Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Dana V. Foss"'
Publikováno v:
FEBS Open Bio, Vol 9, Iss 6, Pp 1042-1051 (2019)
Viral suppressors of RNA silencing (VSRSs) are a diverse group of viral proteins that have evolved to disrupt eukaryotic RNA silencing pathways, thereby contributing to viral pathogenicity. The p19 protein is a VSRS that selectively binds to short in
Externí odkaz:
https://doaj.org/article/5e8d095a74aa4108b2c233abd8dbfd4e
Autor:
Dana V. Foss, Joseph J. Muldoon, David N. Nguyen, Daniel Carr, Srishti U. Sahu, John M. Hunsinger, Stacia K. Wyman, Netravathi Krishnappa, Rima Mendonsa, Elaine V. Schanzer, Brian R. Shy, Vivasvan S. Vykunta, Vincent Allain, Zhongmei Li, Alexander Marson, Justin Eyquem, Ross C. Wilson
Publikováno v:
Nature biomedical engineering, vol 7, iss 5
CRISPR-mediated genome editing of primary human lymphocytes is typically carried out via electroporation, which can be cytotoxic, cumbersome and costly. Here we show that the yields of edited primary human lymphocytes can be increased substantially b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37d98d71ebdbd567262a88ba896fa4ca
https://escholarship.org/uc/item/0d8552gt
https://escholarship.org/uc/item/0d8552gt
Publikováno v:
Transfusion. 59:1389-1399
Clustered regularly interspaced short palindromic repeats (CRISPR)-driven genome editing has rapidly transformed preclinical biomedical research by eliminating the underlying genetic basis of many diseases in model systems and facilitating the study
Publikováno v:
Biochemistry. 58(33)
The p19 viral suppressor of RNA silencing protein has useful applications in biotechnology due to its high affinity for binding to small RNAs such as small interfering RNAs (siRNAs). Also, its applications for the study and modulation of microRNAs ar
Autor:
Dana V Foss, John Paul Pezacki, Julie Delcorde, Peter G. Schultz, Joanna Fréderique De Graaf, Noreen Ahmed, Nadine Ahmed
Publikováno v:
Bioconjugate chemistry. 29(12)
Endogenously expressed noncoding RNAs are regulators of mRNA translation and affect diverse biological pathways spanning embryogenesis to cholesterol and fatty acid metabolism. Recently, microRNAs have become an important therapeutic target with stra
Publikováno v:
Transfusion. 59(4)
Clustered regularly interspaced short palindromic repeats (CRISPR)-driven genome editing has rapidly transformed preclinical biomedical research by eliminating the underlying genetic basis of many diseases in model systems and facilitating the study