Výsledky vyhledávání - "Dangsheng Li"

Akademický článek

Macrophage deletion of Noc4l triggers endosomal TLR4/TRIF signal and leads to insulin resistance

Publikováno v: Nature Communications, Vol 12, Iss 1, Pp 1-18 (2021)

Macrophage inflammation promotes insulin resistance during diet-induced obesity. Here the authors show that macrophage NOC4L is decreased in humans and mice with obesity, that macrophage NOC4L deficiency aggravated high-fat diet induced inflammation

Externí odkaz: https://doaj.org/article/a3dfdc25ebb64e078e8726fcf246e13a

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Supplemental Materials and Methods from KRAS/NF-κB/YY1/miR-489 Signaling Axis Controls Pancreatic Cancer Metastasis

Autor: Mo-Fang Liu, Wenhui Lou, Dangsheng Li, Yingbin Liu, Yun-Ping Hu, Yong Li, Jing Cao, Ye-Fei Rong, Xiao-Hong He, Peng Yuan

This file contains Materials and Methods that are involved in the figures of the main text and supplementary information. These materials and methods include information of plasmid constructs, cell transfection and viral transduction, RNA preparation

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::239c5e8b9628520978ce010f072c4efc
https://doi.org/10.1158/0008-5472.22413540

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Data from KRAS/NF-κB/YY1/miR-489 Signaling Axis Controls Pancreatic Cancer Metastasis

Autor: Mo-Fang Liu, Wenhui Lou, Dangsheng Li, Yingbin Liu, Yun-Ping Hu, Yong Li, Jing Cao, Ye-Fei Rong, Xiao-Hong He, Peng Yuan

KRAS activation occurring in more than 90% of pancreatic ductal adenocarcinomas (PDAC) drives progression and metastasis, but the underlying mechanisms involved in these processes are still poorly understood. Here, we show how KRAS acts through infla

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::32952903fc0a4d8891c366b8ae6f5054
https://doi.org/10.1158/0008-5472.c.6508749.v1

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Data from The Nuclear Receptor Interacting Factor-3 Transcriptional Coregulator Mediates Rapid Apoptosis in Breast Cancer Cells through Direct and Bystander-Mediated Events

Autor: Herbert H. Samuels, Kathleen W. Kinnally, Sonia Martinez-Caballero, Anthony I. Vulin, Dangsheng Li, Jerome C. Nwachukwu, Sharmistha Das

We previously reported that amino acids 20 to 50 of nuclear receptor interacting factor-3 mediates rapid apoptosis in breast cancer cell lines but not in cells derived from other tissues. We refer to this short region as death domain-1 (DD1). Small i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7765752130fde6e12388b34c4988de35
https://doi.org/10.1158/0008-5472.c.6496497.v1

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Data Supplement from IL-1β-Mediated Repression of microRNA-101 Is Crucial for Inflammation-Promoted Lung Tumorigenesis

Autor: Mo-Fang Liu, Jia-Tao Lou, Dangsheng Li, Yang-Yang Xu, Shu-Jun Xu, Jing Wu, Ling-Fei Zhang, Lin Wang

Supplementary Figure S1. No significant difference in the serum levels of IL-4, IL-6, TNF-a and TGF-B between NSCLC patients and healthy controls. Supplementary Figure S2. Repression of mir-101 is involved in the tumorigenic activity of IL-1B in NSCL

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a18dd9da8b1c7f4dbb628b08b673eb3
https://doi.org/10.1158/0008-5472.22403498

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LLPS of FXR1 drives spermiogenesis by activating translation of stored mRNAs

Publikováno v: Science. 377

Postmeiotic spermatids use a unique strategy to coordinate gene expression with morphological transformation, in which transcription and translation take place at separate developmental stages, but how mRNAs stored as translationally inert messenger

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7bdf17c6a9c963feaf6894a2bf7f8a36
https://doi.org/10.1126/science.abj6647

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SIDT1-dependent absorption in the stomach mediates host uptake of dietary and orally administered microRNAs

Publikováno v: Cell Research

Dietary microRNAs have been shown to be absorbed by mammals and regulate host gene expression, but the absorption mechanism remains unknown. Here, we show that SIDT1 expressed on gastric pit cells in the stomach is required for the absorption of diet

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d97a94438be46c39040974931965cb2
http://europepmc.org/articles/PMC8026584

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piRNA-independent function of PIWIL1 as a co-activator for anaphase promoting complex/cyclosome to drive pancreatic cancer metastasis

Autor: Chun-Hui Jin, Tingbo Liang, Peng Yuan, Dangsheng Li, Jinsong Li, Mo-Fang Liu, Ye-Fei Rong, Feng Li, Yunping Hu, Shuang Zhao, Ming Rao, Wenhui Lou, Qi Yin, Yingbin Liu, Fengjuan Zhang, Tao Wei, Ligang Wu, Wei Tang

Publikováno v: Nature Cell Biology. 22:425-438

Piwi proteins are normally restricted in germ cells to suppress transposons through associations with Piwi-interacting RNAs (piRNAs), but they are also frequently activated in many types of human cancers. A great puzzle is the lack of significant ind

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::1208b750a0379474140cab0b07e66210
https://doi.org/10.1038/s41556-020-0486-z

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