Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Dana M. Pirone"'
Publikováno v:
Journal of Microbiology & Biology Education, Vol 14, Iss 2, Pp 189-196 (2013)
This laboratory module simulates the process used by working scientists to ask and answer a question of biological interest. Instructors facilitate acquisition of knowledge using a comprehensive, inquiry-based approach in which students learn theory,
Externí odkaz:
https://doaj.org/article/96cd79083bed43f29288c3f30c089e9f
Publikováno v:
Biochemistry and Molecular Biology Education. 43:273-282
We describe a structured inquiry laboratory exercise that examines transcriptional regulation of the NOS2 gene under conditions that simulate the inflammatory response in macrophages. Using quantitative PCR and the comparative CT method, students are
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cc83da5dff6467ffe5cdb7b6d6f25c80
https://doi.org/10.1002/bmb.20870
https://doi.org/10.1002/bmb.20870
Autor:
Stella, Alimperti, Teodelinda, Mirabella, Varnica, Bajaj, William, Polacheck, Dana M, Pirone, Jeremy, Duffield, Jeroen, Eyckmans, Richard K, Assoian, Christopher S, Chen
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 114(33)
The integrity of the endothelial barrier between circulating blood and tissue is important for blood vessel function and, ultimately, for organ homeostasis. Here, we developed a vessel-on-a-chip with perfused endothelialized channels lined with human
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::073cb3af6c83b36ca9999e4327cf4f1e
https://pubmed.ncbi.nlm.nih.gov/28765370
https://pubmed.ncbi.nlm.nih.gov/28765370
Publikováno v:
Analytical Chemistry. 79:8557-8563
There is increasing demand for automated and quantitative cell culture technology, driven both by the intense activity in stem cell biology and by the emergence of systems biology. We built a fully automated cell culture screening system based on a m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23f8ca9dc368eac78983a03ce6705b39
https://doi.org/10.1021/ac071311w
https://doi.org/10.1021/ac071311w
Autor:
Christopher A. Lemmon, Lin Gao, Sami Alom Ruiz, Dana M. Pirone, Srivatsan Raghavan, Wendy Liu, Christopher S. Chen, Lewis H. Romer
Publikováno v:
The Journal of Cell Biology
Focal adhesion kinase (FAK) transduces cell adhesion to the extracellular matrix into proliferative signals. We show that FAK overexpression induced proliferation in endothelial cells, which are normally growth arrested by limited adhesion. Interesti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9558d94dc955fccae167bf9cf6426052
http://europepmc.org/articles/PMC2064187
http://europepmc.org/articles/PMC2064187
Publikováno v:
The Journal of Cell Biology
E-cadherin has been linked to the suppression of tumor growth and the inhibition of cell proliferation in culture. We observed that progressively decreasing the seeding density of normal rat kidney-52E (NRK-52E) or MCF-10A epithelial cells from confl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b731b0ef7aeb3c0e9a4578339f4aa771
http://europepmc.org/articles/PMC2063843
http://europepmc.org/articles/PMC2063843
Publikováno v:
Current Genomics. 5:567-574
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::813b08bd8dc1873289ef684deab189ad
https://doi.org/10.2174/1389202043348779
https://doi.org/10.2174/1389202043348779
Publikováno v:
Molecular Biology of the Cell. 15:2943-2953
Changes in vascular endothelial (VE)-cadherin–mediated cell-cell adhesion and integrin-mediated cell-matrix adhesion coordinate to affect the physical and mechanical rearrangements of the endothelium, although the mechanisms for such cross talk rem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5865e00c1911d2520e8de5f6e17ee015
https://doi.org/10.1091/mbc.e03-10-0745
https://doi.org/10.1091/mbc.e03-10-0745
Publikováno v:
Developmental Cell. 6(4):483-495
Commitment of stem cells to different lineages is regulated by many cues in the local tissue microenvironment. Here we demonstrate that cell shape regulates commitment of human mesenchymal stem cells (hMSCs) to adipocyte or osteoblast fate. hMSCs all
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8977ff510486b19b986ade8fbd06878b
Publikováno v:
Proceedings of the National Academy of Sciences. 100:1484-1489
We describe an approach to manipulate and measure mechanical interactions between cells and their underlying substrates by using microfabricated arrays of elastomeric, microneedle-like posts. By controlling the geometry of the posts, we varied the co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e878d13e3d06289f0207cf3377918ef
https://doi.org/10.1073/pnas.0235407100
https://doi.org/10.1073/pnas.0235407100