Zobrazeno 1 - 10
of 43
pro vyhledávání: '"Dana Napier"'
Autor:
Charles A. Kunos, Denise Fabian, Dana Napier, Mark S. Stonecypher, Ravyn M. Duncan, Jason Hurt
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
Introduction212Pb-DOTAM-GRPR1 is a pharmaceutical radioimmunoconjugate consisiting of an α-particle-emitting radionuclide lead-212 (212Pb), a metal chelator DOTAM (1,4,7,10-tetrakis(carbamoylmethyl)-1,4,7,10-tetraazacyclododecane), and a gastrin-rel
Externí odkaz:
https://doaj.org/article/1f994eafa50845afadb2184a8dcfdccb
Autor:
Charles A. Kunos, Denise Fabian, Dava W. Piecoro, Dana Napier, Rachel W. Miller, Frederick R. Ueland
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
IntroductionHigh-risk human epidermal growth factor receptor 2 (HER2)-positive adenocarcinomas associate with early recurrence and death, prompting consideration of novel radiotherapeutic options like a trastuzumab-linked thorium-227 alpha-particle e
Externí odkaz:
https://doaj.org/article/661a6777ef424189944747dbe8f4b45e
Autor:
Yadi Wu, Yu Wang, Yiwei Lin, Yajuan Liu, Yifan Wang, Jianhang Jia, Puja Singh, Young-In Chi, Chi Wang, Chenfang Dong, Wei Li, Min Tao, Dana Napier, Qiuying Shi, Jiong Deng, B Mark Evers, Binhua P. Zhou
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-16 (2017)
Snail1 is a key factor controlling epithelial-to-mesenchymal transition and cancer metastasis. While the E3 ligases responsible for Snail1 ubiquitination and degradation have been defined, the deubiquitinating enzyme is unknown. Here Zhou and colleag
Externí odkaz:
https://doaj.org/article/c2fd696d39334f5f9f3e271c34495a71
Autor:
Jeremy Johnson, Zeta Chow, Dana Napier, Eun Lee, Heidi L. Weiss, B. Mark Evers, Piotr Rychahou
Publikováno v:
Cells, Vol 9, Iss 5, p 1253 (2020)
Triple negative breast cancer (TNBC) is the most aggressive breast cancer subtype and is characterized by poor survival. Radiotherapy plays an important role in treating TNBC. The purpose of this study was to determine whether inhibiting the AMP-acti
Externí odkaz:
https://doaj.org/article/8d8fc5d4fff04679b50a84e6c01a36a6
Autor:
Rachel C. Angers, Tanya S. Seward, Dana Napier, Michael Green, Edward Hoover, Terry Spraker, Katherine O’Rourke, Aru Balachandran, Glenn C. Telling
Publikováno v:
Emerging Infectious Diseases, Vol 15, Iss 5, Pp 696-703 (2009)
Chronic wasting disease (CWD) is a contagious, fatal prion disease of deer and elk that continues to emerge in new locations. To explore the means by which prions are transmitted with high efficiency among cervids, we examined prion infectivity in th
Externí odkaz:
https://doaj.org/article/65a626abe3574b3dbc85f2fe6b1f6144
Autor:
Yanquan Zhang, Ka Will Fong, Fengyi Mao, Ruixin Wang, Yifan Kong, Chaohao Li, Jinghui Liu, Zhiguo Li, Derek B. Allison, Dana Napier, Daheng Li, Jinpeng Liu, Chi Wang, Yeqing Zhang, Guangbing Li, Xiaoqi Liu
Publikováno v:
Cancer Research. 83:4992-4992
Background: Bromodomain-containing protein 4 (BRD4) has been widely studied as an attractive therapeutic target of prostate cancer (PCa). Currently, a number of BRD4 inhibitors or degraders have been discovered. However, recent studies revealed that
Autor:
Daheng He, Yanquan Zhang, Chi Wang, Changkun Huang, Xiaoqi Liu, Karrie L. Jones, Yifan Kong, Xiongjian Rao, Zhuangzhuang Zhang, Eun Y. Lee, Chaohao Li, Lijun Cheng, Dana Napier, Jinpeng Liu, Jinghui Liu
Publikováno v:
Oncogene
Blockade of programmed death-ligand 1 (PD-L1) by therapeutic antibodies has shown to be a promising strategy in cancer therapy, yet clinical response in many types of cancer, including prostate cancer (PCa), is limited. Tumor cells secrete PD-L1 thro
Autor:
Chang Li, Ji Tae Kim, Jinhwan Kim, Qingding Wang, Heidi L. Weiss, Eun Lee, B. Mark Evers, Dana Napier
Publikováno v:
Free Radic Biol Med
The disturbance of strictly regulated self-regeneration in mammalian intestinal epithelium is associated with various intestinal disorders, particularly inflammatory bowel diseases (IBDs). TNFα, which plays a critical role in the pathogenesis of IBD
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22718b14163f8348a070e131fdf01947
https://europepmc.org/articles/PMC8355065/
https://europepmc.org/articles/PMC8355065/
Autor:
Xucai Zheng, Xinlan Lu, Hai Qian, Olivier Thibault, Binhua P. Zhou, Chi Wang, Li Chen, Shuixiang He, Yang Zhang, Dongping Wei, Nevean Hamad, Chunming Liu, Rolf J. Craven, Jian-An Huang, Li Xu, Yadi Wu, Yueyin Pan, Jieming Li, Xiuwei H. Yang, Junfeng Shi, Helen Yang, Dana Napier, Zeyi Liu, Xiaowei Wei, Bingwei Xu
Publikováno v:
Cellular Oncology (Dordrecht)
Purpose Stemming from a myriad of genetic and epigenetic alterations, triple-negative breast cancer (TNBC) is tied to poor clinical outcomes and aspires for individualized therapies. Here we investigated the therapeutic potential of co-inhibiting int
Autor:
Dana Napier, Eun Y. Lee, Zeta Chow, Piotr G. Rychahou, B. Mark Evers, Heidi L. Weiss, Jeremy Johnson
Publikováno v:
Cells, Vol 9, Iss 1253, p 1253 (2020)
Cells
Volume 9
Issue 5
Cells
Volume 9
Issue 5
Triple negative breast cancer (TNBC) is the most aggressive breast cancer subtype and is characterized by poor survival. Radiotherapy plays an important role in treating TNBC. The purpose of this study was to determine whether inhibiting the AMP-acti