Zobrazeno 1 - 10
of 336
pro vyhledávání: '"Dane Wittrup"'
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss Suppl 2 (2021)
Externí odkaz:
https://doaj.org/article/dce69fa800bb466eba5247410c5007a4
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss Suppl 3 (2020)
Externí odkaz:
https://doaj.org/article/d36e83cc50884f21aaf561129327ec90
Autor:
Joseph R. Palmeri, Brianna M. Lax, Joshua M. Peters, Lauren Duhamel, Jordan A. Stinson, Luciano Santollani, Emi A. Lutz, William Pinney, Bryan D. Bryson, K. Dane Wittrup
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-19 (2024)
Abstract Although co-stimulation of T cells with agonist antibodies targeting 4-1BB (CD137) improves antitumor immune responses in preclinical studies, clinical success has been limited by on-target, off-tumor activity. Here, we report the developmen
Externí odkaz:
https://doaj.org/article/8e65e3d9cba14ba3930a59f163a199fe
Autor:
Noor Momin, K Dane Wittrup, Jordan A Stinson, Matheus Moreno M Passos Barbosa, Allison Sheen, Jordan Hampel, Elizabeth Fink, Rebecca Kamerer, Jonathan Samuelson, Rebecca Bernstein, Timothy Fan
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)
Externí odkaz:
https://doaj.org/article/507acb8003e64bd99bc67468f7c5774d
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)
Externí odkaz:
https://doaj.org/article/6dc269b32ba745f0a6c2088e09067bb6
Autor:
Naveen K Mehta, Patrick A Baeuerle, Jennifer S Michaelson, Laura Liu, K Dane Wittrup, Kristan A Meetze, Irina M Shapiro, Kavya Rakhra
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)
Externí odkaz:
https://doaj.org/article/2ffcd943e44c4402ad7217e0983a64c5
Autor:
Emi A Lutz, K Dane Wittrup, Joseph R Palmeri, Brianna M Lax, Josh M Peters, Lauren Duhamel, Jordan A Stinson, Luciano Santollani, William Pinney, Bryan D Bryson
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)
Externí odkaz:
https://doaj.org/article/1d4f4929a5304e66974b9d6a359dc8a4
Akademický článek
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Autor:
Zachariah P. Tritz, Katayoun Ayasoufi, Delaney M. Wolf, Carley A. Owens, Courtney S. Malo, Benjamin T. Himes, Cori E. Fain, Emma N. Goddery, Lila T. Yokanovich, Fang Jin, Michael J. Hansen, Ian F. Parney, Chensu Wang, Kelly D. Moynihan, Darrell J. Irvine, K. Dane Wittrup, Rosa M. Diaz Marcano, Richard G. Vile, Aaron J. Johnson
Publikováno v:
Cancer Immunology Research. :OF1-OF14
Glioblastoma (GBM) is the most common malignant brain tumor in adults, responsible for approximately 225,000 deaths per year. Despite preclinical successes, most interventions have failed to extend patient survival by more than a few months. Treatmen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7540cd53a24c6bdfa3312e808dfa839f
https://doi.org/10.1158/2326-6066.cir-22-0570
https://doi.org/10.1158/2326-6066.cir-22-0570
Autor:
Jordan A. Stinson, Allison Sheen, Noor Momin, Jordan Hampel, Rebecca Bernstein, Rebecca Kamerer, Bahaa Fadl-Alla, Jonathan Samuelson, Elizabeth Fink, Timothy M. Fan, K. Dane Wittrup
Publikováno v:
Clinical Cancer Research. :OF1-OF13
Purpose: Cytokine therapies such as IL2 and IL12 suffer from impractically small therapeutic windows driven by their on-target, off-tumor activity, limiting their clinical potential despite potent antitumor effects. We previously engineered cytokines
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::df503c8c272cc9b6e5784ef0edf395cf
https://doi.org/10.1158/1078-0432.ccr-23-0006
https://doi.org/10.1158/1078-0432.ccr-23-0006