Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Dana M. Cairns"'
Publikováno v:
ACS Omega, Vol 3, Iss 10, Pp 12392-12402 (2018)
Externí odkaz:
https://doaj.org/article/757fa8dd684e44c1b20ebf8e73b2f3d0
Autor:
Dana M. Cairns, Karolina Chwalek, Yvonne E. Moore, Matt R. Kelley, Rosalyn D. Abbott, Stephen Moss, David L. Kaplan
Publikováno v:
Stem Cell Reports, Vol 7, Iss 3, Pp 557-570 (2016)
Limited availability of human neurons poses a significant barrier to progress in biological and preclinical studies of the human nervous system. Current stem cell-based approaches of neuron generation are still hindered by prolonged culture requireme
Externí odkaz:
https://doaj.org/article/12589b55d39347adbf90d6a43e39c764
Publikováno v:
Biology Open, Vol 7, Iss 1 (2018)
Zika virus (ZIKV) is a mosquito-transmitted flavivirus with a causative link to microcephaly, a condition resulting in reduced cranial size and brain abnormalities. Despite recent progress, there is a current lack of in vivo models that permit the st
Externí odkaz:
https://doaj.org/article/f0ce989112554e62a8b42328342d5364
Publikováno v:
Alzheimer's & Dementia. 18
Publikováno v:
Journal of Alzheimer's disease : JAD. 88(3)
Background: Varicella zoster virus (VZV) has been implicated in Alzheimer’s disease (AD), and vaccination against shingles, caused by VZV, has been found to decrease the risk of AD/dementia. VZV might reside latently in brain, and on reactivation m
Autor:
Isabella A. Silveira, Adam S. Mullis, Dana M. Cairns, Anna Shevzov-Zebrun, Jordyn Whalen, Alexa Galuppo, Katherine G. Walsh, David L. Kaplan
Publikováno v:
Free radical biologymedicine. 186
Alzheimer's Disease (AD) is a neurodegenerative disorder that can cause life-altering and debilitating cognitive decline. AD's etiology is poorly understood, and no disease-modifying therapeutics exist. Here, we describe the use of 2D and 3D tissue c
Publikováno v:
Proc Natl Acad Sci U S A
Bioelectronic scaffolds that support devices while promoting tissue integration could enable tissue hybrids with augmented electronic capabilities. Here, we demonstrate a photo–cross-linkable silk fibroin (PSF) derivative and investigate its struct
Autor:
Dana M. Cairns, Dorothy Dulko, Jeffrey K. Griffiths, Yoav Golan, Theodora Cohen, Ludovic Trinquart, Lori Lyn Price, Kirthana R. Beaulac, Harry P. Selker
Publikováno v:
JAMA network open. 5(2)
Oral anthelmintic niclosamide has potent in vitro antiviral activity against SARS-CoV-2. Repurposed niclosamide could be a safe and efficacious COVID-19 therapy.To investigate whether niclosamide decreased SARS-CoV-2 shedding and duration of symptoms
Autor:
Zaira Martín-Moldes, Dana M. Cairns, Vincent Fitzpatrick, Chunmei Li, Anna Deck, Anne Valat, David L. Kaplan, Ruben Torres-Sanchez
Publikováno v:
Biomaterials
Our goal was to generate functionalized 3D-printed scaffolds for bone regeneration using silk-hydroxyapatite bone cements and osteoinductive, proangiogenic and neurotrophic growth factors or morphogens for accelerated bone formation. 3D printing was
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2be658b8c65f1cc5f8324ea188a3782
https://europepmc.org/articles/PMC8408341/
https://europepmc.org/articles/PMC8408341/
Autor:
Dana M. Cairns, Constantine G. Razis, Mattia Bonzanni, Marisa D. Williams, Jonathan M. Grasman, Annie Golding, Michael Levin, David L. Kaplan
Publikováno v:
ACS Biomater Sci Eng
Scar formation is a natural result of almost all wound healing in adult mammals. Unfortunately, scarring disrupts normal tissue function and can cause significant physical and psychological distress. In addition to improving surgical techniques to li