Zobrazeno 1 - 10
of 56
pro vyhledávání: '"Dane O. Kildsig"'
Autor:
Dane O. Kildsig, Chetan P. Pujara
Publikováno v:
Containment in the Pharmaceutical Industry ISBN: 9780429074943
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d30fabd30612733e87ea2cb2a70ba51a
https://doi.org/10.1201/9780429074943-4
https://doi.org/10.1201/9780429074943-4
Publikováno v:
AAPS PharmSciTech. 7:E133-E140
The purpose of this study was to develop an instrument (the Purdue instrument) and the corresponding methodologies to measure the electrostatic charge development (chargeability) of dry powders when they are in dynamic contact with stainless steel su
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e69de9452957b49400451a6fc60fb13b
https://doi.org/10.1208/pt0704103
https://doi.org/10.1208/pt0704103
Autor:
Vidya Swaminathan, Dane O. Kildsig
Publikováno v:
AAPS PharmSciTech. 2:73-79
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bff9a08fa916d72e05747c51bd50be91
https://doi.org/10.1208/pt020428
https://doi.org/10.1208/pt020428
Publikováno v:
Journal of Controlled Release. 48:57-66
Diffusion of small molecules in amorphous polymers has been examined by computer simulation. Diffusion coefficients of small molecules with molecular weights ranging from 16.04 (methane) to 452.50 (fluocinolone acetonide) Da in four amorphous polymer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d41bd15dec23f54d89ebe722f0273755
https://doi.org/10.1016/s0168-3659(97)00033-3
https://doi.org/10.1016/s0168-3659(97)00033-3
Autor:
Renée E. Coffman, Dane O. Kildsig
Publikováno v:
Pharmaceutical Research. 13:1460-1463
Purpose. This study examines the mechanism of hydrotropic solubilization using the riboflavin-nicotinamide system. The most commonly proposed mechanism for hydrotropic solubilization is complexation, and therefore, is investigated. Additionally, sinc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::51b3a81463fb307679236b17ef550227
https://doi.org/10.1023/a:1016011125302
https://doi.org/10.1023/a:1016011125302
Publikováno v:
Pharmaceutical Research. 10:228-232
The effects of oligomerization and liposomal entrapment on pulmonary insulin absorption were investigated in rats using an intratracheal instillation method. The results indicated that both dimeric and hexameric insulins can be rapidly absorbed into
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::415643b7ad84b14ac48591a88ab1a9e2
https://doi.org/10.1023/a:1018934810512
https://doi.org/10.1023/a:1018934810512
Publikováno v:
Drug Development and Industrial Pharmacy. 18:1599-1612
This study was designed to test a hypothesis that the esterification of the primary 6-hydroxyl groups on β-cyclodextrin (β-CD) may disrupt its crystallinity, thereby enhancing its aqueous solubility and increasing its ability to solubilize water-in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::529b2ad877ce360d60f2c9358b82e66b
https://doi.org/10.3109/03639049209040889
https://doi.org/10.3109/03639049209040889
Publikováno v:
Life Sciences. 51:1683-1689
In vitro biodegradation of insulin in rabbit and rat lung homogenates was investigated. Insulin can be sequentially metabolized into two primary fragments in rabbit lung homogenate by an aminopeptidase. The amino acid sequences of the fragments were
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d1a9364bb48155b8819895a0d8ba2df
https://doi.org/10.1016/0024-3205(92)90313-e
https://doi.org/10.1016/0024-3205(92)90313-e
Publikováno v:
International Journal of Pharmaceutics. 75:231-239
An aqueous solution of Tetronic 1508 (20–25% w/w) undergoes sol-gel transition at about 25–27°C causing a dramatic increase in bulk viscosity (4 orders of magnitude). A significant increase in viscosity would be expected to reduce the collision
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0d3031c78a0a085100e52e09e1a6c96c
https://doi.org/10.1016/0378-5173(91)90197-v
https://doi.org/10.1016/0378-5173(91)90197-v
Publikováno v:
Pharmaceutical Research. :925-929
Self-association of zinc–insulin monomers into dimers and hexamers may lead to enhanced protection of the peptide from proteolytic degradation. The present study has been undertaken to investigate the relationship, if any, between the rate of enzym
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::665b4b6628a2d60ea33691917e2d829e
https://doi.org/10.1023/a:1015820032648
https://doi.org/10.1023/a:1015820032648