Zobrazeno 1 - 10
of 64
pro vyhledávání: '"Dangshe Ma"'
Autor:
Gavin Thurston, Richard Tavare, Marcus P Kelly, Sosina Makonnen, Carlos Hickey, T Cody Arnold, Jason T Giurleo, Makenzie Danton, Christian Granados, Ishita Chatterjee, Drew Dudgeon, Marc W Retter, Dangshe Ma, William C Olson, Jessica R Kirshner
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss 1 (2021)
Externí odkaz:
https://doaj.org/article/e9dd493986824827a77c38864a866af9
Autor:
Gavin Thurston, Richard Tavare, Marcus P Kelly, Sosina Makonnen, Carlos Hickey, T Cody Arnold, Jason T Giurleo, Makenzie Danton, Christian Granados, Ishita Chatterjee, Drew Dudgeon, Marc W Retter, Dangshe Ma, William C Olson, Jessica R Kirshner
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss 1 (2021)
Background Programmed cell death protein 1/programmed death-ligand 1 (PD-1/PD-L1) blocking antibodies including cemiplimab have generated profound clinical activity across diverse cancer types. Tumorous PD-L1 expression, as assessed by immunohistoche
Externí odkaz:
https://doaj.org/article/95ca884fb1ff45408c623ba0079af2dc
Autor:
Andres E. Perez Bay, Devon Faulkner, John O. DaSilva, Tara M. Young, Katie Yang, Jason T. Giurleo, Dangshe Ma, Frank J. Delfino, William C. Olson, Gavin Thurston, Christopher Daly, Julian Andreev
Publikováno v:
Molecular Cancer Therapeutics. 22:357-370
Most antibody–drug conjugates (ADC) approved for the treatment of cancer contain protease-cleavable linkers. ADCs that traffic to lysosomes traverse highly acidic late endosomes, while ADCs that recycle to the plasma membrane traffic through mildly
Autor:
Jessica R. Kirshner, Dangshe Ma, Gavin Thurston, William C. Olson, Adam Griesemer, Akiva Mintz, Jon Popke, Lynn E. Macdonald, Andrew Murphy, Hans Gartner, Naxin Tu, Cagan Gurer, Christos A. Kyratsous, Thomas Barry, Mikhail Doubrovin, Nikunj B. Bhatt, Drew Dudgeon, Terra Potocky, Kurt H. Edelmann, Erica Ullman, Aynur Hermann, Karina Bruestle, Fanny Fredriksson, Marcus P. Kelly, Tomas C. Arnold, Carlos Hickey, Sosina Makonnen, Jason T. Giurleo, Makenzie Danton, Richard Tavaré
Assessment of immune-cell subsets within the tumor immune microenvironment is a powerful approach to better understand cancer immunotherapy responses. However, the use of biopsies to assess the tumor immune microenvironment poses challenges, includin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63a28c1ce088d993bb73c7f8fe1e2f64
https://doi.org/10.1158/2326-6066.c.6550910.v1
https://doi.org/10.1158/2326-6066.c.6550910.v1
Autor:
Alison Crawford, Jessica R. Kirshner, Gavin Thurston, Eric Smith, Dangshe Ma, Jason T. Giurleo, Pamela Krueger, Sumreen Jalal, Jennifer Finney, Makenzie Danton, Priyanka Ram, Kristin Vazzana, Olulanu H. Aina, Lauric Haber, Richard Tavaré, Danica Chiu
Supplementary figures
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90be1b820eb9b214932b71972d26d15a
https://doi.org/10.1158/2326-6066.22543602.v1
https://doi.org/10.1158/2326-6066.22543602.v1
Autor:
Jessica R. Kirshner, Dangshe Ma, Gavin Thurston, William C. Olson, Adam Griesemer, Akiva Mintz, Jon Popke, Lynn E. Macdonald, Andrew Murphy, Hans Gartner, Naxin Tu, Cagan Gurer, Christos A. Kyratsous, Thomas Barry, Mikhail Doubrovin, Nikunj B. Bhatt, Drew Dudgeon, Terra Potocky, Kurt H. Edelmann, Erica Ullman, Aynur Hermann, Karina Bruestle, Fanny Fredriksson, Marcus P. Kelly, Tomas C. Arnold, Carlos Hickey, Sosina Makonnen, Jason T. Giurleo, Makenzie Danton, Richard Tavaré
Supplementary Data from Immuno-PET Monitoring of Lymphocytes Using the CD8-Specific Antibody REGN5054
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc99ef8fb49a9843c409980f336132eb
https://doi.org/10.1158/2326-6066.22545326.v1
https://doi.org/10.1158/2326-6066.22545326.v1
Autor:
Alison Crawford, Jessica R. Kirshner, Gavin Thurston, Eric Smith, Dangshe Ma, Jason T. Giurleo, Pamela Krueger, Sumreen Jalal, Jennifer Finney, Makenzie Danton, Priyanka Ram, Kristin Vazzana, Olulanu H. Aina, Lauric Haber, Richard Tavaré, Danica Chiu
Patients with hematologic cancers have improved outcomes after treatment with bispecific antibodies that bind to CD3 on T cells and that redirect T cells toward cancer cells. However, clinical benefit against solid tumors remains to be shown. We made
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26c35e7d21e92f6019bfca787dcc9c83
https://doi.org/10.1158/2326-6066.c.6550329.v1
https://doi.org/10.1158/2326-6066.c.6550329.v1
Autor:
Puja Sapra, Hans-Peter Gerber, Christopher J. O'Donnell, Frank Loganzo, Edward Rosfjord, Judy Lucas, Lioudmila Tchistiakova, Frank Barletta, Tracey Clark, Martin Finkelstein, Hadi Falahatpisheh, Magali Guffroy, George Hu, Cynthia M. Rohde, Christine Hosselet, Jonathon Golas, Manoj B. Charati, Eric M. Bennett, Jeffrey Casavant, Jack Bikker, L. Nathan Tumey, Sujiet Puthenveetil, Kimberly Marquette, Bitha Narayanan, Dangshe Ma, Matthew Sung, Edmund I. Graziani
Effects of Systemic Administration of Free Payload Compared with Conventional HER2-vc0101 on Indicators of Bone Marrow Toxicity and Bone Marrow Payload Levels in Rats
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d432b6130242412350911c126917be78
https://doi.org/10.1158/1535-7163.22520919.v1
https://doi.org/10.1158/1535-7163.22520919.v1
Autor:
Puja Sapra, Hans-Peter Gerber, Christopher J. O'Donnell, Frank Loganzo, Edward Rosfjord, Judy Lucas, Lioudmila Tchistiakova, Frank Barletta, Tracey Clark, Martin Finkelstein, Hadi Falahatpisheh, Magali Guffroy, George Hu, Cynthia M. Rohde, Christine Hosselet, Jonathon Golas, Manoj B. Charati, Eric M. Bennett, Jeffrey Casavant, Jack Bikker, L. Nathan Tumey, Sujiet Puthenveetil, Kimberly Marquette, Bitha Narayanan, Dangshe Ma, Matthew Sung, Edmund I. Graziani
The approval of ado-trastuzumab emtansine (T-DM1) in HER2+ metastatic breast cancer validated HER2 as a target for HER2-specific antibody–drug conjugates (ADC). Despite its demonstrated clinical efficacy, certain inherent properties within T-DM1 ha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a1b894a20379dc9a76f654d4811688b
https://doi.org/10.1158/1535-7163.c.6542832
https://doi.org/10.1158/1535-7163.c.6542832
Autor:
Puja Sapra, Hans-Peter Gerber, Christopher J. O'Donnell, Frank Loganzo, Edward Rosfjord, Judy Lucas, Lioudmila Tchistiakova, Frank Barletta, Tracey Clark, Martin Finkelstein, Hadi Falahatpisheh, Magali Guffroy, George Hu, Cynthia M. Rohde, Christine Hosselet, Jonathon Golas, Manoj B. Charati, Eric M. Bennett, Jeffrey Casavant, Jack Bikker, L. Nathan Tumey, Sujiet Puthenveetil, Kimberly Marquette, Bitha Narayanan, Dangshe Ma, Matthew Sung, Edmund I. Graziani
Immunohistochemical evaluation of HER2 expression in vivo cell line and patient-derived xenograft models.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d3ff9f7c862c417038a9aae79602e4f
https://doi.org/10.1158/1535-7163.22520937
https://doi.org/10.1158/1535-7163.22520937