Zobrazeno 1 - 10
of 746
pro vyhledávání: '"Danger signal"'
Autor:
Gregor Hoppstock, Jonathan A. Lindquist, Antonia Willems, Annika Becker, Charlotte Reichardt, Ronnie Morgenroth, Saskia Stolze, Cheng Zhu, Sabine Brandt, Peter R. Mertens
Publikováno v:
Cells, Vol 13, Iss 20, p 1742 (2024)
DNA-binding protein A (DbpA) belongs to the Y-box family of cold shock domain (CSD) proteins that bind RNA/DNA and exert intracellular functions in cell stress, proliferation, and differentiation. Given the pattern of DbpA staining in inflammatory gl
Externí odkaz:
https://doaj.org/article/bd3a050ed97c40ef9790dae549f13ae9
Akademický článek
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Autor:
Elana R. Shaw, Polly Matzinger
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
The Danger Model predicts that there are some molecules that no immune system can ever be fully tolerant of, namely proteins that are only transiently expressed during times of stress, infection, or injury. Among these are the danger/alarm signals th
Externí odkaz:
https://doaj.org/article/4268debb0355461293292aa9211c50dc
Autor:
Orsolya Oravecz, Roberto Romero, Eszter Tóth, Judit Kapitány, Máté Posta, Dahiana M. Gallo, Simona W. Rossi, Adi L. Tarca, Offer Erez, Zoltán Papp, János Matkó, Nándor Gábor Than, Andrea Balogh
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
IntroductionGalectins are master regulators of maternal immune responses and placentation in pregnancy. Galectin-13 (gal-13) and galectin-14 (gal-14) are expressed solely by the placenta and contribute to maternal-fetal immune tolerance by inducing t
Externí odkaz:
https://doaj.org/article/3fcd53609d3745448dc698ede0090642
Autor:
David W. Roberts
Publikováno v:
Current Research in Toxicology, Vol 2, Iss , Pp 53-63 (2021)
There is a large body of information on testing of chemicals for skin sensitization in the murine local lymph node assay (LLNA), in which potency is quantified by the EC3 value, derived from dose-response data. This information finds use in risk asse
Externí odkaz:
https://doaj.org/article/e4afb55cfdee43439cd2be7f7290cd67
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
Externí odkaz:
https://doaj.org/article/6a96603454d847219624e4847f624251
Akademický článek
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Publikováno v:
Bezpieczeństwo Pracy. Nauka i Praktyka / Occupational Safety. Science and Practice. 572(5):21-23
Externí odkaz:
https://www.ceeol.com/search/article-detail?id=770037
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Patients treated with bioproducts (BPs) frequently develop anti-drug antibodies (ADAs) with potential neutralizing capacities leading to loss of clinical response or potential hypersensitivity reactions. Many factors can influence BP immunogenicity a
Externí odkaz:
https://doaj.org/article/25fd8291890f4d2484e79996be7ce898
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
High mobility group box 1 (HMGB1) is a highly conserved, nuclear protein present in all cell types. It is a multi-facet protein exerting functions both inside and outside of cells. Extracellular HMGB1 has been extensively studied for its prototypical
Externí odkaz:
https://doaj.org/article/67d507c834374de4a923a4300324963a