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pro vyhledávání: '"Dana Michalkova-Papajova"'
Autor:
Claude Jacq, Zuzana Kozovska, Agnès Delahodde, Tibor Simonics, Dana Michalkova-Papajova, Julius Subik
Publikováno v:
Current Genetics. 38:248-255
Multidrug resistance in Saccharomyces cerevisiae mainly results from the overexpression of genes coding for the membrane efflux pumps, the major facilitators and the ABC binding cassette transporters, under the control of key transcription regulators
Publikováno v:
Antimicrobial Agents and Chemotherapy. 44:418-420
Yeast strains disrupted in the PDR1 , PDR3 , or PDR5 gene, but not in SNQ2 , exhibited higher sensitivity to mucidin (strobilurin A) than did the isogenic wild-type strains. Different gain-of-function mutations in the PDR1 and PDR3 genes rendered yea