Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Dandamudi V. Rao"'
Publikováno v:
Radiation Research. 153:416-427
The mechanisms by which DNA-incorporated radionuclides impart lethal damage to mammalian cells were investigated by examining the capacity of dimethyl sulfoxide (DMSO) to protect against lethal damage to Chinese hamster V79 cells caused by unbound tr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b871de196725b3507cec1d96b8f44a9e
https://doi.org/10.1667/0033-7587(2000)153[0416:pbdacd]2.0.co
https://doi.org/10.1667/0033-7587(2000)153[0416:pbdacd]2.0.co
Publikováno v:
Acta Oncologica. 39:713-720
The mechanisms by which DNA-incorporated radionuclides impart lethal damage to mammalian cells were investigated by examining the capacity of cysteamine (MEA) to protect against lethal damage to V79 cells caused by unbound tritium (3H2O), DNA-incorpo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8007117ae8822168cdb0aed0cd7736e
https://doi.org/10.1080/028418600750063776
https://doi.org/10.1080/028418600750063776
Publikováno v:
Medical Physics. 25:37-42
In our previous study we used the linear-quadratic model [J. Nucl. Med. 35, 1861 (1994)] to confirm our initial finding, based on the time-dose-fractionation model [J. Nucl. Med. 34, 1801 (1993)], that longer-lived radionuclides (e.g., 32 P , 91 Y )
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4ae9969049b30c3a6160952887ec46d
https://doi.org/10.1118/1.598171
https://doi.org/10.1118/1.598171
Publikováno v:
Investigative Radiology. 31:586-590
Rationale and objectives There is a trend toward the use of higher magnetic field strengths in magnetic resonance imaging procedures. Considering this trend and the lack of consensus on the biologic effects of static magnetic fields, it is of conside
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4860042aa46ff5acdb433dc1dcda8689
https://doi.org/10.1097/00004424-199609000-00007
https://doi.org/10.1097/00004424-199609000-00007
Autor:
Roger W. Howell, Ravi S. Harapanhalli, Amin I. Kassis, McLaughlin Lw, Adelstein Sj, Dandamudi V. Rao
Publikováno v:
Journal of Medicinal Chemistry. 39:4804-4809
An iodinated analog of the DNA-minor-groove-binding agent Hoechst 33342 has been synthesized and evaluated for DNA binding and tumor targeting. The bis-benzimidazole ring system of the title compound was constructed from the piperazinyl terminus via
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e8037d1761e4ee35c7b30e19c93c331a
https://doi.org/10.1021/jm9602672
https://doi.org/10.1021/jm9602672
Calculation of Equivalent Dose for Auger Electron Emitting Radionuclides Distributed in Human Organs
Publikováno v:
Acta Oncologica. 35:909-916
Radionuclides that emit Auger electrons can be extremely radiotoxic depending on the subcellular distribution of the radiochemical. Despite this, ICRP 60 provides no guidance in the calculation of equivalent dose H(T) for Auger electrons. The recent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64b3957bc460a2e406e5ee659688e29c
https://doi.org/10.3109/02841869609104045
https://doi.org/10.3109/02841869609104045
Publikováno v:
Medical Physics. 21:1901-1915
The biological effects of Auger-electron-emitting radionuclides can be as severe as those of alpha particles of high linear energy transfer. A great deal of effort has been expended in exploring the biological effects of Auger electron emitters. Much
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d43f5b3e949a9edc76a21ce743f0331
https://doi.org/10.1118/1.597227
https://doi.org/10.1118/1.597227
Publikováno v:
International Journal of Radiation Biology. 60:525-532
The radiotoxicity of DNA incorporated 125I in cultured pre-implantation two-cell mouse embryos was investigated and compared with external gamma-irradiation. The uptake of 125IdU in the two-cell stage embryos was determined as a function of incubatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe0fa6865b05a6772ef5e01eac063507
https://doi.org/10.1080/09553009114552361
https://doi.org/10.1080/09553009114552361
To investigate the biological effects of nonuniform distribution of radioactivity in mammalian cells, we have developed a novel three-dimensional tissue culture model. Chinese hamster V79 cells were labeled with tritiated thymidine and mixed with unl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c742f69eb0145cc64f96424845e19f3
https://europepmc.org/articles/PMC3495610/
https://europepmc.org/articles/PMC3495610/
Publikováno v:
Acta oncologica (Stockholm, Sweden). 35(7)
Dimethyl sulfoxide (DMSO) was studied for its capacity to protect against the biological effects of chronic irradiation by incorporated radionuclides. Spermatogenesis in mice was used as experimental model and spermatogonial cell survival was the bio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58b9047ae05820b7bc85ca1e2326dc0e
https://pubmed.ncbi.nlm.nih.gov/9004770
https://pubmed.ncbi.nlm.nih.gov/9004770