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'Vaccines.. Where do they come from? And how do they work? By Dane Samilo

Dane Samilo, a Science and Technology Policy Fellow at the Department of Defense joined us to talk about an extremely relevant topic for all to understand. That is vaccines. He walked us through the history of vaccinations, the immune system, modern

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::22358431ccbceba9c30fca8a93c46c41

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A quantitative screen for metabolic enzyme structures reveals patterns of assembly across the yeast metabolic network

Autor: Kyle Begovich, Chalongrat Noree, Dane Samilo, James E. Wilhelm, Elena Monfort, Risa M. Broyer

Publikováno v: Molecular Biology of the Cell

Despite the proliferation of proteins that can form filaments or phase-separated condensates, it remains unclear how this behavior is distributed over biological networks. We have found that 60 of the 440 yeast metabolic enzymes robustly form structu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9b85d936d17fb6769c9345df4d184bd
https://doi.org/10.1091/mbc.e19-04-0224

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Innate Lymphocyte/Ly6C hi Monocyte Crosstalk Promotes Klebsiella Pneumoniae Clearance

Autor: James W. Keith, Dane Samilo, Eric G. Pamer, Ingrid Leiner, Rebecca A. Carter, Huizhong Xiong

Publikováno v: Cell. 165:679-689

Increasing antibiotic resistance among bacterial pathogens has rendered some infections untreatable with available antibiotics. Klebsiella pneumoniae, a bacterial pathogen that has acquired high-level antibiotic resistance, is a common cause of pulmo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f33233c516eca6aacf5dd99abeb98ec
https://doi.org/10.1016/j.cell.2016.03.017

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Collaborative data visualization for Earth Sciences with the OptIPuter

Autor: John A. Orcutt, Nut Taesombut, Bridget Smith, Graham M. Kent, Dane Samilo, Thomas Im, Atul Nayak, Xinran Wu, Andrew A. Chien, Debi Kilb

Publikováno v: Future Generation Computer Systems. 22:955-963

Collaborative visualization of large-scale datasets across geographically distributed sites is becoming increasingly important for Earth Sciences. Not only does it enhance our understanding of the geological systems, but also enables near-real-time s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e2953d9a0ffd5d4787a61bd3eea8ca7b
https://doi.org/10.1016/j.future.2006.03.023

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Transport of microspheres from the lung to the draining lymph nodes by inflammatory monocytes. (APP3P.106)

Autor: Dane Samilo, Huizhong Xiong, Rebecca Carter, Ingrid Leiner, Eric Pamer

Publikováno v: The Journal of Immunology. 194:113.7-113.7

Inflammatory monocytes (Ly6Chi CCR2hi) play a critical role in steering the course of responses against microbial infections of the lung. Lung monocytes can take up live fungi or bacteria and transport them to draining mediastinal lymph nodes (mLN).

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::dac4f4b3b6d96d4c9a4caefd1caa0895
https://doi.org/10.4049/jimmunol.194.supp.113.7

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Escherichia coli colonization restores mucosal immune tone during antibiotic treatment (MUC5P.759)

Autor: Silvia Caballero, Dane Samilo, Rebecca Carter, Eric Pamer

Publikováno v: The Journal of Immunology. 194:138.17-138.17

Molecules derived from gut-colonizing microbes contribute to intestinal homeostasis by stimulating innate immune receptors and maintaining a basal level of activation of host antimicrobial defenses. Depletion of intestinal microbes by treatment with

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::21664ea368c6837b5f0c82783dca30e0
https://doi.org/10.4049/jimmunol.194.supp.138.17

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