Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Danay Marante"'
Autor:
Jamie L. Weber, Jorge Canales, Esteban Celis, Danay Marante, Javier Pinilla-Ibarz, Alan P. Kozikowski, John Powers, Karrune Woan, Keiran S.M. Smalley, Maritza Lienlaf, Kelly Barrios, Tessa Knox, David M. Woods, Alejandro Villagra, Edward Seto, P. Perez-Villaroel, Honghai Wang, Eva Sahakian, Calvin Lee, Joel A. Bergman, Eduardo M. Sotomayor, Amod A. Sarnaik, Fengdong Cheng
Publikováno v:
Molecular Oncology. 9:1447-1457
The median survival for metastatic melanoma is in the realm of 8–16 months and there are few therapies that offer significant improvement in overall survival. One of the recent advances in cancer treatment focuses on epigenetic modifiers to alter t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::911b8bbd40eae245ff6e964c6dfd6ee5
https://doi.org/10.1016/j.molonc.2015.04.002
https://doi.org/10.1016/j.molonc.2015.04.002
Autor:
Fengdong Cheng, Jeffrey S. Weber, Danay Marante, Patricio Perez-Villarroel, Keiran S.M. Smalley, Maritza Lienlaf, Pedro Horna, Alejandro Villagra, Eduardo M. Sotomayor, Calvin Lee, Amod A. Sarnaik, Jorge Canales, Edward Seto, Tessa Knox
Publikováno v:
Cancer Research. 74:4089-4089
In spite of the progress made in the understanding of the cell biology, genetics and immunology of melanoma, the outcome for patients with advanced-stage disease has remained poor with a median survival ranging from 2-16 months. Some optimism was rec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::61d39948987085344022e2a879d54fd0
https://doi.org/10.1158/1538-7445.am2014-4089
https://doi.org/10.1158/1538-7445.am2014-4089
Autor:
Fengdong Cheng, Kelly Barrios, Calvin Lee, Patricio Perez-Villarroel, Karrune Woan, David M. Woods, Tessa Knox, Hongwei Wang, Maritza Lienlaf, Eduardo M. Sotomayor, Keiran S.M. Smalley, Alejandro Villagra, Jorge Canales, Edward Seto, Esteban Celis, Pedro Horna, Danay Marante, Jeffrey S. Weber
Publikováno v:
Cancer Research. 74:4086-4086
Histone deacetylases (HDACs), originally described as histone modifiers, have more recently been demonstrated to modify a variety of other proteins involved in diverse cellular processes unrelated to the chromatin environment. This includes the deace
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c027f2964ff5dc8e92dd0039c0fc75fc
https://doi.org/10.1158/1538-7445.am2014-4086
https://doi.org/10.1158/1538-7445.am2014-4086
Role Of Histone Deacetylase 6 (HDAC6) In The Modulation Of STAT Pathways and Immune Function Of APCs
Autor:
Calvin Lee, Jorge Canales, Eduardo M. Sotomayor, Tessa Knox, Karrune Woan, Edward Seto, Maritza Lienlaf, Patricio Perez-Villarroel, Javier Pinilla-Ibarz, Sean J. Yoder, Alejandro Villagra, Fengdong Cheng, Danay Marante
Publikováno v:
Blood. 122:1032-1032
Histone deacetylases (HDACs), originally discovered as histone modifiers are now proposed as important regulators of non-chromatin related processes, including the regulation of cellular pathways involved in the production of anti- and pro-inflammato
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dec931bb2bbfd23cc94001840b4c2345
https://doi.org/10.1182/blood.v122.21.1032.1032
https://doi.org/10.1182/blood.v122.21.1032.1032
Autor:
Eduardo M. Sotomayor, Karrune Woan, Fengdong Cheng, Tessa Knox, David M. Woods, Alejandro Villagra, Danay Marante, Jorge Canales, Hongwei Wang, Maritza Lienlaf, Patricio Perez-Villarroel, Edward Seto, Jeffrey S. Weber
Publikováno v:
Cancer Research. 73:5246-5246
There is a crescent interest to understand the cellular and molecular processes involved in the progression of melanoma. Such knowledge is crucial for the development of more efficacious treatments and improved diagnostics. Acetylation and deacetylat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c94d7b52da16a4fe1c8daee785da55f8
https://doi.org/10.1158/1538-7445.am2013-5246
https://doi.org/10.1158/1538-7445.am2013-5246
Autor:
Alejandro Villagra, Tessa Knox, Javier Pinilla-Ibarz, Fengdong Cheng, Danay Marante, Stephen Lagor, Eduardo M. Sotomayor, Patricio Perez-Villarroel, Maritza Lienlaf, Sean Yoder, V Woan Karrune, Edward Seto, Hongwei Wang
Publikováno v:
Blood. 120:1039-1039
Abstract 1039 Background Histone Deacetylases (HDACs) have divergent effects over the production of anti- and pro-inflammatory cytokines in Antigen Presenting Cells (APCs). We have previously shown that modulation of specific HDACs can alter the immu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::06af06802c565ec7a58a190deb663b7f
https://doi.org/10.1182/blood.v120.21.1039.1039
https://doi.org/10.1182/blood.v120.21.1039.1039
Autor:
Eduardo M. Sotomayor, Zi Wang, Eva Sahakian, Joel A. Bergman, Danay Marante, Alejandro Villagra, Fengdong Cheng, Jay H. Kalin, Karrune Woan, Ajaypal S. Gill, Javier Pinilla-Ibarz, Edward Seto, John Powers, Maritza Lienlaf, Jennifer Rock-Klotz, Alan P. Kozikowski, Jane L. Messina, Hongwei Wang, Alex Achille, Patricio Perez, David M. Woods, Lianet Vazquez, Jeffrey S. Weber
Publikováno v:
Cancer Research. 72:3555-3555
Melanoma is currently the fastest growing cancer in incidence according to the World Health Organization. Currently, few therapies provide significant prolongation of survival for metastatic melanoma. Immunotherapy is an attractive modality with pote
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5405f85b68e9220bba62a7d339dd037c
https://doi.org/10.1158/1538-7445.am2012-3555
https://doi.org/10.1158/1538-7445.am2012-3555
Autor:
Eduardo M. Sotomayor, Zi Wang, Jennifer Rock-Klotz, Ajay Gill, Danay Marante, Fengdong Cheng, Alejandro Villagra, Javier Pinilla-Ibarz, Karrune Woan, Oscar Merino, Hongwei Wang, Edward Seto, Lianet Vazquez
Publikováno v:
Blood. 116:1483-1483
Abstract 1483 The anti-inflammatory molecules IL-10 and STAT3 are major hurdles in our efforts to harness effective anti-tumor immunity1. Previously, we have unveiled a role for histone deacetylase 11 (HDAC11) as a negative regulator of IL-10 gene tr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::85fced37e380696dff4b621edc84a175
https://doi.org/10.1182/blood.v116.21.1483.1483
https://doi.org/10.1182/blood.v116.21.1483.1483
Autor:
John Powers, Jennifer Rock-Klotz, Maritza Lienlaf, Oscar Merino, Tessa Knox, Rongxiang Han, Fengdong Cheng, Eva Sahakian, Javier Pinilla, Alejandro Villagra, David M. Woods, Edward Seto, Susan Deng, Alan P. Kozikowski, Karrune Woan, Hongwei Wang, Danay Marante, Eduardo M. Sotomayor, Zi Wang, Joel A. Bergman, Wayne W. Hancock, Patricio Perez-Villarroel
Publikováno v:
ResearcherID
Abstract 829 APCs are critical in T-cell activation and in the induction of T-cell tolerance. Epigenetic modifications of specific genes in the APC play a key role in this process, and among them, histone deacetylases (HDACs) have emerged as key part
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b602350da86c71c93c72cd7ea973b17d
http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000313838901035&KeyUID=WOS:000313838901035
http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000313838901035&KeyUID=WOS:000313838901035
Autor:
John Powers, Fengdong Cheng, Pedro Horna, Calvin Lee, Maritza Lienlaf, Danay Marante, Eduardo M. Sotomayor, Tessa Knox, Edward Seto, Patricio Perez-Villarroel, Jorge Canales, Alejandro Villagra, Eva Sahakian
Publikováno v:
ResearcherID
Cutaneous T-cell lymphoma (CTCL) includes a spectrum of non-Hodgkin’s T-cell lymphomas. While most patients with CTCL experience non-life threatening skin symptoms, those who do progress to later stages of the disease may develop serious complicati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::110c220b6e3ac1056a15f92bf5995e26
http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000349242706133&KeyUID=WOS:000349242706133
http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000349242706133&KeyUID=WOS:000349242706133