Zobrazeno 1 - 10
of 55
pro vyhledávání: '"Dana W. Y. Tsui"'
Autor:
Mathias Cardner, Francesco Marass, Erika Gedvilaite, Julie L. Yang, Dana W. Y. Tsui, Niko Beerenwinkel
Publikováno v:
BMC Bioinformatics, Vol 24, Iss 1, Pp 1-9 (2023)
Abstract Background Liquid biopsy is a minimally-invasive method of sampling bodily fluids, capable of revealing evidence of cancer. The distribution of cell-free DNA (cfDNA) fragment lengths has been shown to differ between healthy subjects and canc
Externí odkaz:
https://doaj.org/article/bbde033bd9784290b10587b1b299e0ba
Autor:
Andi Flory, Lisa McLennan, Betsy Peet, Marissa Kroll, Deirdre Stuart, Devon Brown, Kathy Stuebner, Brenda Phillips, Brenda L. Coomber, J. Paul Woods, Mairin Miller, Chelsea D. Tripp, Amber Wolf‐Ringwall, Kristina M. Kruglyak, Angela L. McCleary‐Wheeler, Ashley Phelps‐Dunn, Lilian K. Wong, Chelsea D. Warren, Gina Brandstetter, Michelle C. Rosentel, Lauren R. DiMarzio, Allison L. O'Kell, Todd A. Cohen, Daniel S. Grosu, Jason Chibuk, Dana W. Y. Tsui, Ilya Chorny, Jill M. Rafalko
Publikováno v:
Journal of Veterinary Internal Medicine, Vol 37, Iss 1, Pp 258-267 (2023)
Abstract Background Guidelines‐driven screening protocols for early cancer detection in dogs are lacking, and cancer often is detected at advanced stages. Hypothesis/Objectives To examine how cancer typically is detected in dogs and whether the add
Externí odkaz:
https://doaj.org/article/d371ca1a414843748846f7200db24ee1
Autor:
Jonathan C. M. Wan, Dennis Stephens, Lingqi Luo, James R. White, Caitlin M. Stewart, Benoît Rousseau, Dana W. Y. Tsui, Luis A. Diaz
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-12 (2022)
Detection of mutational signatures in cell-free DNA (cfDNA) is challenging due to low sequence coverage and low mutant allele fractions. Here, the authors identify mutational signatures in plasma whole genome sequencing of cancer patients and use mac
Externí odkaz:
https://doaj.org/article/0be4d40d73634081ab710d857edeeeba
Autor:
David H Abramson, Diana L Mandelker, A Rose Brannon, Ira J Dunkel, Ryma Benayed, Michael F Berger, Maria E Arcila, Marc Ladanyi, Danielle Novetsky Friedman, Gowtham Jayakumaran, Monica S Diosdado, Melissa A Robbins, Dianna Haggag-Lindgren, Neerav Shukla, Michael F Walsh, Prachi Kothari, Dana W Y Tsui, Jasmine H Francis
Publikováno v:
PLoS ONE, Vol 18, Iss 2, p e0271505 (2023)
Cell free DNA (cfDNA) and circulating tumor cell free DNA (ctDNA) from blood (plasma) are increasingly being used in oncology for diagnosis, monitoring response, identifying cancer causing mutations and detecting recurrences. Circulating tumor RB1 DN
Externí odkaz:
https://doaj.org/article/84031ebaf17544d78246236a3ffbf765
Autor:
Jill M. Rafalko, Kristina M. Kruglyak, Angela L. McCleary-Wheeler, Vidit Goyal, Ashley Phelps-Dunn, Lilian K. Wong, Chelsea D. Warren, Gina Brandstetter, Michelle C. Rosentel, Lauren DiMarzio, Lisa M. McLennan, Allison L. O’Kell, Todd A. Cohen, Daniel S. Grosu, Jason Chibuk, Dana W. Y. Tsui, Ilya Chorny, Andi Flory
Publikováno v:
PLoS ONE, Vol 18, Iss 2 (2023)
The goal of cancer screening is to detect disease at an early stage when treatment may be more effective. Cancer screening in dogs has relied upon annual physical examinations and routine laboratory tests, which are largely inadequate for detecting p
Externí odkaz:
https://doaj.org/article/850178916d354a938894d43ace134f57
Autor:
Kristina M. Kruglyak, Allison L. O’Kell, Todd A. Cohen, Maggie A. Marshall, Carlos A. Ruiz-Perez, Francesco Marass, John A. Tynan, Susan C. Hicks, Katherine M. Lytle, Ashley Phelps-Dunn, Gina Brandstetter, Chelsea D. Warren, Lauren R. DiMarzio, Michelle C. Rosentel, Lilian K. Wong, Lisa M. McLennan, Jill M. Rafalko, Daniel S. Grosu, Jason Chibuk, Ilya Chorny, Angela L. McCleary-Wheeler, Andi Flory, Dana W. Y. Tsui
Publikováno v:
Veterinary Sciences, Vol 10, Iss 7, p 455 (2023)
Age-related somatic genomic alterations in hematopoietic cell lines have been well characterized in humans; however, this phenomenon has not been well studied in other species. Next-generation sequencing-based liquid biopsy testing for cancer detecti
Externí odkaz:
https://doaj.org/article/3a9289a6ca7a4026b2f0d1f4db2b7333
Autor:
Dana W. Y. Tsui, Michael L. Cheng, Maha Shady, Julie L. Yang, Dennis Stephens, Helen Won, Preethi Srinivasan, Kety Huberman, Fanli Meng, Xiaohong Jing, Juber Patel, Maysun Hasan, Ian Johnson, Erika Gedvilaite, Brian Houck-Loomis, Nicholas D. Socci, S. Duygu Selcuklu, Venkatraman E. Seshan, Hongxin Zhang, Debyani Chakravarty, Ahmet Zehir, Ryma Benayed, Maria Arcila, Marc Ladanyi, Samuel A. Funt, Darren R. Feldman, Bob T. Li, Pedram Razavi, Jonathan Rosenberg, Dean Bajorin, Gopa Iyer, Wassim Abida, Howard I. Scher, Dana Rathkopf, Agnes Viale, Michael F. Berger, David B. Solit
Publikováno v:
Genome Medicine, Vol 13, Iss 1, Pp 1-15 (2021)
Abstract Background Cell-free DNA (cfDNA) profiling is increasingly used to guide cancer care, yet mutations are not always identified. The ability to detect somatic mutations in plasma depends on both assay sensitivity and the fraction of circulatin
Externí odkaz:
https://doaj.org/article/a175329a098b4151983ca7a727781ce0
Autor:
Andi Flory, Kristina M. Kruglyak, John A. Tynan, Lisa M. McLennan, Jill M. Rafalko, Patrick Christian Fiaux, Gilberto E. Hernandez, Francesco Marass, Prachi Nakashe, Carlos A. Ruiz-Perez, Donna M. Fath, Thuy Jennings, Rita Motalli-Pepio, Kate Wotrang, Angela L. McCleary-Wheeler, Susan Lana, Brenda Phillips, Brian K. Flesner, Nicole F. Leibman, Tracy LaDue, Chelsea D. Tripp, Brenda L. Coomber, J. Paul Woods, Mairin Miller, Sean W. Aiken, Amber Wolf-Ringwall, Antonella Borgatti, Kathleen Kraska, Christopher B. Thomson, Alane Kosanovich Cahalane, Rebecca L. Murray, William C. Kisseberth, Maria A. Camps-Palau, Franck Floch, Claire Beaudu-Lange, Aurélia Klajer-Peres, Olivier Keravel, Luc-André Fribourg-Blanc, Pascale Chicha Mazetier, Angelo Marco, Molly B. McLeod, Erin Portillo, Terry S. Clark, Scott Judd, C. Kirk Feinberg, Marie Benitez, Candace Runyan, Lindsey Hackett, Scott Lafey, Danielle Richardson, Sarah Vineyard, Mary Tefend Campbell, Nilesh Dharajiya, Taylor J. Jensen, Dirk van den Boom, Luis A. Diaz, Daniel S. Grosu, Arthur Polk, Kalle Marsal, Susan Cho Hicks, Katherine M. Lytle, Lauren Holtvoigt, Jason Chibuk, Ilya Chorny, Dana W. Y. Tsui
Publikováno v:
PLoS ONE, Vol 17, Iss 4 (2022)
Cancer is the leading cause of death in dogs, yet there are no established screening paradigms for early detection. Liquid biopsy methods that interrogate cancer-derived genomic alterations in cell-free DNA in blood are being adopted for multi-cancer
Externí odkaz:
https://doaj.org/article/43858f4c31a245f1a4b65cc45a0d8378
Autor:
Allison L. O’Kell, Katherine M. Lytle, Todd A. Cohen, Lilian K. Wong, Emily Sandford, Jill M. Rafalko, Gina Brandstetter, Lauren R. DiMarzio, Ashley Phelps-Dunn, Michelle C. Rosentel, Chelsea D. Warren, Angela L. McCleary-Wheeler, Patrick C. Fiaux, Francesco Marass, Maggie A. Marshall, Carlos A. Ruiz-Perez, Kristina M. Kruglyak, John A. Tynan, Susan C. Hicks, Daniel S. Grosu, Jason Chibuk, Ilya Chorny, Dana W. Y. Tsui, Andi Flory
Publikováno v:
Journal of the American Veterinary Medical Association. :1-10
OBJECTIVE To review ordering patterns, positivity rates, and outcome data for a subset of consecutive samples submitted for a commercially available, blood-based multicancer early-detection liquid biopsy test for dogs using next-generation sequencing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::317b4ee0a610c58111789eab511a9d3f
https://doi.org/10.2460/javma.22.11.0526
https://doi.org/10.2460/javma.22.11.0526
Autor:
Jason Chibuk, Andi Flory, Kristina M. Kruglyak, Nicole Leibman, Alexis Nahama, Nilesh Dharajiya, Dirk van den Boom, Taylor J. Jensen, Jeffrey S. Friedman, M. Richard Shen, Francisco Clemente-Vicario, Ilya Chorny, John A. Tynan, Katherine M. Lytle, Lauren E. Holtvoigt, Muhammed Murtaza, Luis A. Diaz, Dana W. Y. Tsui, Daniel S. Grosu
Publikováno v:
Frontiers in Veterinary Science, Vol 8 (2021)
Cancer is the leading cause of death in dogs, in part because many cases are identified at an advanced stage when clinical signs have developed, and prognosis is poor. Increased understanding of cancer as a disease of the genome has led to the introd
Externí odkaz:
https://doaj.org/article/1a670dcb55b249c9b2b7661f3b596c77