Zobrazeno 1 - 10
of 56
pro vyhledávání: '"Dana Macejova"'
Autor:
Simona Kurekova, Zuzana Sevcikova Tomaskova, Natalia Andelova, Dana Macejova, Michaela Cervienkova, Julius Brtko, Miroslav Ferko, Marian Grman, Katarina Mackova
Publikováno v:
Cell Biology International. 46:947-964
Using H9C2 cardiomyoblasts, we have shown that all-trans retinoic acid (ATRA), the biologically active metabolite of vitamin A, affects mitochondrial dynamics and functions. The low dose (10 nM) ATRA stimulates the expression of nuclear retinoid rece
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2752c53113bb54a22481ed33aa99a8c6
https://doi.org/10.1002/cbin.11784
https://doi.org/10.1002/cbin.11784
Autor:
Alena Cernackova, Dana Macejova, Miroslav Tibensky, Lubica Horvathova, Boris Mravec, Andrej Tillinger
Publikováno v:
Anti-Cancer Drugs. 32:1011-1018
The sympathetic nervous system participates in the development and progression of several cancer types and this effect is mediated mainly via β-adrenergic signaling. However, the potential of β-adrenergic signaling blockade to prevent cancer develo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::225970986b27a1e7f5482643ea715d03
https://doi.org/10.1097/cad.0000000000001113
https://doi.org/10.1097/cad.0000000000001113
Autor:
Julius Brtko, Dana Macejova, Dana Strouhalova, Janette Bobalova, Lucia Toporova, Markéta Laštovičková
Publikováno v:
General physiology and biophysics. 38:135-144
Trialkyltins and triaryltins function as nuclear retinoid X receptors (RXR) agonists due to their affinity to the ligand-binding domain of RXR subtypes and function as transcriptional activators. We present the data on combined effects of all-trans r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::efe3d7fdab5218a0e21a606f52b89a1b
https://doi.org/10.4149/gpb_2018042
https://doi.org/10.4149/gpb_2018042
Publikováno v:
General physiology and biophysics. 39(4)
This work aimed to provide, in one isolation and separation step, an overview of the content of proteins with different solubility after treatment with all-trans retinoic acid, which is considered to be an important therapeutic agent, predominantly i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::581dc702ebd9da2e4c17dcafe9150f34
https://pubmed.ncbi.nlm.nih.gov/32902409
https://pubmed.ncbi.nlm.nih.gov/32902409
Autor:
Günter Vollmer, Shao-Nong Chen, Birgit M. Dietz, Florian Goerl, Dana Macejova, Guido F. Pauli, Judy L. Bolton, Oliver Zierau, Michael H. Muders, Annekathrin Martina Keiler, Richard B. van Breemen, Dejan Nikolic
Publikováno v:
The Journal of Steroid Biochemistry and Molecular Biology. 174:234-241
Supplements with estrogenic activities are intensively investigated as potential alternatives for the treatment of menopausal symptoms. These investigations include studies on their safety regarding potential breast cancer risks. Therefore, the aim o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::617dd1e5a4159eeec753e4c5f97b169f
https://doi.org/10.1016/j.jsbmb.2017.09.020
https://doi.org/10.1016/j.jsbmb.2017.09.020
Publikováno v:
General physiology and biophysics. 36:481-484
In the present study, we analyzed in vitro effects of natural and synthetic triorganotin ligands of nuclear retinoid X receptors in human MCF-7 breast cancer cells. Our data has shown that all-trans retinoic acid significantly reduced expression of R
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d5f55c8bcbc67cda51ded154a8bc23c
https://doi.org/10.4149/gpb_2017038
https://doi.org/10.4149/gpb_2017038
Autor:
Dana Macejova, Karol Kajo, Julius Brtko, Katarina Machalekova, Marianna Grigerova, Jan Podoba, Lucia Toporova
Potential causal associations of autoimmune thyroiditis (AIT) and papillary thyroid carcinoma (PTC) have been studied previously. The mRNA expression patterns of thyroid hormone receptors (TR), retinoid receptors (RAR), rexinoid receptors (RXR), dihy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3bebc2bd6fc5dff428cbaad1f8e1be9
https://europepmc.org/articles/PMC6757255/
https://europepmc.org/articles/PMC6757255/
Publikováno v:
Toxicology Letters. 254:32-36
Nuclear 9-cis retinoic acid receptors (retinoid X receptors, RXR) are promiscuous dimerization partners for a number of nuclear receptors. In the present study, we established a novel in vitro method for quantitative determination of the nuclear reti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8cdb5481f4ac81bda7f6f4da2f4171b6
https://doi.org/10.1016/j.toxlet.2016.05.005
https://doi.org/10.1016/j.toxlet.2016.05.005
Publikováno v:
Endocrine Regulations, Vol 50, Iss 3, Pp 154-164 (2016)
Retinoic acid (RA), an active form of vitamin A, regulates the embryonic development, male and female reproduction and induces important effects on the cell development, proliferation, and differentiation. These effects are mediated by the retinoid (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d8a20d9a44b80f1fef44f3271ce02dd
https://doaj.org/article/7e21c2371940453bbf0870e97980c88a
https://doaj.org/article/7e21c2371940453bbf0870e97980c88a
Autor:
Markéta Laštovičková, Julius Brtko, Dana Macejova, Lucia Toporova, Dana Flodrová, Janette Bobalova
Publikováno v:
General physiology and biophysics. 35:387-392
In the present study, we analyzed the cell lysates of human tumour cell lines representing two major clinically different types of breast cancer. Our main goal was to show the differences between them on proteomic level. Gel electrophoresis followed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c3a303c7f27f76fb6ae53d78d39201d
https://doi.org/10.4149/gpb_2016009
https://doi.org/10.4149/gpb_2016009