Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Danen, Cunoosamy"'
Autor:
Mirna Chehade, Gary W. Falk, Seema Aceves, Jason K. Lee, Vinay Mehta, John Leung, Brad Shumel, Juby A. Jacob-Nara, Yamo Deniz, Paul J. Rowe, Danen Cunoosamy, Angela Khodzhayev
Publikováno v:
Gastro Hep Advances, Vol 1, Iss 5, Pp 720-732 (2022)
Eosinophilic esophagitis (EoE) is a chronic type 2 inflammatory disease characterized by an eosinophilic inflammatory infiltrate in the esophagus, leading to remodeling, stricture formation, and fibrosis. Triggered by food and aeroallergens, type 2 c
Externí odkaz:
https://doaj.org/article/bc974838088c4751b97ca2480fc9086f
Autor:
M. E. Ketelaar, K. Van De Kant, F. N. Dijk, E. M. M. Klaassen, N. Grotenboer, M. C. Nawijn, E. Dompeling, G. H. Koppelman, Clare Murray, Philip Foden, Lesley Lowe, Hannah Durrington, Adnan Custovic, Angela Simpson, Andrew J. Simpson, Dominick E. Shaw, Ana R. Sousa, Louise J. Fleming, Graham Roberts, Ioannis Pandis, Aruna T. Bansal, Julie Corfield, Scott Wagers, Ratko Djukanovic, Kian Fan Chung, Peter J. Sterk, Jorgen Vestbo, Stephen J. Fowler, S. J. Tebbutt, A. Singh, C. P. Shannon, Y. W. Kim, C. X. Yang, G. M. Gauvreau, J. M. Fitzgerald, L. P. Boulet, P. M. O’Byrne, N. Begley, A. Loudon, D. W. Ray, Selene Baos, Lucía Cremades, David Calzada, Carlos Lahoz, Blanca Cárdaba, Kewal Asosingh, Chris Lauruschkat, Kimberly Queisser, Nicholas Wanner, Kelly Weiss, Weiling Xu, Serpil Erzurum, Milena Sokolowska, Li-Yuan Chen, Yueqin Liu, Asuncion Martinez-Anton, Carolea Logun, Sara Alsaaty, Rosemarie Cuento, Rongman Cai, Junfeng Sun, Oswald Quehenberger, Aaron Armando, Edward Dennis, Stewart Levine, James Shelhamer, Kilyong Choi, Snezhina Lazova, Penka Perenovska, Dimitrinka Miteva, Stamatios Priftis, Guergana Petrova, Vassil Yablanski, Evgeni Vlaev, Hristina Rafailova, Takashi Kumae, L. J. Holmes, J. Yorke, D. M. Ryan, Sasawan Chinratanapisit, Khlongtip Matchimmadamrong, Jitladda Deerojanawong, Wissaroot Karoonboonyanan, Paskorn Sritipsukho, Vania Youroukova, Denitsa Dimitrova, Yanina Slavova, Spaska Lesichkova, Iren Tzocheva, Snezhana Parina, Svetla Angelova, Neli Korsun, Mihai Craiu, Iustina Violeta Stan, Matea Deliu, Tolga Yavuz, Matthew Sperrin, Umit M. Sahiner, Danielle Belgrave, Cansin Sackesen Sackesen, Ömer Kalayci, Petar Velikov, Tsvetelina Velikova, Ekaterina Ivanova-Todorova, Kalina Tumangelova-Yuzeir, Dobroslav Kyurkchiev, Spyridon Megremis, Bede Constantinides, Alexandros Georgios Sotiropoulos, Paraskevi Xepapadaki, David Robertson, Nikolaos Papadopoulos, Maxim Wilkinson, Craig Portsmouth, David Ray, Royston Goodacre, Anna Valerieva, Irina Bobolea, Daiana Guillén Vera, Gabriel Gonzalez-Salazar, Carlos Melero Moreno, Consuelo Fernandez Rodriguez, Natividad De Las Cuevas Moreno, R. Wang, I. Satia, R. Niven, J. A. Smith, T. Southworth, J. Plumb, V. Gupta, J. Pearson, I. Ramis, M. D. Lehner, M. Miralpeix, D. Singh, Imran Satia, Mark Woodhead, Paul O’Byrne, Jaclyn Ann Smith, Cecilia Forss, Peter Cook, Sheila Brown, Freya Svedberg, Katherine Stephenson, Margherita Bertuzzi, Elaine Bignell, Malin Enerbäck, Danen Cunoosamy, Andrew Macdonald, Caini Liu, Liang Zhu, Kiochi Fukuda, Cunjin Zhang, Suidong Ouyang, Xing Chen, Luke Qin, Suguna Rachakonda, Mark Aronica, Jun Qin, Xiaoxia Li, Marie-Chantal Larose, Anne-Sophie Archambault, Véronique Provost, Jamila Chakir, Michel Laviolette, Nicolas Flamand, Nicola Logan, Dominik Ruckerl, Judith E. Allen, Tara E. Sutherland, E. Hamelmann, C. Vogelberg, S. Goldstein, G. E. Azzi, M. Engel, R. Sigmund, S. J. Szefler, Raquel Mesquita, Luis Coentrão, Rui Veiga, José-Artur Paiva, Roberto Roncon-Albuquerque, Wendy Vargas Porras, Ana González Moreno, Jesus Macías Iglesias, Gustavo Córdova Ramos, Yesenia Peña Acevedo, Miguel Angel Tejedor Alonso, Maria Del Mar Moro Moro, Irena Krcmova, Jakub Novosad, Nicola Alexander Hanania, Marc Massanari, Heike Hecker, Eric Kassel, Craig Laforce, Kathy Rickard, Sanne Snelder, Gert-Jan Braunstahl, T. L. Jones, D. Neville, E. R. Heiden, E. Lanning, T. Brown, H. Rupani, K. S. Babu, A. J. Chauhan, M. Y. Eldegeir, A. A. Chapman, M. Ferwana, M. Caldron
Publikováno v:
Clinical and Translational Allergy, Vol 7, Iss S2, Pp 1-17 (2017)
Externí odkaz:
https://doaj.org/article/8aa220adbd1b41528cac7a760f22478f
Autor:
Ekaterina Khaleva, Anna Rattu, Chris Brightling, Andrew Bush, Apostolos Bossios, Arnaud Bourdin, Kian Fan Chung, Rekha Chaudhuri, Courtney Coleman, Sven-Erik Dahlén, Ratko Djukanovic, Antoine Deschildre, Louise Fleming, Stephen J. Fowler, Atul Gupta, Eckard Hamelmann, Simone Hashimoto, Gunilla Hedlin, Gerard H. Koppelman, Erik Melén, Clare S. Murray, Charles Pilette, Celeste Porsbjerg, Katharine C. Pike, Franca Rusconi, Clare Williams, Birgit Ahrens, Peter Alter, Freja Anckers, Maarten van den Berge, Katharina Blumchen, Guy Brusselle, Graham W. Clarke, Danen Cunoosamy, Barbro Dahlén, Piers Dixey, Andrew Exley, Urs Frey, Erol A. Gaillard, Lisa Giovannini-Chami, Jonathan Grigg, Diana Hartenstein, Liam G. Heaney, Bülent Karadag, Susanne Kaul, Inger Kull, Amelia Licari, Anke H. Maitland-van der Zee, Vera Mahler, Ann-Marie M. Schoos, Prasad Nagakumar, Jenny Negus, Hanna Nielsen, James Paton, Mariëlle Pijnenburg, Valeria Ramiconi, Sofia Romagosa Vilarnau, Stefania Principe, Niels Rutjes, Sejal Saglani, Paul Seddon, Florian Singer, Heribert Staudinger, Steve Turner, Susanne Vijverberg, Tonya Winders, Valentyna Yasinska, Graham Roberts
Publikováno v:
COMSA Working Group in the 3TR Consortium 2023, ' Development of Core Outcome Measures sets for paediatric and adult Severe Asthma (COMSA) ', The European respiratory journal, vol. 61, no. 4, 2200606 . https://doi.org/10.1183/13993003.00606-2022
BackgroundEffectiveness studies with biological therapies for asthma lack standardised outcome measures. The COMSA (Core Outcome Measures sets for paediatric and adult Severe Asthma) Working Group sought to develop Core Outcome Measures (COM) sets to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e6bceb1c4190974f07b45ab29fba474
http://www.scopus.com/inward/record.url?scp=85148996792&partnerID=8YFLogxK
http://www.scopus.com/inward/record.url?scp=85148996792&partnerID=8YFLogxK
Autor:
Jonathan Spergel, Juby Jacob-Nara, Evan Dellon, Zhen Chen, Tiffany Pela, Angela Khodzhayev, Arpita Nag, Danen Cunoosamy, Amr Radwan, Siddhesh Kamat, Eilish McCann
Publikováno v:
American Journal of Gastroenterology. 117:e282-e283
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b4592595307da324a83c96c7b04572c4
https://doi.org/10.14309/01.ajg.0000858252.26393.3a
https://doi.org/10.14309/01.ajg.0000858252.26393.3a
Autor:
Alexander Hicks, Christopher McCrae, Michael Huhn, Karl J. Staples, C. Mirella Spalluto, K Ostridge, Outi Vaarala, Danen Cunoosamy, Tom Wilkinson, Alastair Watson, Hannah Burke, Anna Freeman, Doriana Cellura
Publikováno v:
American Journal of Respiratory and Critical Care Medicine. 201:83-94
Rationale: Viral infections are major drivers of exacerbations and clinical burden in patients with asthma and chronic obstructive pulmonary disease (COPD). IFN-β is a key component of the innate immune response to viral infection. To date, studies
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::700f039d15bdc6e4084493fd46951052
https://doi.org/10.1164/rccm.201901-0214oc
https://doi.org/10.1164/rccm.201901-0214oc
Autor:
Ikuo Hirano, Marc Rothenberg, Evan Dellon, Margaret Collins, John Leung, Alain Schoepfer, Xian Sun, Julie Horowitz, Danen Cunoosamy, Kiran Patel, Arsalan Shabbir, Alexandra Hicks, Jennifer Hamilton
Publikováno v:
Journal of Allergy and Clinical Immunology. 151:AB199
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3aa20fb3a7357f8aee2cac779d2e1790
https://doi.org/10.1016/j.jaci.2022.12.623
https://doi.org/10.1016/j.jaci.2022.12.623
Autor:
Claus Bachert, Jonathan Corren, Stella E. Lee, Haixin Zhang, Sivan Harel, Danen Cunoosamy, Asif H. Khan, Juby A. Jacob‐Nara, Shahid Siddiqui, Scott Nash, Paul J. Rowe, Yamo Deniz
Publikováno v:
International forum of allergyrhinology. 12(9)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f8f90b2a044cdf386d6716609abe52b
https://pubmed.ncbi.nlm.nih.gov/34970860
https://pubmed.ncbi.nlm.nih.gov/34970860
Autor:
Marc Rothenberg, Eilish McCann, Alain Schoepfer, Xian Sun, Tiffany Pela, Angela Khodzhayev, Arpita Nag, Danen Cunoosamy, Siddhesh Kamat, Amr Radwan, Juby Jacob-Nara
Publikováno v:
American Journal of Gastroenterology. 117:e279-e279
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f11bb61b032d4cfdac40a3748871e59c
https://doi.org/10.14309/01.ajg.0000858236.23318.46
https://doi.org/10.14309/01.ajg.0000858236.23318.46
Autor:
Ziyang Nan, Xia Li, Danen Cunoosamy, Perry Matthew, Stefan Vollmer, Wenzhen Yang, Huanxi Feng, Huafei Lv
Publikováno v:
Journal of Medicinal Chemistry. 63:157-162
PROteolysis TArgeting Chimeras (PROTACs) targeting the degradation of MEK have been designed based on allosteric MEK inhibitors. Inhibition of the phosphorylation of ERK1/2 was less effective with the PROTACs than a small-molecule inhibitor; the best
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e18ab1be8a3dcef1e4ebb531a337f0d7
https://doi.org/10.1021/acs.jmedchem.9b00810
https://doi.org/10.1021/acs.jmedchem.9b00810
Autor:
Taylor S. Cohen, Lisa Öberg, Nisha Kurian, Erica De Zan, Britta Bonn, Petter Svanberg, Engin Baturcam, Gabriel Skogberg, Paul D. Smith, Outi Vaarala, Danen Cunoosamy, Stefan Vollmer
Publikováno v:
International Journal of Chronic Obstructive Pulmonary Disease. 14:2611-2624
Background Unlike p38 mitogen-activated protein Kinases (MAPK) that has been extensively studied in the context of lung-associated pathologies in COPD, the role of the dual-specificity mitogen-activated protein kinase kinase (MEK1/2) or its downstrea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::238d5e211e55ca66ace0dbf2e462b1af
https://doi.org/10.2147/copd.s211619
https://doi.org/10.2147/copd.s211619