, Robert K. F. Teng, Xuebing Ding, Beisha Tang, Lebo Zhou, Jing Yao, Junfang Teng, Erxi Wu, Fengfei Wang, Yongkang Chen, Jason H. Huang, Xin Yuan, Xuejing Wang, Mingming Ma, Danhao Xia, Rui Zhang, Dongyang Teng, Zhuohua Zhang
Multiple system atrophy (MSA) is a fatal adult-onset movement disorder with autonomic failures, especially urogenital dysfunction. The neuropathological feature of MSA is the accumulation of misfolded α-synuclein (α-Syn) in the nervous system. Here
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e14b666fe16acaac9cad88ac3a945cf4