Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Dana N. Thornlow"'
Autor:
Dana N. Thornlow, Andrew N. Macintyre, Thomas H. Oguin, Amelia B. Karlsson, Erica L. Stover, Heather E. Lynch, Gregory D. Sempowski, Aaron G. Schmidt
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Influenza virus alters glycosylation patterns on its surface exposed glycoproteins to evade host adaptive immune responses. The viral hemagglutinin (HA), in particular the H3 subtype, has increased its overall surface glycosylation since its introduc
Externí odkaz:
https://doaj.org/article/1d4b5aa96ea545c7a412bb252d295dee
Autor:
Matthew P. DeLisa, Christopher A. Alabi, Matthew J. Paszek, Judith H. Merritt, Jordan L. Fuller, Michaela A. Jones, Dana N. Thornlow, Emily C. Cox
This is a single pdf file that contains: (1) supplementary methods; (2) supplementary table 1 (microarray glycans), supplementary table 2 (ADCs), and supplementary table 3 (primers); (3) supplementary figure 1 (ch735 Ab expression/purification), supp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01c71553219f5dcdc7cd6ef005716293
https://doi.org/10.1158/0008-5472.22423797.v1
https://doi.org/10.1158/0008-5472.22423797.v1
Autor:
Matthew P. DeLisa, Christopher A. Alabi, Matthew J. Paszek, Judith H. Merritt, Jordan L. Fuller, Michaela A. Jones, Dana N. Thornlow, Emily C. Cox
The specific targeting of differentially expressed glycans in malignant cells has emerged as an attractive anticancer strategy. One such target is the oncodevelopmental antigen polysialic acid (polySia), a polymer of α2,8-linked sialic acid residues
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::23fb561f809fbc514ef93bbb30769562
https://doi.org/10.1158/0008-5472.c.6511584.v1
https://doi.org/10.1158/0008-5472.c.6511584.v1
Autor:
Michelle R. Sorkin, Joshua A. Walker, Christopher A. Alabi, Dana N. Thornlow, Sneha R Kabaria, Francis Ledesma, John J Bohn
Publikováno v:
Bioconjugate Chemistry. 30:2452-2457
Site-specific modification of native antibodies has proven advantageous, as it enhances the properties of antibody-based bioconjugates without the need to manipulate the genetic code. However, native antibody modification is typically limited to stra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4af494a5b9912fe6d3a879f2af99b2e4
https://doi.org/10.1021/acs.bioconjchem.9b00522
https://doi.org/10.1021/acs.bioconjchem.9b00522
Autor:
Emily C. Cox, Joshua A. Walker, Christopher A. Alabi, Matthew P. DeLisa, Jacqueline B Plesset, Dana N. Thornlow, Michelle R. Sorkin
Publikováno v:
Bioconjugate Chemistry. 30:1702-1710
Antibody-drug conjugates utilize the antigen specificity of antibodies and the potency of chemotherapeutic and antibiotic drugs for targeted therapy. However, as cancers and bacteria evolve to resist the action of drugs, innovative controlled release
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85a2705595ac426da997127e688678a5
https://doi.org/10.1021/acs.bioconjchem.9b00244
https://doi.org/10.1021/acs.bioconjchem.9b00244
Autor:
Judith H. Merritt, Emily C. Cox, Jordan L. Fuller, Dana N. Thornlow, Matthew J. Paszek, Michaela A. Jones, Matthew P. DeLisa, Christopher A. Alabi
The specific targeting of differentially expressed glycans in malignant cells has emerged as an attractive anticancer strategy. One such target is the oncodevelopmental antigen polysialic acid (polySia), a polymer of α2,8-linked sialic acid residues
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82c8e83b58463b966cd33315cf0b6e5a
https://europepmc.org/articles/PMC6467748/
https://europepmc.org/articles/PMC6467748/
Publikováno v:
Biotechnology and Bioengineering. 112:2397-2405
Motile bacteria can overcome the transport limitations that hinder many cancer therapies. Active bacteria can penetrate through tissue to deliver treatment to resistant tumor regions. Bacterial therapy has had limited success, however, because this m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::da6854cb2bebfc2b2c2a465617ea8e34
https://doi.org/10.1002/bit.25645
https://doi.org/10.1002/bit.25645
Publikováno v:
ACS chemical biology. 12(3)
In response to the urgent need for new antibiotic development strategies, antimicrobial peptides (AMPs) and other synthetic polymers are being actively investigated as promising alternatives to traditional antibiotics. Although most AMPs display lyti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::573a741c5a47298be1cf2a28afcf7270
https://pubmed.ncbi.nlm.nih.gov/28068062
https://pubmed.ncbi.nlm.nih.gov/28068062
Publikováno v:
Nature chemistry. 8(6)
Synthetic macrocycles derived from sequence-defined oligomers are a unique structural class whose ring size, sequence and structure can be tuned via precise organization of the primary sequence. Similar to peptides and other peptidomimetics, these we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5114ffcc149c169a037705780f839de
https://pubmed.ncbi.nlm.nih.gov/27219704
https://pubmed.ncbi.nlm.nih.gov/27219704
Publikováno v:
Biotechnology and bioengineering. 112(11)
Motile bacteria can overcome the transport limitations that hinder many cancer therapies. Active bacteria can penetrate through tissue to deliver treatment to resistant tumor regions. Bacterial therapy has had limited success, however, because this m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b1cb4b22fde417cb94ca67768b85084f
https://pubmed.ncbi.nlm.nih.gov/25976712
https://pubmed.ncbi.nlm.nih.gov/25976712