Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Daner A. Silveira"'
Autor:
Shantanu Gupta, Daner A. Silveira, Gabriel P.S. Piedade, Miguel P. Ostrowski, José Carlos M. Mombach, Ronaldo F. Hashimoto
Publikováno v:
Non-coding RNA Research, Vol 9, Iss 1, Pp 185-193 (2024)
Patients with non-small cell lung cancer (NSCLC) are often treated with chemotherapy. Poor clinical response and the onset of chemoresistance limit the anti-tumor benefits of drugs such as cisplatin. According to recent research, metastasis-associate
Externí odkaz:
https://doaj.org/article/24586555d16442aa80f64832dd5278eb
Publikováno v:
Non-coding RNA Research, Vol 8, Iss 4, Pp 605-614 (2023)
Long non-coding RNA (lncRNA) distal-less homeobox 6 antisense RNA 1 (DLX6-AS1) is elevated in a variety of cancers, including non-small cell lung cancer (NSCLC) and cervical cancer. Although it was found that the microRNA-16-5p (miR-16), which is kno
Externí odkaz:
https://doaj.org/article/699461c02e434c4480b5fcbd518adb39
Publikováno v:
Cells, Vol 12, Iss 7, p 1085 (2023)
Cell fate determination is a complex process that is frequently described as cells traveling on rugged pathways, beginning with DNA damage response (DDR). Tumor protein p53 (p53) and phosphatase and tensin homolog (PTEN) are two critical players in t
Externí odkaz:
https://doaj.org/article/4cda6be44015427f8f0b2077cf8d2863
Publikováno v:
Biology, Vol 11, Iss 4, p 480 (2022)
The long non-coding RNA X inactivate-specific transcript (lncRNA XIST) has been verified as an oncogenic gene in non-small cell lung cancer (NSCLC) whose regulatory role is largely unknown. The important tumor suppressors, microRNAs: miR-449a and miR
Externí odkaz:
https://doaj.org/article/3aa5a2f4822b4df383a002b659774dce
Publikováno v:
PLoS ONE, Vol 13, Iss 7, p e0200768 (2018)
Recent studies showed that induced microRNA-449a (miR-449a) enhances a G2/M cell cycle checkpoint arrest in prostate cancer (LNCaP) and lung adenocarcinoma cell lines. In the case of LNCaP cells, upregulated miR-449a directly downregulates c-Myc that
Externí odkaz:
https://doaj.org/article/9b56658cef0c408bb711d962e708d6ce
Autor:
Daner A Silveira, Éder Maiquel Simão, Viviane L D Mattos, Fernanda M Ribeiro, Evamberto Garcia de Góes
Publikováno v:
International Journal of Radiation Biology. 97:149-155
PURPOSE DNA damage is one of the main consequences of exposure to ionizing irradiation (IR). Recent studies indicate that IR can modulate the expression of immune system-related genes. However, the effects of IR on the expression of genes and pathway
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7e830558755eae3fc5745b05230a01e2
https://doi.org/10.1080/09553002.2021.1857454
https://doi.org/10.1080/09553002.2021.1857454
Publikováno v:
Computational biology and chemistry. 99
The Wnt pathway is important to regulate a variety of biochemical functions and can contribute to cancer development through its influence on the epithelial-mesenchymal transition (EMT). Multiple circuits have been reported to participate in the regu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05c31aeb7de3e5d7d0836a8a6c6e0dfb
https://pubmed.ncbi.nlm.nih.gov/35763962
https://pubmed.ncbi.nlm.nih.gov/35763962
Publikováno v:
FEBS Letters. 594:227-239
MicroRNA-34a-5p regulates the G1/S checkpoint in non-small cell lung cancer (NSCLC) cells. Forced expression of miR-34a-5p enhances p21 expression and promotes cellular senescence, whereas knockout of miR-34a-5p decreases senescence and increases apo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d71a5332f957ce42788933c82448999
https://doi.org/10.1002/1873-3468.13615
https://doi.org/10.1002/1873-3468.13615
Autor:
Daner A. Silveira, José C. M. Mombach
Publikováno v:
The FEBS Journal. 287:578-588
The epithelial-mesenchymal transition (EMT) is a complex mechanism in which cells undergo a transition from epithelial to mesenchymal phenotypes (there is also an intermediary hybrid state) in response to microenvironmental alterations and aberrant s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::233445185c0d0a286e79b8465b5c60db
https://doi.org/10.1111/febs.15062
https://doi.org/10.1111/febs.15062
Publikováno v:
Computers in Biology and Medicine. 104:235-240
The transforming growth factor-beta (TGF-β) pathway is involved in the regulation of cell growth and differentiation. In normal cells or in the early stages of cancer, this pathway can control proliferation stimuli by inducing cell cycle arrest or a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d99984d428fd683e02cfb2620fa01c1
https://doi.org/10.1016/j.compbiomed.2018.11.025
https://doi.org/10.1016/j.compbiomed.2018.11.025