Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Danay Cibrián"'
Autor:
Juan Manuel Domínguez, Gema Pérez-Chacón, María José Guillén, María José Muñoz-Alonso, Beatriz Somovilla-Crespo, Danay Cibrián, Bárbara Acosta-Iborra, Magdalena Adrados, Cecilia Muñoz-Calleja, Carmen Cuevas, Francisco Sánchez-Madrid, Pablo Avilés, Juan M. Zapata
Publikováno v:
Journal of Hematology & Oncology, Vol 13, Iss 1, Pp 1-15 (2020)
Abstract Background In the search for novel antibody-drug conjugates (ADCs) with therapeutic potential, it is imperative to identify novel targets to direct the antibody moiety. CD13 seems an attractive ADC target as it shows a differential pattern o
Externí odkaz:
https://doaj.org/article/38476467c1d24e7b8130be99558bbb30
Autor:
Olga Moreno-Gonzalo, Marta Ramírez-Huesca, Noelia Blas-Rus, Danay Cibrián, María Laura Saiz, Inmaculada Jorge, Emilio Camafeita, Jesús Vázquez, Francisco Sánchez-Madrid
Publikováno v:
PLoS Pathogens, Vol 13, Iss 12, p e1006799 (2017)
Recent evidence on HDAC6 function underlines its role as a key protein in the innate immune response to viral infection. However, whether HDAC6 regulates innate immunity during bacterial infection remains unexplored. To assess the role of HDAC6 in th
Externí odkaz:
https://doaj.org/article/892c857570b44b8eb7cedf608fdbe6cc
Autor:
Jorge Berlanga-Acosta, Dania Vázquez-Blomquist, Danay Cibrián, Yssel Mendoza, María E Ochagavía, Jamilet Miranda, José Suárez, Yolanda González-Ferrer, José M Vila, Angel Abreu, Dayana Ugarte-Moreno, Yolanda Cruz, Ivon Howland, Rosa Coro-Antich, Olga S León, Ricardo Bringas, Diana García del Barco, Karelia Cosme-Díaz, Daniel Palenzuela, Julio R Fernández, Marcelo Nazabal, Isabel Guillén, Alberto Cintado, Lidia Inés, Ernesto López-Mola, Gerardo E Guillén-Nieto
Publikováno v:
Biotecnología Aplicada, Vol 29, Iss 2, Pp 60-72
Tissue fibrosis is a leading cause of morbidity and mortality. Current treatments for conditions such as hepatic fibrosis have been unsuccessful. The growth hormone relasing peptide 6 (GHRP6) is endowed with cardioprotective actions but its antifibro
Externí odkaz:
https://doaj.org/article/6312de42be364b7fbd319f6cf96961e7
Autor:
Domínguez, Juan Manuel, Pérez-Chacón, Gema, Guillén, María José, Muñoz-Alonso, María José, Somovilla-Crespo, Beatriz, Danay Cibrián, Acosta-Iborra, Bárbara, Adrados, Magdalena, Muñoz-Calleja, Cecilia, Cuevas, Carmen, Sánchez-Madrid, Francisco, Avilés, Pablo, Zapata, Juan M.
Additional file 1: Supplementary Materials and Methods, Table S1. Anti-proliferative activity of PM050489 in CD13 positive and negative cell lines. Figure S1. Immunohistochemistry analysis of CD13 expression in tumor samples. Figure S2. Chromatograph
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a72d0970b0d6a29c70cf8fc82d19171
Autor:
Jorge Berlanga-Acosta, Danay Cibrian, Juan Valiente-Mustelier, José Suárez-Alba, Ariana García-Ojalvo, Viviana Falcón-Cama, Baohong Jiang, Linlin Wang, Gerardo Guillén-Nieto
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
Introduction: Dilated cardiomyopathy (DCM) is a fatal myocardial condition with ventricular structural changes and functional deficits, leading to systolic dysfunction and heart failure (HF). DCM is a frequent complication in oncologic patients recei
Externí odkaz:
https://doaj.org/article/0bb22ff21fcc47d583165470d855e6f9
Autor:
Antonio Bouthelier, Lucía Fernández-Arroyo, Claudia Mesa-Ciller, Danay Cibrian, Noa Beatriz Martín-Cófreces, Raquel Castillo-González, Macarena Calero, Diego Herráez-Aguilar, Andrea Guajardo-Grence, Ana María Pacheco, Ana Marcos-Jiménez, Borja Quiroga, Marta Morado, Francisco Monroy, Cecilia Muñoz-Calleja, Francisco Sánchez-Madrid, Andrés A. Urrutia, Julián Aragonés
Publikováno v:
iScience, Vol 26, Iss 1, Pp 105739- (2023)
Summary: Inhibition of the heterodimeric amino acid carrier SLC7A5/SLC3A2 (LAT1/CD98) has been widely studied in tumor biology but its role in physiological conditions remains largely unknown. Here we show that the SLC7A5/SLC3A2 heterodimer is consti
Externí odkaz:
https://doaj.org/article/9f88a225d2a34608ab1186ab95692670
Autor:
Danay Cibrián-Vera, Hortensia de la Fuente, Pilar Navarro, Gloria Martínez del Hoyo, Aranzazu Cruz-Adalia, Jesús Vázquez, Daniel Pérez-Hernández, Pilar Martín, Marta Ramírez-Huesca, Ricardo Gutiérrez-Gallego, Francisco Sánchez-Madrid, Pedro Bonay
Publikováno v:
Biblos-e Archivo. Repositorio Institucional de la UAM
instname
Digital.CSIC. Repositorio Institucional del CSIC
Europe PubMed Central
instname
Digital.CSIC. Repositorio Institucional del CSIC
Europe PubMed Central
CD69 is involved in immune cell homeostasis, regulating the T cell-mediated immune response through the control of Th17 cell differentiation. However, natural ligands for CD69 have not yet been described. Using recombinant fusion proteins containing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77584fcd26136ae0940d5d7777b0f659
http://hdl.handle.net/10486/667325
http://hdl.handle.net/10486/667325
Autor:
Pedro Rodríguez-Jiménez, Lola Fernández-Messina, María C. Ovejero-Benito, Pablo Chicharro, Paula Vera-Tomé, Alicia Vara, Danay Cibrian, Pedro Martínez-Fleta, María Jiménez-Fernández, Inés Sánchez-García, Mar Llamas-Velasco, Francisco Abad-Santos, Francisco Sánchez-Madrid, Esteban Dauden, Hortensia de la Fuente
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
Abstract The interplay between T cells, dendritic cells and keratinocytes is crucial for the development and maintenance of inflammation in psoriasis. GADD45 proteins mediate DNA repair in different cells including keratinocytes. In the immune system
Externí odkaz:
https://doaj.org/article/29198615589e4c7bba2b3db9df1d1000
Publikováno v:
Frontiers in Immunology, Vol 12 (2022)
Externí odkaz:
https://doaj.org/article/cabd8944c06748c888196bc78dcef8b8
Autor:
Candelas Álvarez-Salamero, Raquel Castillo-González, Gloria Pastor-Fernández, Isabel R Mariblanca, Jesús Pino, Danay Cibrian, María N Navarro
Publikováno v:
PLoS Biology, Vol 18, Iss 3, p e3000646 (2020)
Interleukin 23 (IL-23) triggers pathogenic features in pro-inflammatory, IL-17-secreting T cells (Th17 and Tγδ17) that play a key role in the development of inflammatory diseases. However, the IL-23 signaling cascade remains largely undefined. Here
Externí odkaz:
https://doaj.org/article/eb54bca871fb4184a9059c76431e09c1