Zobrazeno 1 - 10
of 119
pro vyhledávání: '"Danesh Moazed"'
Autor:
Haining Zhou, Wenzhi Feng, Juntao Yu, Tiasha A. Shafiq, Joao A. Paulo, Jiuchun Zhang, Zhenhua Luo, Steven P. Gygi, Danesh Moazed
Publikováno v:
Cell Reports, Vol 42, Iss 4, Pp 112339- (2023)
Summary: The rixosome and PRC1 silencing complexes are associated with deSUMOylating and deubiquitinating enzymes, SENP3 and USP7, respectively. How deSUMOylation and deubiquitylation contribute to rixosome- and Polycomb-mediated silencing is not ful
Externí odkaz:
https://doaj.org/article/366a72c562284fd0af51b5dbf8b37530
Publikováno v:
eLife, Vol 9 (2020)
Heterochromatic domains containing histone H3 lysine 9 methylation (H3K9me) can be epigenetically inherited independently of underlying DNA sequence. To gain insight into the mechanisms that mediate epigenetic inheritance, we used a Schizosaccharomyc
Externí odkaz:
https://doaj.org/article/81905807a78d47b6ae44e1920d3ae94d
Autor:
Nahid Iglesias, Danesh Moazed
Publikováno v:
eLife, Vol 6 (2017)
Some RNAs in mammalian cells can help to silence the DNA they are transcribed from.
Externí odkaz:
https://doaj.org/article/c16fbafc65694d2f81a431bea224601d
Autor:
Rebecca S Mathew, Antonis Tatarakis, Andrii Rudenko, Erin M Johnson-Venkatesh, Yawei J Yang, Elisabeth A Murphy, Travis P Todd, Scott T Schepers, Nertila Siuti, Anthony J Martorell, William A Falls, Sayamwong E Hammack, Christopher A Walsh, Li-Huei Tsai, Hisashi Umemori, Mark E Bouton, Danesh Moazed
Publikováno v:
eLife, Vol 5 (2016)
The SNARE-mediated vesicular transport pathway plays major roles in synaptic remodeling associated with formation of long-term memories, but the mechanisms that regulate this pathway during memory acquisition are not fully understood. Here we identif
Externí odkaz:
https://doaj.org/article/acd37fa8358f4746bfe77840b6ba1e10
Publikováno v:
eLife, Vol 5 (2016)
Heterochromatin is a conserved feature of eukaryotic chromosomes with central roles in regulation of gene expression and maintenance of genome stability. Heterochromatin formation involves spreading of chromatin-modifying factors away from initiation
Externí odkaz:
https://doaj.org/article/cffba7de26aa4a82bc05e87794d3c04e
Autor:
Haining Zhou, Chad B. Stein, Tiasha A. Shafiq, Gergana Shipkovenska, Marian Kalocsay, Joao A. Paulo, Jiuchun Zhang, Zhenhua Luo, Steven P. Gygi, Karen Adelman, Danesh Moazed
Publikováno v:
Nature. 604:167-174
Polycomb repressive complexes 1 and 2 (PRC1 and PRC2) are histone-modifying and -binding complexes that mediate the formation of facultative heterochromatin and are required for silencing of developmental genes and maintenance of cell fate1–3. Mult
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::97261721a906d1cdf375220331886211
https://doi.org/10.1038/s41586-022-04598-0
https://doi.org/10.1038/s41586-022-04598-0
Autor:
Tiasha A. Shafiq, Danesh Moazed
Heritable expression of developmental genes is mediated by autoregulating transcription factor networks (TFNs) and Polycomb repressive chromatin silencing complexes (PRCs). Whether the mammalian Polycomb pathway mediates DNA sequence-independent epig
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bd4e045f3e56234b7831cbcb5849b805
https://doi.org/10.1101/2023.02.27.530239
https://doi.org/10.1101/2023.02.27.530239
Heterochromatic domains of DNA account for a large fraction of mammalian genomes and play critical roles in silencing transposons and genes, but the mechanisms that establish and maintain these domains are not fully understood. Here we use an inducib
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bb46e45bf22f4fc44cbe7edbb333f249
https://doi.org/10.1101/2023.02.27.530221
https://doi.org/10.1101/2023.02.27.530221
Autor:
Antonis, Tatarakis, Danesh, Moazed
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2417
Neuronal miRNAs play major roles in regulation of synaptic development and plasticity. The small size of miRNAs and, in some cases, their low level of expression make their quantification and detection challenging. Here, we outline methods to quantif
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d9c76685056141d5d0b5707081f85096
https://pubmed.ncbi.nlm.nih.gov/35099787
https://pubmed.ncbi.nlm.nih.gov/35099787
Autor:
Antonis Tatarakis, Danesh Moazed
Publikováno v:
Methods in Molecular Biology ISBN: 9781071619155
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f1436b1b15dc2aa885fa2396c0d847ed
https://doi.org/10.1007/978-1-0716-1916-2_1
https://doi.org/10.1007/978-1-0716-1916-2_1