Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Danelle Eto"'
Autor:
Marcos Steinberg, Darina Spasova, Danelle Eto, AnneMarie Pferdekamper, Phuong Nguyen, Brian Le, Zachary Naiman, Susan Murphy, Maricel Gozo, James Skipper, Taylor Ismaili, Xikui Liu, Sunil Sahdeo, Xiao Hu, Isharat Yusuf, Kristen Taylor Meadows, Laura Carter
Publikováno v:
Regular and Young Investigator Award Abstracts.
Autor:
Danelle Eto, Christopher Lao, Daniel DiToro, Burton Barnett, Tania C Escobar, Robin Kageyama, Isharat Yusuf, Shane Crotty
Publikováno v:
PLoS ONE, Vol 6, Iss 3, p e17739 (2011)
Cytokines are important modulators of lymphocytes, and both interleukin-21 (IL-21) and IL-6 have proposed roles in T follicular helper (Tfh) differentiation, and directly act on B cells. Here we investigated the absence of IL-6 alone, IL-21 alone, or
Externí odkaz:
https://doaj.org/article/f2e640a8f19c40a2ab24380f4d2b1dfb
Publikováno v:
Nature Immunology. 15:657-666
Follicular helper T cells (T(FH) cells) are responsible for effective B cell-mediated immunity, and Bcl-6 is a central factor for the differentiation of T(FH) cells. However, the molecular mechanisms that regulate the induction of T(FH) cells remain
Publikováno v:
The Journal of Immunology. 190:3049-3053
Bcl6 is required for CD4 T cell differentiation into T follicular helper cells (Tfh). In this study, we examined the role of IL-6 in early processes of in vivo Tfh differentiation, because the timing and mechanism of action of IL-6 in Tfh differentia
Autor:
Mark A. Kroenke, Michael Cho, Michela Locci, Terence M. Davidson, Danelle Eto, Shane Crotty, Elias K. Haddad
Publikováno v:
The Journal of Immunology. 188:3734-3744
Follicular helper CD4 T (Tfh) cells provide B cells with signals that are important for the generation of high-affinity Abs and immunological memory and, therefore, are critical for the protective immunity elicited by most human vaccines. Transcripti
Autor:
Danelle Eto, Tania C. Escobar, Robert J. Johnston, Christopher Lao, Laurel A. Monticelli, Robin Kageyama, Shane Crotty, Youn Soo Choi
Publikováno v:
Immunity. 34(6):932-946
Summary The nature of follicular helper CD4 + T (Tfh) cell differentiation remains controversial, including the minimal signals required for Tfh cell differentiation and the time at which Tfh cell differentiation occurs. Here we determine that Tfh ce
Autor:
Tania C. Escobar, Christopher Lao, Danelle Eto, Isharat Yusuf, Burton E. Barnett, Robin Kageyama, Shane Crotty, Daniel DiToro
Publikováno v:
PLoS ONE
PLoS ONE, Vol 6, Iss 3, p e17739 (2011)
PLoS ONE, Vol 6, Iss 3, p e17739 (2011)
Cytokines are important modulators of lymphocytes, and both interleukin-21 (IL-21) and IL-6 have proposed roles in T follicular helper (Tfh) differentiation, and directly act on B cells. Here we investigated the absence of IL-6 alone, IL-21 alone, or
Autor:
Danelle Eto, Kyle Hansen, Joe Craft, Anmol Chandele, Xuemei Dong, Sairy Hernandez, Alexander L. Dent, Shane Crotty, Amanda C. Poholek, Susan M. Kaech, Jason S. Weinstein, Jared M. Odegard
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 185(1)
Follicular helper T (TFH) cells, defined by expression of the surface markers CXCR5 and programmed death receptor-1 (PD-1) and synthesis of IL-21, require upregulation of the transcriptional repressor Bcl6 for their development and function in B cell
Autor:
Alexander L. Dent, Daniel DiToro, Robert J. Johnston, Isharat Yusuf, Joe Craft, Burton E. Barnett, Danelle Eto, Amanda C. Poholek, Shane Crotty
Publikováno v:
Science (New York, N.Y.). 325(5943)
T Follicular Helper Cell Differentiation When B cells respond to an infection, they often require help from CD4 + T cells to mount a proper response. It is thought that a subset of CD4 + effector T cells, called T follicular helper cells (T FH ), per
Autor:
J. J. Hogan, L. Beaton, Danelle Eto, Daniel DiToro, E. Kieff, Isharat Yusuf, M. L. Dustin, Hitoshi Kikutani, Joe Craft, Burton E. Barnett, Akemi Sakamoto, R. R. Ramiscal, C. G. Vinuesa, Amanda C. Poholek, Masafumi Arima, T. A. Schwickert, N. K. Verma, Takeshi Tokuhisa, Nobuaki Yoshida, Teruhito Yasui, R. J. Rigby, G. Mosialos, Gabriel D. Victora, T. Nishimura, Charles R. Mackay, D. Yu, Michel C. Nussenzweig, Christopher C. Goodnow, Ayako Inamine, K. Yada, Masahiko Hatano, M. Srivastava, Satoru Tada, Robert J. Johnston, T. Morimoto, M. A. Linterman, Alexander L. Dent, D. Kitayama, Takao Koike, Shane Crotty, Mark J. Smyth
Publikováno v:
International Immunology. 22:ii76-ii77