Association of Genetic Variants in NUDT15 With Thiopurine-Induced Myelosuppression in Patients With Inflammatory Bowel Disease

Autor: Walker, GJ, Harrison, JW, Heap, GA, Voskuil, MD, Andersen, V, Anderson, CA, Ananthakrishnan, AN, Barrett, JC, Beaugerie, L, Bewshea, CM, Cole, AT, Cummings, FR, Daly, MJ, Ellul, P, Fedorak, RN, Festen, EAM, Florin, TH, Gaya, DR, Halfvarson, J, Hart, AL, Heerasing, NM, Hendy, P, Irving, PM, Jones, SE, Koskela, J, Lindsay, JO, Mansfield, JC, McGovern, D, Parkes, M, Pollok, RCG, Ramakrishnan, S, Rampton, DS, Rivas, MA, Russell, RK, Schultz, M, Sebastian, S, Seksik, P, Singh, A, So, K, Sokol, H, Subramaniam, K, Todd, A, Annese, V, Weersma, RK, Xavier, R, Ward, R, Weedon, MN, Goodhand, JR, Kennedy, NA, Ahmad, T, Holden, AL, Andrews, J, Auth, M, Babu, S, Bampton, P, Banim, P, Barnes, T, Basude, D, Beckly, J, Bell, A, Bell, S, Bhandari, P, Bloom, S, Border, D, Bredin, F, Brookes, MJ, Brown, M, Calvert, C, Campbell, D, Chanchlani, N, Chaudhary, B, Chaudhary, R, Chung-Faye, G, Colleypriest, B, Connor, S, Cooney, R, Cooper, S, Creed, TJ, Croft, N, Cullen, S, D'Amato, M, Dalal, H, Daneshmend, TK, Das, D, Delaney, M, Desilva, S, Dhar, A, Dharmasiri, S, Direkze, N, Dunckley, P, Elphick, D, Everett, SM, Feeney, M, Fell, J, Foley, S, Franke, A, Gavin, D, Gee, I, Ghosh, D, Goldsmith, C, Gorard, D, Gordon, JN, Gore, S, Green, J, Grimes, D, Hamill, G, Harbord, M, Hart, J, Hawkey, C, Iqbal, T, Ireland, A, Johnson, M, Jones, C, Kanegasundaram, S, Karban, A, Katsanos, KH, Kiparissi, F, Kirkham, S, Lal, S, Langlands, S, Lawrance, IC, Lees, CW, Lev-Tzion, R, Levison, S, Lewis, SJ, Li, A, Limdi, J, Lin, S, Lobo, A, Lockett, M, Loehry, J, MacDonald, C, MacFaul, G, Mahmood, T, Mann, S, Mawdsley, J, Mazhar, Z, McGovern, JF, McNair, A, Modi, A, Monahan, K, Moran, A, Morris, M-A, Mortimore, M, Mowat, C, Muhammed, R, Murray, CDR, Olivier, H, Orchard, TR, Panter, S, Patel, V, Phillips, R, Prasad, N, Preston, C, Radford-Smith, G, Rajasekhar, P, Roy, D, Saich, R, Satsangi, J, Schreiber, S, Sen, S, Shah, N, Shenderay, R, Shenoy, A, Shutt, J, Silverberg, M, Simmons, A, Simmons, J, Singh, S, Smith, M, Snook, JA, Sonwalker, S, Stevens, CR, Sturniolo, G, Subramanian, S, Thomas, A, Tighe, M, Torrente, F, Tremelling, M, Tsianos, E, Vani, D, Walsh, A, Watermeyer, G, Watts, D, Watts, G, Weaver, S, Wesley, E, Willmott, A, Yearsley, K, Zambar, V, Zeissig, S

Publikováno v: JAMA, 321(8), 773-785. AMER MEDICAL ASSOC

Funding Information: reported serving as a consultant for AbbVie UK; receiving honoraria from Falk and AbbVie UK; receiving grants from Crohn’s & Colitis UK and Tillott’s Pharmaceuticals; having a fellowship from the UK National Institute for Hea

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c8d78d1552e80b56aa35df97ff0b107
http://hdl.handle.net/10138/308428

Labetalol Dosing in Pregnancy: PBPK/PD and CYP2C19 Polymorphisms.

Autor: Liu XI; Division of Clinical Pharmacology, Children's National Hospital, Washington, DC, USA., Green DJ; Office of Pediatric Therapeutics, US Food and Drug Administration, Silver Spring, MD, USA., van den Anker J; Division of Clinical Pharmacology, Children's National Hospital, Washington, DC, USA., Calderon J; Division of Maternal-Fetal Medicine, Department of OB/Gyn, George Washington University, Washington, DC, USA., Ahmadzia H; Division of Maternal-Fetal Medicine, Department of OB/Gyn, George Washington University, Washington, DC, USA., Burckart GJ; Office of Clinical Pharmacology, US Food and Drug Administration, Silver Spring, MD, USA., Dallmann A; Bayer HealthCare SAS, Loos, France, on behalf of: Pharmacometrics/Modeling & Simulation, Research & Development, Pharmaceuticals, Bayer, AG, Germany.

Publikováno v: Journal of clinical pharmacology [J Clin Pharmacol] 2024 Nov; Vol. 64 (11), pp. 1443-1455. Date of Electronic Publication: 2024 Jul 08.

Clinical Features and HLA Association of 5-Aminosalicylate (5-ASA)-induced Nephrotoxicity in Inflammatory Bowel Disease.

Autor: Heap GA; IBD Pharmacogenetics, Royal Devon and Exeter Foundation Trust, Exeter, UK Precision Medicine Exeter, University of Exeter, Exeter, UK grahamheap@nhs.net., So K; IBD Pharmacogenetics, Royal Devon and Exeter Foundation Trust, Exeter, UK Precision Medicine Exeter, University of Exeter, Exeter, UK., Weedon M; Precision Medicine Exeter, University of Exeter, Exeter, UK., Edney N; Exeter Kidney Unit, Royal Devon and Exeter Foundation Trust, Exeter, UK., Bewshea C; IBD Pharmacogenetics, Royal Devon and Exeter Foundation Trust, Exeter, UK Precision Medicine Exeter, University of Exeter, Exeter, UK., Singh A; IBD Pharmacogenetics, Royal Devon and Exeter Foundation Trust, Exeter, UK Precision Medicine Exeter, University of Exeter, Exeter, UK., Annese V; University Hospital AOU, Department of Emergency, 2nd Gastroenterology Unit, Florence, Italy., Beckly J; Royal Cornwall Hospital NHS Trust, Penventinnie Lane, Truro, UK., Buurman D; Department of Gastroenterology and Hepatology, University of Groningen, Groningen, The Netherlands University Medical Center Groningen, Groningen, The Netherlands., Chaudhary R; Department of Gastroenterology, West Hertfordshire Hospitals NHS Trust, Watford General Hospital, Watford, UK., Cole AT, Cooper SC, Creed T, Cummings F, de Boer NK, D'Inca R, D'Souza R, Daneshmend TK, Delaney M, Dhar A, Direkze N, Dunckley P, Gaya DR, Gearry R, Gore S, Halfvarson J, Hart A, Hawkey CJ, Hoentjen F, Iqbal T, Irving P, Lal S, Lawrance I, Lees CW, Lockett M, Mann S, Mansfield J, Mowat C, Mulgrew CJ, Muller F, Murray C, Oram R, Orchard T, Parkes M, Phillips R, Pollok R, Radford-Smith G, Sebastian S, Sen S, Shirazi T, Silverberg M, Solomon L, Sturniolo GC, Thomas M, Tremelling M, Tsianos EV, Watts D, Weaver S, Weersma RK, Wesley E, Holden A, Ahmad T

Publikováno v: Journal of Crohn's & colitis [J Crohns Colitis] 2016 Feb; Vol. 10 (2), pp. 149-58. Date of Electronic Publication: 2015 Nov 29.

The influence of food on the oral and intravenous pharmacokinetics of a high clearance drug: a study with labetalol.

Autor: Daneshmend, TK, Roberts, CJ

Publikováno v: British Journal of Clinical Pharmacology; 1982, Vol. 14 Issue 1, p73-78, 6p

Assessment of natriuretic drugs.

Autor: Roberts, CJ, Daneshmend, TK

Publikováno v: British Journal of Clinical Pharmacology; 1981, Vol. 12 Issue 4, p465-474, 10p