Fusion of Dendritic Cells Activating Rv2299c Protein Enhances the Protective Immunity of Ag85B-ESAT6 Vaccine Candidate against Tuberculosis

Autor: Yong Woo Back, Hyun Shik Bae, Han-Gyu Choi, Dang Thi Binh, Yeo-Jin Son, Seunga Choi, Hwa-Jung Kim

Publikováno v: Pathogens, Vol 9, Iss 11, p 865 (2020)

In Mycobacterium tuberculosis infection, naïve T cells that encounter mycobacterial antigens through dendritic cells (DCs) induce various CD4+ T-cell responses; therefore, appropriate DC activation is the key for protective immunity against tubercul

Externí odkaz: https://doaj.org/article/a9bb4010040b43eba5ece1b0fb79dfb0

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Recombinant Rv1654 protein of Mycobacterium tuberculosis induces mitochondria-mediated apoptosis in macrophage.

Autor: Lee KI; Department of Microbiology, College of Medicine, Chungnam National University, Daejeon, South Korea.; Department of Translational Immunology Institute, College of Medicine, Chungnam National University, Daejeon, South Korea., Choi S; Department of Microbiology, College of Medicine, Chungnam National University, Daejeon, South Korea.; Department of Translational Immunology Institute, College of Medicine, Chungnam National University, Daejeon, South Korea., Choi HG; Department of Microbiology, College of Medicine, Chungnam National University, Daejeon, South Korea.; Department of Translational Immunology Institute, College of Medicine, Chungnam National University, Daejeon, South Korea.; Infection Control Convergence Research Center, College of Medicine, Chungnam National University, Daejeon, South Korea., Gurmessa SK; Department of Microbiology, College of Medicine, Chungnam National University, Daejeon, South Korea.; Department of Translational Immunology Institute, College of Medicine, Chungnam National University, Daejeon, South Korea.; Infection Control Convergence Research Center, College of Medicine, Chungnam National University, Daejeon, South Korea., Dang TB; Department of Microbiology, College of Medicine, Chungnam National University, Daejeon, South Korea.; Department of Translational Immunology Institute, College of Medicine, Chungnam National University, Daejeon, South Korea.; Infection Control Convergence Research Center, College of Medicine, Chungnam National University, Daejeon, South Korea., Back YW; Department of Microbiology, College of Medicine, Chungnam National University, Daejeon, South Korea.; Department of Translational Immunology Institute, College of Medicine, Chungnam National University, Daejeon, South Korea.; Infection Control Convergence Research Center, College of Medicine, Chungnam National University, Daejeon, South Korea., Park HS; Department of Microbiology, College of Medicine, Chungnam National University, Daejeon, South Korea.; Department of Translational Immunology Institute, College of Medicine, Chungnam National University, Daejeon, South Korea.; Infection Control Convergence Research Center, College of Medicine, Chungnam National University, Daejeon, South Korea., Kim HJ; Department of Microbiology, College of Medicine, Chungnam National University, Daejeon, South Korea.; Department of Translational Immunology Institute, College of Medicine, Chungnam National University, Daejeon, South Korea.; Infection Control Convergence Research Center, College of Medicine, Chungnam National University, Daejeon, South Korea.

Publikováno v: Microbiology and immunology [Microbiol Immunol] 2021 Apr; Vol. 65 (4), pp. 178-188. Date of Electronic Publication: 2021 Mar 24.